Many of us know the properties of the drug "Levomycetin", with which you can cope with various ailments. It is effective in infectious diseases of the gastrointestinal tract, including those accompanied by diarrhea, is widely used in ophthalmic practice in diseases of bacterial etiology. However, not always the use of this medication is justified, therefore the doctor can prescribe an analog of "Levomycetin". But what exactly means can be recommended, let's try to understand.
Pharmacological properties of the drug "Levomycetin"
This antibiotic, which has a wide spectrum of action, thanks to its fat-soluble properties, easily penetrates the cell membrane of pathogenic microorganisms and reacts with the substance of bacterial ribosomes. The result of such an impact is a disruption of the formation of peptide bonds and protein synthesis. Thus, it turns out that the active substance of the drug has a bactericidal and bacteriostatic effect.
"Levomycetin" is active against many strains of microorganisms that are resistant to tetracyclines, sulfonamides and penicillins. But on the pathogenic protozoa - Mycobacterium tuberculosis and mushrooms - the medication, unfortunately, does not work.
Resistance to this agent in microorganisms develops very slowly. Due to this feature, as well as high toxicity, the drug is used to treat severe infectious diseases, in which less toxic antibacterial medicines are ineffective.
Indications for use and forms of release
Since the drug is used in several fields of medicine, pharmacists have taken care of the convenience of use and developed three basic forms of the drug. The first is alcohol solution, which is intended for external use. It is prescribed for the treatment of trophic ulcers, which do not heal for a long time, and also burns of II and III degrees. It is often recommended a remedy for purulent skin lesions, furuncles and fissures of nipples in nursing mothers.
Medication in the tablet form is advised for patients suffering from such diseases as dysentery, paratyphoid, typhoid fever, brucellosis, salmonellosis, tularemia, brain abscess, pneumonia. No less effective is the drug for various forms of fever CU, inguinal lymphagranulem, iersiniosis, psittacosis, bile duct infection, purulent peritonitis, chlamydia, purulent wound infections, erlichiosis, purulent otitis and ailments of the urinary tract of bacterial origin.
The third form of the remedy is eye drops. They are used in ophthalmic practice to treat and prevent diseases such as keratitis, conjunctivitis, blepharitis.
Side effects of the agent
This drug, like other drugs, in addition to positive pharmacological properties, has a number of side effects that may appear during therapy.
The use of the drug in tablet form can cause dysbacteriosis, dyspepsia, vomiting, nausea, diarrhea, and irritation of the mucous membrane of the throat and mouth. The hemopoietic system can also respond to the reception of the remedy, which manifests itself in the form of thrombocytopenia, granulocytopenia, erythrocytopenia, reticulocytopenia and leukopenia. Less often the patient may develop aplastic anemia or granulocytopenia. From the side of the nervous system, the response to Levomycetin tablets can be peripheral neuritis, confusion, visual and auditory hallucinations, psychomotor disorders, and others.
Adverse reactions to the use of drugs in the form of a solution can be an allergy, manifested as a skin rash or angioedema.
Structural analogue of the agent
The main active ingredient of the drug is chloramphenicol. Therefore, the main structural analogue of "Levomycetin" is a drug with the same name "Chloramphenicol". Indications for its use are completely identical to those described in the instructions for the application of "Levomycetin".
This remedy is produced in three basic forms. The first - tablets and capsules, containing 0.5 and 0.25 g of the active ingredient. The second form is 25% eye drops, the third - powder, intended for the preparation of solution for injection.
It should be noted that, like Levomycetin, analogues containing chloramphenicol are broad-spectrum antibiotics and should be prescribed directly by a physician. In cases of self-administration of drugs in this group, the risk of side effects increases.
The drug "Levovinisol"
Another structural analogue of "Levomycetin", which can now be purchased at a pharmacy, is known under the trade name "Levovinizol". This drug is based on chloramphenicol and a number of excipients. The medicine is produced in the form of aerosol, liniment, powder for the preparation of solution and ready-mixed alcohol solution.
Assign this drug for various bacterial skin infections caused by sensitive microorganisms. In addition, doctors often use medicines to treat patients with infected deep and superficial burns, bedsores, trophic ulcers, non-healing wounds, boils, and also recommend medicines to nursing women with nipple cracks.
In contrast to the drug "Levomycetin", modern analogues for topical application, in particular medicament "Levovinisol", have a small list of side effects, so they can be used even to treat babies from birth.
As for contraindications, there are not too many of them. The drug is prohibited for people with hypersensitivity to components, oppression of bone marrow hematopoiesis, as well as for those who suffer from acute intermittent porphyria, deficiency of glucose-6-phosphate dehydrogenase, renal or hepatic insufficiency, psoriasis, fungal epidermal lesions, eczema.
Trying to understand the question of what synonyms and analogues have a drug "Levomycetin", it is necessary to mention the medicine "Synthomycin". This remedy is often prescribed for patients with infected 2-3 degree burns, non-healing trophic ulcers and various wound infections.
The drug is based on chloramphenicol. As auxiliary components for the creation of a single dosage form, the pharmacists used the oil of ordinary castor seeds, sorbic acid, purified water, emulsifier No. 1 and carmellose sodium 70/450 "O".
The drug "Metronidazole"
Antiprotozoal and antibacterial agents are used in various areas of medicine. It is prescribed for protozoal infections, joint and bone diseases, and for ailments of the abdominal cavity of bacterial etiology. This drug is produced in four basic medicinal forms: in the form of vaginal gel, infusion solution, suppositories and tablets.
This analogue of "Levomycetin" from diarrhea should be used only as prescribed by the doctor, which will determine the duration of the therapeutic course and dosage. Otherwise, the risk of developing adverse reactions of the body increases at times. In this case, the central nervous system suffers, and patients complain of convulsions, headache, weakness, insomnia, dizziness, irritability, drowsiness, ataxia, confusion and even hallucinations. In addition, self-administration of the drug can aggravate the patient's condition by increasing diarrhea. Also, vomiting, dry mouth, complete loss of appetite and other digestive system disorders may occur. Therefore, like the "Levomycetin", instructions for the use of analogues recommend taking only the doctor's prescription. This will help avoid unwanted side reactions and quickly cope with an already existing problem.
Another analogue of "Levomycetin" is the tablet "Ciprofloxacin". This drug has antibacterial action and is active against pathogens of many ailments of the genitourinary system and the gastrointestinal tract. The dosage of the drug and the duration of the therapeutic course are calculated individually.
This drug is not a structural analogue of the drug "Levomycetin", but the pharmacological properties of these two drugs are very similar. In addition, they can be used for diarrhea caused by various pathogenic microorganisms. As for contraindications to taking the antibiotic "Ciprofloxacin", there are a lot of them. First, it is strictly forbidden to use the medicine for the treatment of children and adolescents under the age of fifteen. Secondly, it is not recommended to apply the drug to women during pregnancy and lactation. This is explained by the fact that this analogue of "Levomycetin" is a representative of the antibiotics of the quinolone series, which can accumulate in bone and cartilage tissues, destroying their structure. And this is very dangerous both for the developing crumbs in the womb, and for the baby, whose mother is breastfeeding.
Another antibacterial drug that has proven itself in the treatment of intestinal infections that cause diarrhea is the drug Amoxicillin. Like the drug "Levomycetin", its analogs should be used only on the recommendation of a doctor. After all, all antibiotics have a large number of side effects. Therefore, appointing an antibacterial agent to the patient, the specialist not only calculates the dosage of the drug, but also acquaints with the rules of admission. He will also include probiotics in the complex therapy, which will help mitigate the negative effect of the antibacterial agent and maintain the intestinal microflora in a normal state.
Analogues of "Levomycetin" for children
If diarrhea has started in a child, self-medication is not the best way to solve the problem. And there is no need to talk about the independent use of antibacterial drugs. The first thing to do is to consult a specialist for help. The doctor will examine the crumbs, carry out a series of studies and designate a therapy that is safe for the small patient. Of course, if it is determined that the cause of diarrhea is precisely a bacterial infection, then treatment without antibiotics is unlikely to be possible. But this does not mean that the doctor will prescribe the drug "Levomycetin". Analogues for children are selected according to the age group of the patient, the severity of the disease, and also according to the individual characteristics of the crumbs (allergy, intolerance of certain medications and their constituents, chronic diseases, etc.).
Most often in such cases, the synthetic drug "Nifuroxazide", which belongs to the group of nitrofurans, is used. It is produced both in tablet form and in suspension, this analogue of "Levomycetin". Tablets are usually prescribed for adults and children of senior school age, but in liquid form, the drug can be given to crumbs.
What is the substitute for medicine in ophthalmology?
Considering the properties of the drug "Levomycetin" and its analogs, do not forget that this antibacterial drug is available in various forms and can be used in several areas of medicine. Thus, eye drops are widely used in ophthalmic practice for the treatment of diseases caused by bacterial infections. The agent can be prescribed to patients suffering from conjunctivitis, blepharitis, keratitis, uveitis and other ailments.
However, despite the high effectiveness, the medicine can not be recommended to everyone, since the list of contraindications to its reception is large enough. According to the information contained in the instructions for use, the drug is strictly prohibited for children and adolescents under the age of 18, pregnant and lactating women. Patients with diseases of the hematopoiesis system, renal or hepatic and insufficiency and other systemic ailments can also not use the drug "Levomycetin" (eye drops). Analogues containing more secure components in such situations are the only correct variant of the solution of the problem. Depending on the age of the patient and the complexity of the disease, the doctor can recommend such drops as "Albucid", "Okomistin", "Normaks", "Floxal" and others.
The drug "Albucid"
Like the drug "Levomycetin" (drops), the analogue "Albucid" is a medicine with a bacteriostatic effect. This drug is prescribed to patients - regardless of age - for the prevention and treatment of inflammatory infectious eye diseases, such as keratitis, conjunctivitis, blepharitis, etc. The only thing that should be paid attention to is that 20% solution of the drug is used to treat children , But the representatives of the older age group showed 30%.
If you consider possible side effects of the medication, then, as a rule, they are very rare and do not require symptomatic treatment.
What you need to know about the drug "Levomycetin" and its analogues?
Medicines, similar in structure with the drug "Levomycetin", not so much. But here medicines with identical pharmacological properties are more than enough, and which of them to choose - should be determined exclusively by the doctor. Only an expert who has diagnosed and determined the degree of severity of the disease and its etiology can recommend the patient taking Levomycetin.
Analogues (with diarrhea, for example) in the form of tablets and suspensions should also be taken on the advice of a doctor, clearly following the dosing system. This will reduce the risk of side effects.