"Vesticap": instructions for use. Analogs of the drug and reviews about it

The drug "Vesticap" includes beta-histidine dihydrochloride as an active ingredient. Additional components: lactose monohydrate, potato starch, sodium carboxymethyl starch, magnesium stearate, colloidal silicon dioxide. Tablets "Vesticap" are not available. The medicine is made in the form of capsules of 8 and 16 milligrams, they differ in the color of the body. Inside the capsules there is a powder of white or slightly creamy hue. In pharmacies, the medicine can be purchased for 140 rubles (and higher, depending on the point of sale). This is a low price for Vestikap.

Instructions. Mechanism of action of the drug

The remedy is classified as a histamine drug. The active substance affects H3 and H1 receptors in the vestibular nuclei of the central nervous system and in the inner ear. Due to direct agonistic action, the permeability and microcirculation in the capillaries is improved, the endolymph pressure is stabilized in the cochlea and labyrinth. There is an increase in blood flow in the basilar artery. The drug accelerates recovery of the function after vestibular unilateral neurrectomy. This effect is manifested by antagonism with H3-histamine receptors. As a result, vestibular central compensation is facilitated and accelerated. The drug "Vesticap" (the instruction for use contains such information) exerts a pronounced central influence, generates potentials in the neurons of the medial and lateral vestibular nuclei in a dose-dependent manner. A stable therapeutic effect is observed after two weeks.

Pharmacokinetic properties

The product undergoes rapid absorption. There is a low connection with plasma proteins. Within three hours, the concentration of the drug in the blood reaches a maximum. In the process of decomposition, 2-pyridylacetic acid and demethylbetahistine are formed. Almost completely (80-90%) excreted with the kidneys throughout the day. A small part of the decay products is excreted through the intestine.

Appointment

The medicine "Vesticap" is recommended for use in Meniere's syndrome, accompanied by noise in the ears, hearing loss and dizziness. The medication effectively eliminates such complications as nausea and vomiting. The medication is prescribed for symptomatic therapy of vertigo (dizziness of the vestibular nature).

Contraindications

Not recommended for glucose intolerance, hypersensitivity to the components of the drug, during lactation. Contraindicated treatment of pregnant, lactating. The medication "Vesticap" is not prescribed (the instruction for use warns about it) in childhood. Nursing patients should stop feeding for the entire period of therapy. Caution during admission should be observed in the presence of ulcerative lesions of the digestive system (in history including), bronchial asthma, pheochromcytoma. Patients with these pathologies should undergo treatment under close medical supervision. In some cases, an adjustment of the reception scheme may be required.

Dosing regimen

"Vesticap" medication instructions for use recommend drinking while eating. For capsules at 8 milligrams, a single dose is 1-2 pcs., In 16 mg - 1 pound. The drug is taken three times a day. As a rule, the improvement occurs already at the initial stages of therapy. However, a stable effect is observed after fourteen days. For several months, the activity of the drug may increase. Therapy is long. The duration of the course is determined by a specialist individually.

Side effects

The medicine provokes abdominal pain, vomiting, angioedema (rarely). To undesirable consequences include dyspepsia, bloating, rash. In case of occurrence of the specified negative reactions it is necessary to consult with the expert. In case of an overdose, the drug in question provokes an exacerbation of these symptoms. Intoxication is accompanied by drowsiness (in case of taking up to 640 mg of the drug), cardiovascular complications (when taking more than 640 mg or when combined with other medicines). In such situations, symptomatic treatment is prescribed, and it is necessary to visit a doctor. With timely access to a specialist, the risk of complications is significantly reduced, and the manifestations of intoxication are eliminated in a short time. As a first aid measure recommended gastric lavage.

Than to replace a medicine? The most popular analogs

"Vesticap" - as a preparation of the histamine series - has a lot of drugs-synonyms (or generics) that have a similar therapeutic effect. The best option would be the treatment with the original Betaserk. However, in comparison with others, this medicine is quite expensive (about 400-600 rubles). To the most popular and inexpensive drugs in Russia, which can replace the drug "Vesticap", you should include drugs "Tagist" and "VestiBo." All of them contain one active substance, however, in different concentrations. Depending on its content, the price is also set.

The drug "VestiBo"

Available in tablet form. The drug has a slight agonistic effect on the H1-receptors. The drug exhibits vasodilating and histamine-like activity. There is a fairly strong effect on H3 receptors. The drug does not provoke drowsiness and does not have a sedative effect, like some other analogues of "Vesticap". Vestibo is not recommended in the first trimester, with caution (for life indications) is prescribed in the second and third trimesters of pregnancy.

The medicine "Tagist"

The medication can be prescribed both as a treatment and for the prevention of vestibular vertigo of various etiologies. The drug is also available in the form of tablets. Contraindications include age under 18 years, pregnancy. Do not prescribe medication to nursing patients. When taking the remedy, there may be a breakdown in the activity of the digestive tract, reaction of hypersensitivity, angioedema.

What about the drug "Vesticap" reviews?

In general, with regard to the tolerability of the drug, the patient's words indicate that the remedy rarely provokes side effects. The resulting undesirable consequences are usually eliminated after the drug is withdrawn and do not require additional intervention. However, experts say that The drug does not affect the speed of psychomotor reactions and the ability to concentrate attention. In this regard, the drug is allowed to admit to persons whose activities are considered potentially dangerous. Doctors speak positively about the effectiveness of the drug. However, in some cases, the therapeutic effect is increasing for several months.

additional information

Medication "Vesticap" is suitable for use for three years. Keep the medicine in a dark place, away from children. The temperature should not be more than 25 degrees. Experts note that the drug "Vesticap", like the similar medicines of this group, is considered a fairly strong drug, despite the fact that in some cases, the effect develops gradually. The product is manufactured by the Russian pharmaceutical company Ozon. The cost of the medication varies from 150 to 200 rubles (or more). The remedy is given by prescription.