"Ubistizin Fort". Local anesthetics

What is the drug "Ubistizin Fort" for? Instruction, as well as indications for the use of this medication will be presented later.

From the materials of this article, you will learn about the form in which the product is manufactured, how much it costs, whether it can be prescribed to pregnant women and what properties it possesses.

Composition, packaging and shape

The drug "Ubistezin forte", the price of which is indicated below, is available in the form of a solution for injections. Its active ingredients are articaine hydrochloride and epinephrine hydrochloride. Also, the composition of the medicament includes auxiliary components in the form of water for injection, sodium chloride and sodium sulfite.

The injection solution goes on sale in the carpules, which are placed in a metal container.

Pharmacodynamics of the drug

What is a drug such as Ubestizin Fort? According to the instructions, this is a combined remedy for local anesthesia. It is used for small surgical interventions, in particular in dental practice.

The action of this drug determines the constituent substances in its composition.

Local anesthetics containing articaine belong to the tiafen group anesthetics.

In comparison with lidocaine or novocaine, such a preparation is characterized by a momentary action. The anesthetic effect is observed after a lapse of 0.5-3 minutes. As for the above funds, they begin their action only after 4-5 and 5-10 minutes, respectively.

The duration of the anesthetic effect after the administration of the drug Ubistezin Fort is 45 minutes.

It should be specially noted that this medication is twice as strong as lidocaine. Moreover, it is very quickly excreted from the body, does not inhibit the healing of wounds and is less toxic. Such a solution for injections is shown to the elderly, as well as to children from 5 years of age.

As for epinephrine, it is a vasoconstrictor. It contributes to the narrowing of the vessels, thereby strengthening and prolonging the action of the anesthetic. This exposure to the drug causes tissue hypoxia, resulting in suppressed excitability of the nerve endings, which significantly reduces pain.

The drug "Ubistezin forte" is an anesthetic with a low content of vasoconstrictor. A small amount of epinephrine does not contribute to high blood pressure, does not cause tachycardia, and has no significant effect on the cardiovascular system.

Pharmacokinetics of injection solution

Local anesthetics have a high penetrating power. And the drug we are considering is no exception. It binds to plasma proteins by 95% and is practically not excreted with the woman's milk and does not penetrate the placental barrier.

The half-life of this drug is 22-26 minutes.

Indications for use

The drug "Ubistezin forte" is actively used for minor dental operations:

• With uncomplicated removal of the tooth;
• At filling of carious teeth;
• When preparing for prosthetics or so-called teeth grinding.

It should also be noted that this medication is used for intercostal, retrobulbar and paravertebral anesthesia, blockade of the stellate node, trigeminal nerve, external genital organs and brachial plexus.

Contraindications for use

Injection solution "Ubistezin forte" is not recommended for:

• Bronchial asthma and hypersensitivity to sulfites;
• Angle-closure glaucoma;
• Hypersensitivity to drug substances;
• Paroxysmal tachycardia;
• Severe hepatic insufficiency;
• Cardiogenic shock;
• Concomitant therapy with tricyclic antidepressants and non-selective beta-blockers;
• Hyperthyroidism.

Careful use of the solution

With special care this medication is prescribed for:

• Diabetes mellitus;
• Chronic heart failure;
• Arterial hypertension;
• Atrioventricular blockade;
• Renal failure;
• Inflammation in the field of anesthesia;
• In old age;
• Weakened state of the patient.

How to apply Ubestezin Fort solution?

This medication can be used for healthy people with minor dental interventions. At a time, about 1-2 carpules are used, which corresponds to 2-4 ml. The maximum allowable dose of this solution within 2 hours is 2.5-3 carpules.

With uncomplicated removal of the tooth drug is injected under the mucosa in an amount of 1.7 ml (per tooth).

When cutting the sky, apply 0.1 ml of the solution, while crotching the crotch - about 5-15 ml, and with tonsillectomy - 5-10 ml (one tonsil).

If the medication is used for conductive anesthesia (for example, intercostal, retrobulbar, epidural, paravertebral or sacral), as well as with blockades (trigeminal nerve, paracervical, brachial plexus or stellate unit), doctors use from 1 to 30 ml of solution (depends on volume Anesthesia and injection site).

Adverse events

According to the instructions, the drug in question can cause the following side reactions:

• Nausea, "clouding" in the eyes, vomiting, nerve damage;
• Headache, redness of the skin, muscle tremor, tachycardia;
• Impaired consciousness (possible loss of it) and breathing, drop in blood pressure, muscle twitching;
• Generalized seizures, itching, conjunctivitis, oppression of cardiovascular activity;
• Edema at the injection site, swelling of the lips, rhinitis.

Overdose Symptoms

An overdose of this drug causes the following undesirable symptoms: tachycardia, dizziness, impaired consciousness, bradycardia, anxiety, lowering blood pressure.

When observing such deviations, it is required to stop all manipulations, to lay the patient and restore the patency of the airways. Regular monitoring of heart rate and blood pressure should also be performed.

The affected person is shown to have artificial ventilation. With cramps, the patient is intravenously injected with barbiturates, in case of a vascular collapse - "Adrenaline", in shock - electrolytes and glucocorticosteroids, with tachycardia - selective beta-adrenoblockers, and with increasing blood pressure - peripheral vasodilators.

Fertilization period, feeding

Can I use Ubistezin Fort during pregnancy? Experts say that this drug does not pass through the placental barrier. In this regard, it is absolutely safe anesthetic, which has no effect on the fetus.

As for nursing mothers, they should not interrupt breastfeeding, since the active ingredients of the medication are not excreted together with milk.

Reviews and Price

The cost of this tool varies from 2000-2100 rubles (for 50 karpul).

Dentists speak about the preparation in question only on the positive side. The effectiveness of this medication is explained by many factors.

A high percentage of binding of the active substance to proteins indicates that about 95% of the drug enters the bloodstream as an inactive substance. Due to this, it can be safely concluded that the systemic toxicity of this drug is very low. The effectiveness of anesthesia is quite high.

It should also be noted that "Ubistezin forte" is very quickly excreted from the body. If a second injection is required, the toxic effect of this medication will be markedly lower than that of other anesthetics.