Antipyretic drugs: the principle of action, especially during pregnancy and lactation

Antipyretic drugs in pharmacology are called medicines, which can reduce body temperature in various diseases. Antipyretics belong to the group of NSAIDs, that is, nonhormonal (nonsteroidal) medicines, which, in addition to antipyretic drugs, have an anesthetic and anti-inflammatory effect. These drugs include drugs that are based on paracetamol, aspirin and ibuprofen.

The rise in body temperature of the person is caused by special biologically active substances - pyrogens, which are formed when exposed to the body of toxins, pathogens of infections and other irritants. Pyrogens, in turn, irritate certain areas of the hypothalamus, which leads to an increase in body temperature due to the limitation of heat transfer processes. This manifests itself in the narrowing of the superficial blood vessels, and consequently in the reduction of the blood supply to the skin and the release of heat from its surface. Antipyretics act on the receptors of the hypothalamus, reducing their sensitivity to pyrogens, resulting in decreased heat production by the body and improves heat transfer by expanding the blood vessels. Thus, the normal body temperature is restored.

It should be borne in mind that antipyretics should not be used to prevent fever, since they do not affect the maintenance of normal body temperature . For these biological processes, absolutely other mechanisms correspond in which pyrogens do not participate.

At pregnancy and during a lactemia it is necessary to concern with special care to reception of any antipyretic preparations. To date, antipyretics for pregnant women have been allowed only on the basis of paracetamol (for example, such as panadol). Also they can be used for headaches. Contraindications for drugs based on aspirin. But often the doctor prescribes pregnant "folk" antipyretic drugs, plentiful drink and herbal teas in conjunction with grindings. But in any case, self-medication does not follow, so as not to harm the child and yourself.

Antipyretic drugs for lactating women should be strictly dosed, and their intake is limited to one-time use, because to date their influence on lactation and the child's condition has not been fully understood. It is considered compatible with breastfeeding paracetamol, ibuprofen, naproxen, ketoprofen. Serious contraindications have analgin, which has a negative impact on the kidneys and hematopoietic system. In addition, it is able to cause allergic reactions in children breast-feeding.

It is most reasonable to take advantage of available folk remedies, which act no worse than pharmacies, when the body temperature rises. The most famous and effective is honey. A tablespoon of honey should be dissolved in a glass of warm water and a drink. In addition to antipyretic effect, honey has an excellent tonicity and contains many useful substances and microelements, which are so necessary for a weakened organism.

A similar action has freshly squeezed orange juice and cranberry berries, from which you can prepare an infusion, or you can eat fresh. An excellent antipyretic effect is possessed by cherry and cherry juice, pears and pear compote. At the same time cherry juice should not be bought in the store, and compote can be drunk in unlimited quantities. These remedies are not only very tasty, but also useful.

You can prepare vitamin infusions from the leaves of the nettle or dandelion, which also contribute to lowering the body heat and activating the body's defenses, since they contain a large number of vitamins. Take infusions need two tablespoons four times a day.