The drug "Normix Alpha": reviews, instructions for use and composition

It is not a secret for anyone that antibiotics are used to treat various diseases. Some microorganisms are more sensitive to them, and some are less. And before using this or that antibiotic, you should always consult a doctor. After all, only an experienced specialist knows which treatment scheme suits you most.

Today we will tell you about what is prescribed such a drug as "Alpha Normix". Instructions for use, price, reviews of consumers and doctors, as well as side effects of the drug will be presented below.

Description, composition, packaging and shape

In what form is the antibiotic Alpha Normix made? Consumer testimonials say that you can buy this medication in a pharmacy in two different forms.

• Round bulging pills of pink color, covered with a shell. Their active substance acts rifaximin. Also included in the drug are additional elements that are presented in the form of sodium carboxymethyl starch, palmitostearate glycerin, microcrystalline cellulose, colloidal silicon dioxide, hypromellose, talc, E172, disodium edetate, titanium dioxide and propylene glycol. In the sale of tablets come in blisters of 12 pieces. In one cardboard box there can be 1 or 3 blisters.
• Orange granules intended for the preparation of a suspension. The finished solution has a cherry flavor and characteristic aroma. The active ingredient of this form is rifaximin. Also, the suspension contains such auxiliary components as carmellose sodium, sodium benzoate, kaolin, microcrystalline cellulose, "wild cherry" flavor, pectin, sucrose and sodium saccharinate. You can buy the drug in dark glass bottles of 5 ml each. Also included is a dosage cup.

Pharmacodynamic characteristics

What is remarkable about the medication "Alpha Normix"? Instructions for use (reviews about this tool are very ambiguous) reports that this drug contains the active ingredient in the alpha form. It refers to antibiotic drugs that belong to the rifampicin group.

The active component of this agent binds the beta subunits of the DNA-dependent enzyme of harmful microorganisms, and rifaximin inhibits the synthesis of RNA, as well as proteins in bacterial cells. This process is irreversible. As a result, microbes are killed.

This drug is sensitive to a variety of gram-negative bacteria and Gram-positive microorganisms.

Properties of the medicine

What properties are inherent in the medicine "Alpha Normix"? Reviews of doctors, as well as medical experience shows that this drug is able to reduce:

• The number of microbes that are present in the diverticula of the colon. As a result of this influence, inflammation around the diverticulum sac decreases, symptoms are eliminated and the risk of complications in diverticular disease is reduced.
• Ammonia, as well as other products of the life of bacteria.
• Antigenic specific stimulus that initiates and maintains chronic inflammation in the intestine.
• The risk of infectious complications that can occur both after and during colorectal surgeries.
• The proliferation of microbes, but only if it is increased because of the syndrome of excessive growth of harmful microorganisms in the intestine.

Kinetic Properties

Is Normix Alpha absorbed? The doctors' comments can not give an answer to the question posed. For it you should refer to the attached instructions. According to her, in the intestine the antibiotic is practically not absorbed (less than 1%), and, consequently, does not enter the systemic bloodstream. Therefore, the medicament under consideration acts only on the microflora of the said organ, significantly reducing the level of its pathogenicity. In this case, the drug rarely causes serious side effects.

After taking the drug in the blood, it is not detected (sometimes it can be present in small amounts). At the highest daily dosage equal to 0.8 g, the peak of its concentration in the intestine is reached within 3 hours. Also, the drug is found in the urine (less than 1%).

Indications for use

At what conditions is prescribed such a drug as "Alpha Normix"? Children (reviews of antibiotics are presented at the end of the article) and adult patients are recommended for the treatment of infectious diseases that are sensitive to its effects.

According to the instructions, this medication is very effective when:

• Diarrhea of the "traveler";
• Syndrome of excessive growth of microbes in the intestine;
• Hepatic encephalopathy ;
• Diverticular disease of the colon;
• Acute infections in the digestive tract;
• Inflammation of the intestine (chronic);
• Prevention of complications after surgical interventions in the colorectal area.

Contraindications to taking oral medication

When should you not prescribe the antibiotic Alpha Normix? Instruction, reviews of experienced specialists indicate that there are not very many contraindications for this medicine. These include:

• Ulcer, erosion in the intestine;
• Intestinal obstruction;
• The presence of allergic reactions to the components of the drug.

It should also be noted that the finished drug suspension is not recommended for use in cases of intolerance to the antibiotic or its individual ingredients.

How to take "Alpha Normix" (tablets)?

Experts say that the drug in the form of tablets is no less effective in granules. It should be taken orally, without chewing and not dividing in half.

The dosage of this product, as well as the duration of its administration, are determined individually by the attending physician.

Patients who have reached the age of 12 years, this drug should be taken one tablet every 8 hours or two tablets every 12 hours.

Therapy should be continued no longer than one week. If necessary, the course can be repeated, but not earlier than in a month.

How to prepare a solution of "Normix Alfa"?

The doctors' comments say that the medicine in the form of granules is most often prescribed to children.

To prepare the drug suspension, add water (up to the first mark) to the bottle with the drug. Next, the container is shaken well. After that, the liquid is refilled in the vial (until the next mark).

The dosage recommended by the doctor is measured with a measuring cup, which, together with the medicine, is contained in a cardboard box.

How long can I store the prepared solution of Normix Alpha? Experts say that the suspension should be used within one week, but this is only if all the conditions for its storage have been met. Before using the drug, it must be shaken thoroughly.

Application in childhood

At what age do they prescribe the Normix Alpha suspension? Pediatricians say that this drug can be given to a child from 2 years.

The daily dosage of the drug for children 2-6 years is 200-600 mg, which corresponds to 5-10 ml of the suspension. The indicated amount of the agent is divided into three steps.

Babies at the age of 6-12 years are recommended to take a medication in a dose of 400-800 mg (or 10-20 ml of suspension) twice a day.

As for teenagers over 12 years of age, they are prescribed 600-1200 mg of antibiotic (or 10-20 ml three times) per day.

Treatment of children with this drug should be performed no longer than one week. Before taking the drug, you must consult a pediatrician.

Adverse Reactions

What are the undesirable consequences that can occur when taking an antibiotic, such as Alpha Normix? Side effects, reviews of which are extremely rare, with the use of this tool are infrequent. Of those that are available, most are associated with the symptoms of concomitant disease. So, some patients complain of high blood pressure, severe palpitation, dizziness, shortness of breath, headache, loss or distortion of taste, rash, fever, cold sweat, heartburn, diarrhea and Quincke's edema.

Most often, adverse reactions after taking the drug in question are manifested by the digestive system. To such undesirable phenomena include nausea, pain in the epigastric region and vomiting.

Reactions of this kind pass independently after a while after the initiation of therapy.

Signs of an overdose

What symptoms of overdose may occur if the medication "Alpha Normix" is not properly taken? According to the instructions, when using less than 2400 mg of rifaximin per day, an overdose is not possible.

If the patient has taken a dose that is significantly higher than the recommended dose, then he should necessarily rinse the stomach, as well as make symptomatic treatment.

Compatibility of antibiotic with other drugs

Experienced experts say that the interaction of this drug with other medicines is unlikely. This is due to the fact that the drug in question practically does not enter the systemic bloodstream. However, before using it, be sure to inform your doctor about what medicines you are using at this time.

Special recommendations on the use of the drug

What features of the drug should be known before taking the tablets or suspension of "Alpha Normix"? Reviews (analogues of this drug will be listed a little lower), experts report that it is extremely rare that this drug can enter the systemic circulation. As a rule, this happens when the intestinal mucosa is damaged. That is why this antibiotic is not allowed to use if there is an ulcer or erosion in the said organ.

If "Alpha Normix" got into the systemic bloodstream, then it can promote the staining of urine in a reddish-orange color.

Terms of sale, storage and expiration date

To purchase an oral antibiotic, you do not need a prescription. Granules and tablets "Alpha Normix" should be stored in a cool place inaccessible to small children.

The shelf life of this medication is three years. After the preparation of the suspension, it can be stored for one week, but only in a refrigerator. In the presence of an unpleasant odor, the solution should not be used.

Analogues and the cost of an antibiotic

Do you know about how much is the medication "Alpha Normix"? The price (reviews about this medicine will be presented right now) of this drug is quite high. This opinion is shared by many consumers.

Tablets in the amount of 12 pieces you can buy for 600-650 rubles. As for granules intended for preparation of drug suspension, they can be bought a little cheaper (for 550-570 rubles).

In the presence of contraindications to the use of the drug "Alpha Normix" it can be replaced by such drugs of a wide spectrum of action as "Rifaximin", "Nystatin", "Pimafucin", etc.

Feedback from consumers and experienced professionals

The patients' comments about the antibiotic in question are rather ambiguous. Some people report that this drug helped them cope with chronic bowel disease. By the way, it is often used as an effective emergency measure.

However, another category of patients recalls that after taking such strong antibiotics, you should definitely drink a course of probiotics. After all, this medicine is able to disrupt the normal microflora in the intestines, provoking a prolonged and intense diarrhea.

One can not help saying that among the negative responses very often there are reports that say that this drug has an overestimate value. Although experts say that the price of "Alpha Normix" fully corresponds to the quality of the medicine. Also, doctors say that for effective therapy, this drug should never be taken at its own discretion. It should appoint an experienced gastroenterologist, which for a long time is monitoring the patient's condition.