Lipid-lowering drug "Rosuvastatin": instructions for use

The drug "Rosuvastatin" instructions for use characterizes as a hypolipidemic drug from the group of statins. The action of this selective agent is based on the competitive inhibition of HMG-CoA reductase. As a result of the use of the drug "rosuvastatin" (the instruction for use confirms this), LDL catabolism increases several times, the liver LDL-C receptor index increases, and the number of VLDL decreases. As for the pharmacokinetic properties of this hypolipidemic drug, a pronounced therapeutic effect from its administration is observed seven days after the start of the course of therapy, reaching its maximum result in four weeks.

Take the tablets "Rosuvastatin" manufacturer recommends people suffering from a mixed form of hypercholesterolemia (type IIb) or hypercholesterolemia IIa (including heterozygous) as a supplement to the diet.

At the same time, this hypolipidemic drug is most effective when other methods of treatment (physical activity, weight loss) do not lead to the achievement of a proper therapeutic result. In addition, use the selective agent "Rosuvastatin" for use as an auxiliary drug during the treatment of homozygous family-type hypercholesterolemia.

It is strictly forbidden to prescribe these tablets if the patient has severe liver disease, myopathy, or severe renal dysfunction. During pregnancy, it is also not worth taking the lipid-lowering remedy Rosuvastatin. The medicine is contraindicated in the lactation period. In addition, it is not recommended to take these tablets simultaneously with cyclosporine or with increased sensitivity to their components. Persons who have not attained the age of eighteen years should also not use the selective agent "Rosuvastatin". Instructions for use do not recommend taking it in the case of alcohol dependence, established renal failure or liver disease.

With great caution use this lipid-lowering drug should people suffering from electrolyte, endocrine or metabolic disorders, hypothyroidism or arterial hypotension. With sepsis, uncontrolled epilepsy, proteinuria, extensive injuries and surgical interventions, it is also worth not to take the drug "Rosuvastatin". In addition, relative contraindications are hereditary muscle diseases and age over sixty-five years.

In conclusion, it should be said about possible side reactions, the appearance of which can be triggered by taking the "Rosuvastatin". For example, many patients complain of abdominal pain, constipation, dizziness and nausea. In addition, there is a small risk of myopathy, proteinuria, asthenic syndrome and myalgia.