"Differin", cream and gel: reviews. Analog "Differin"

The drug "Differin" is an excellent remedy for eliminating acne and other annoying skin defects. It is actively used in its practice by the most famous beauticians. But this medicine has a side effect - in the first days of application it can cause flaking and redness of the skin. This is a natural and transitory process, however, he repels some patients quickly. Of course, they are trying to find a remedy with a similar therapeutic effect and less pronounced side effects. But is it worth it and what drugs can replace the proven "Differin"? Reviews, analogues and other information about this tool you can learn from this article.

general characteristics

The drug "Differin" is a drug designed to combat acne. On the chemical structure it can be attributed to retinoids, and on pharmacological properties - to dermatoprotectors. This drug normalizes the metabolism in the skin, nourishes and protects it from the negative effects of the environment. The drug "Differin", analogues of which will be considered in this article, has the ability to control the rate of occurrence of epithelial cells, as well as the process of their keratinization and conversion into scales. In addition, it prevents the formation of hyperkeratosis (excess stratum corneum). Thus, this tool has an exceptional therapeutic and cosmetological effect. The drug "Differin" (gel or cream) can be used as a monotherapy against acne. It is also suitable for the treatment of acne in combination with other drugs.

Form of issue

The drug "Differin" in the modern market is produced in two dosage forms - gel and cream, having identical concentration of the main active component - 0.1%. They are sold in plastic tubes of 30 grams. The drug is manufactured by Pharmato French company Laboratoires GALDERMA, which focuses on the development and production of cosmetic products with healing effect. In the US and Europe, there is also a lotion "Differin", whose properties and active substance are identical to other products under this name.

The gel composition "Differin"

The main active substance of the drug "Differin", analogues of which will be listed below, is adapalene. In addition, as auxiliary components in the gel are usually added:

• Propylene glycol;
• Carbomer 980;
• Sodium hydrochloride ;
• Sodium edetate;
• Poloxamer 182;
• Phenoxyethanol;
• Methylparahydroxybenzoate;
• Distilled water.

Composition of cream "Differin"

The drug "Differin" (cream) contains in its composition a wide range of additional substances that give this dosage form the ability to moisturize and nourish the skin, due to which this agent dries out the skin much less than the gel. In addition to adapalena, it includes the following components:

• Polyethylene glycol-20;
• Carbomer 934P;
• glycerol;
• Methylparahydroxybenzoate;
• Perhydrosqualene natural;
• Sodium edetate;
• Propyl parahydroxybenzoate;
• Phenoxyethanol;
• Methylglucose sesquistearate;
• 10% sodium hydroxide solution;
• Distilled water;
• Cyclomethicone.

Therapeutic properties

The therapeutic effect of the drug "Differin" (cream and gel) is due to the properties of adapalene. This substance belongs to the retinoids of the last generation. It is a synthetic vitamin A in active form. The main therapeutic property of the drug "Differin" is the reduction in the number of skin rashes - comedones (black spots), acne, acne. It is able to reduce the amount of rashes and prevent the emergence of new due to the healing effect of adapalene on the body: sebostatic, comedogenic, anti-comedogenic, anti-inflammatory.

The sebostatic effect of this remedy is to reduce the production of sebum. Due to this, the fat content of the epidermis decreases significantly, the pores become much freer, and normal microcirculation is restored in the skin.

The anticommonotic and comedonolytic effects of the drug are interrelated and are due to the effect of the same mechanism. Adapalene has the ability to dissolve fatty plugs that clog pores, and also reduces the rate of formation of horny skin scales. This makes the drug "Differin" from black dots very effective.

The anti-inflammatory effect of the agent described by us is related to the ability of adapalene to neutralize the activity of the enzymes that cause this process.

Thus, the use of the drug "Differin" can significantly improve the appearance of the skin. However, the price of this drug is large enough, so some patients try to find a worthy replacement. As mentioned above, this product is manufactured by a French cosmetics company. Perhaps in Russia they produce cheaper, but at the same time not less than high-quality drugs? Let's analyze this question in detail.

Analogs and synonyms

It is well known that synonyms for a drug are drugs that contain the same active substance in their composition. But analogs are medicines with similar therapeutic properties, but different active components. The drug described by us has both.

Differin (gel) has the following synonyms:

• "Adapalen";
• "Clenzite";
• "Adolen".

Synonymous drug for another form of the drug is the cream "Adaklin".

Of course, in the modern pharmaceutical market there are also medicines with a similar therapeutic effect. Especially a lot of medications reminiscent of the effects on the body "Differin" (cream). The following preparations have similar properties:

• Ointment "Videestim";
• Ointment "Radevit";
• Retinoic ointment.

Each of these tools has its advantages. Usually, the owners of dry skin use fatty creams and ointments, because they need constant moistening. However, most patients with fatty epidermis suffer from fatty epidermis. It is preferable to apply them for the treatment of skin "Differin" -gel. A similar effect on the body is provided by the means listed below:

• Gel "Isotrexin";
• Solution "Retasol".
• Gel "Effezel".

In addition, there are drugs that, strictly speaking, can not be attributed to either synonyms or analogues of "Differin". However, they are also designed to combat acne and are effectively used in both monotherapy and in combination with other medicines. These are, for example, "Baziron" and "Skinoren." Which of these tools is better? Everyone should answer this question for himself, because the body of any person is individual. Let us dwell on the description of some means in more detail.

"Clenzite" or "Differin"?

These drugs are synonymous, that is, both contain adapalene. However, the original "Differin" is produced in France, and the generic "Clenzite" is produced in India. Therefore, these medicines have different degrees of effectiveness. The analogue of "Differin" in some patients raises enthusiastic reviews, and the other does not help at all. After all, generics are the means in which there are the same active substances as in the original medicines, but the technology of their manufacture can be very diverse. In addition, the purity of the chemical compound in the original preparation and analogue can also vary. Therefore, if you want you can try a cheaper "Clenzite", but if its application seems ineffective - it's better to go to "Differin".

Skinoren or Differin?

"Skinoren", as well as "Differin", is available in two dosage forms - gel and cream. By and large it is ineffective. This analogue of "Differin" deserves attention because it is often used for maintenance therapy after treatment with other medicines. For example, after a course of treatment with the drug "Differin" for three months, experts recommend switching to a weaker "Skinoren", which should be used for preventive purposes several times a week. In this case, patients can find, so to speak, a marble complexion, since the medicine has a whitening property. In addition to this effect, this drug has virtually no side effects.

"Baziron" or "Differin"?

Basically, Baziron is not an analog of Differin, because these drugs have different mechanisms of action. Even the therapeutic effect of them is somewhat different. Cream "Baziron" struggles with external manifestations - removes inflammation, eliminates bacteria and thereby reduces the number of comedones and acne. The drug "Differin" from black dots also helps, but it struggles with the causes of acne: it reduces the production of sebum, releases pores from it, reduces the amount of horny skin, improves its breathing and microcirculation, preventing the multiplication of inflammatory microbes in it. Both medicines can provoke irritation, but this effect is still more pronounced in Baziron.

Thus, an effective and safe "Differin" is the most suitable option. However, often these two drugs are used together. Cosmetologists recommend in the morning to apply cream "Baziron" to the skin, and in the evenings to use "Differin". The effectiveness of such a combination is very high, but when used, there is a risk of excessive drying of the skin and even a burn. Therefore, in the presence of severe inflammation, it is better to use "Baziron", and then go to "Differin".

The magic "Radevit"

The drug "Radevit" is a worthy analogue of "Differin" in Russia. It can be used both for the care of healthy skin, and for healing from various epidermal diseases. The spectrum of its use is very wide:

• Restoration of the skin after a burn, including sunburn;
• Removal of peeling and dryness after insolation;
• Prevention of photoaging;
• Adaptation of the skin to climate change;
• Prevention of the epidermis from the negative influence of the environment (smoke, smog);
• Increase immunity in adults.

The therapeutic effectiveness of this drug is due to the composition of the above drug. It contains vitamins D, E, A. They have a beneficial effect on the skin and effectively stimulate the production of collagen, ensuring its elasticity.

So, "Differin" is effective only if it is used to regulate the work of the sebaceous glands in the skin and eliminate black spots and acne. And the drug "Radevit" has a wider range of effects, but to eliminate acne it is usually not used. It would seem that these two drugs complement each other, but they should not be used together. The fact that "Radevit" in no case can not be used with other retinoids in order to avoid their excessive accumulation in the body.

Reviews

In the overwhelming majority of cases, reviews about the drug "Differin" are positive, as it has a high efficiency, it really removes acne and improves the skin condition of the face. However, there is a negative point - this cosmetic product in the first weeks of use causes painful redness and peeling. Over time, the above phenomena disappear, and the skin condition improves significantly. However, some patients do not withstand psychological stress and start looking for an analogue of "Differin".

Positive opinion about this drug is supported by the ability to use it for the treatment of acne, black spots and acne, and as a retinoic peel. In rare cases, "Differin" causes intense irritation, which causes people to stop using it. This fact creates negative opinions about it in individual patients, and as a result, we have negative feedback.

Now you know what the drug "Differin" is and what drugs it can replace. However, when choosing the right remedy, it is better to consult a competent cosmetologist.