Ursofalk: instructions for use

The drug "Ursofalk" is a hepatoprotector, which has a very broad spectrum of action. The drug is able to have not only hepatoprotective, but also cholelitholytic and immunomodulating action. In addition, it leads to a decrease in the level of cholesterol in the blood.

The main active substance of ursofalk is ursodeoxycholic acid, which is present in the bile. With certain violations, the synthesis of this acid is reduced. The mechanisms of matter are very diverse, so we will single out only the main ones. The meaning of the choleretic action is to regulate the amount of hydrophobic bile acids and increase their excretion into the intestine. So, the drug reduces the absorption of toxic hydrophobic acids in the bile. The cytoprotective effect is based on the ability of the active component to be incorporated into the lipid layer of the cell membrane. This stabilizes the cell membrane and improves its protective properties. The effect of ursophane as an immunomodulating agent is due to the fact that ursodeoxycholic acid reduces the expression of certain molecules on hepatocytes, as well as pro-inflammatory cytokines.

In addition, ursodeoxycholic acid reduces the lithogenicity of bile by forming liquid crystals with the cholesterol molecule.

Ursofalk: instruction (evidence)

The drug is prescribed for the treatment of various diseases of the gallbladder and liver, which are accompanied by an increased level of cholesterol in the blood, cholestasis and a decrease in the function of the liver. Ursofalk is used in primary biliary cirrhosis, sclerosing cholangitis, various forms of hepatitis, the presence of cholesterol stones in the gallbladder, cystic fibrosis, toxic liver damage, liver diseases with cholestasis in childhood.

The drug is also taken to eliminate stagnation of bile in patients who are on parenteral nutrition, as well as those who suffered a liver transplant. Ursofalk is often prescribed for the prevention of liver damage when taking various cholestatic drugs, as well as for the prevention of colon cancer in patients who are at risk.

Ursofalk: instructions (how to use and dosage)

This medicine is taken orally. If the drug is taken once, it is recommended to take it in the evening. Capsules are taken entirely without chewing. As a rule, they are washed down with water. Patients with difficulty swallowing and children the drug is administered in the form of a suspension.

The course of treatment itself, its duration and dosage are determined by the attending doctor on an individual basis, taking into account the peculiarities of each individual case. Usually patients with liver diseases are prescribed Ursofalk drug at a daily dose of 10 to 15 mg per kg of body weight. The standard duration of the course of treatment is from six months to two years.

Ursofalk: instruction (contraindications and side effects)

Contraindications:

- hypersensitivity to certain components of the drug;

- acute form of cholecystitis or cholangitis;

- biliary colic, violation of the motor activity of the gallbladder directly;

- confirmed gallstones gallstones.

With regard to pregnancy, it is established that ursodeoxycholic acid is able to penetrate the placenta, but there is no more detailed information on its effect on the fetus. Therefore, the need to prescribe the drug to pregnant women is determined by a specialist.

The drug is well tolerated.

Ursofalk instructions (additional information)

To date, there is no information about an overdose.

The drug is stored in a dark dry place at a temperature of no more than 25 degrees Celsius for not more than five years.

Attention! This instruction is intended for superficial familiarization with the preparation and its properties. The information provided should not affect the decision on the use of Ursofalk or its cancellation.