Glandular cystic endometrial hyperplasia

In 25% of women who are examined for infertility, endometrial hyperplasia is diagnosed. It is the overgrowth of the uterine mucosa. This disease is dangerous because it can eventually turn into cancer.

One of its variants is glandular-cystic hyperplasia of the endometrium. This form of the disease leads to cancer with less probability than atypical and is better treatable. However, it is the next stage in the development of the disease after glandular hyperplasia. There is also a focal form in which a glandular fibrous, fibrous or glandular polyp of the endometrium is formed, whose treatment is usually surgical. Quite often it does not form one.

If suspected of hyperplasia, scraping is performed for diagnostic and therapeutic purposes. First, during the manipulation, the enlarged endometrium, including the polyps, is removed. Secondly, the obtained material is sent to a histology, with the help of which the type of hyperplasia is determined.

Today, scraping is increasingly performed under the supervision of hysteroscopy. Its use reduces the likelihood of complications to a minimum and significantly increases the efficiency of manipulation, since it is performed under the control of the eye.

Most women who have experienced this disease are interested in how the glandular cystic hyperplasia of the endometrium affects the onset of pregnancy. Experts argue that conception with this disease is not ruled out, but it is problematic and undesirable.

The fact is, the cause of hyperplasia is an increased amount of estrogen and / or a lack of progesterone. This occurs when the balance of hormones is impaired as a result of various diseases and / or a prolonged absence of ovulation.

Estrogens, which are released by the maturing follicle, stimulate the growth of the uterine mucosa. After ovulation, a yellow body forms in its place, which synthesizes progesterone. This hormone has an opposite effect on the endometrium and prepares it for implantation of the embryo.

With prolonged absence of ovulation, progesterone is not excreted. Against this background, there is a glandular cystic hyperplasia of the endometrium. However, it is often the result of a high level of estrogen in the body.

This occurs with inadequate hormone therapy, ovarian tumors, obesity and a number of other diseases. As a result of research, it is established that fatty tissue is capable of secreting estrogens, especially if there are a lot of it.

Against the background of hormonal disorders, and especially the absence of ovulation, pregnancy becomes extremely problematic. In addition, embryo implantation in the altered endometrium also occurs with difficulty.

It is established that pregnancy accelerates the transition of a benign neoplasm to a malignant tumor. Therefore, pregnancy against a background of hyperplasia is highly undesirable.

However, after treatment, women with this disease give birth to healthy babies. Therefore, glandular cystic hyperplasia of the endometrium, the treatment of which consists of curettage and hormone therapy, is not an obstacle to maternity.

The patient should take the medications chosen by her individually gynecologist-endocrinologist for six months. Results of therapy are controlled by ultrasound, biopsy, scraping.

Among the hormonal drugs used are gestagens, COCs, medicines that cause an artificial menopause. Their choice and the scheme of reception depends on accompanying diseases, the age of the patient, the desire to become pregnant, weight and a number of other factors.

Sometimes in nulliparous patients, the doctor can try to do without scraping. However, if there is no result of hormone therapy, it will still have to be done.

Thus, glandular cystic endometrial hyperplasia is dangerous because it can lead to cancer and infertility. After successful treatment, the prognosis is favorable.