The drug 'Depakin-chrono 300'. Reviews, description

The drug "Depakin-chrono 300" is manufactured in tablets that have a prolonged (prolonged) effect. The drug is included in the category of antiepileptic drugs.

Tablets "Depakin-chrono 300" instruction recommends taking with food, not crushing. Preferably, the daily dose is divided by two times. A single use of the drug "Depakin-chrono 300" (expert reviews indicate this) is allowed only with controlled epilepsy.

The drug differs from other drugs in its group by the delayed release of the active ingredient. This, in turn, leads to a decrease in the maximum concentration of the active component and contributes to a more even distribution throughout the body throughout the day.

Means "Depakin-chrono 300" (the doctors' reviews are the same) are allowed for adults and children whose body weight is more than seventeen kilograms. This dosage form is not recommended for patients under six years of age. The preparation "Depakin-chronosphere" was developed for young children. The medication is also available in a suspended form.

The optimal initial dosage of the drug "Depakin-chrono 300" (specialists' testimonials testify to this) per day is from ten to fifteen milligrams per kilogram. Subsequently, the amount of the agent is increased.

On average, the dosage per day is twenty to thirty milligrams per kilogram. In the absence of control over epilepsy at this dose, the amount of medicine may be increased. The patient should be supervised by a doctor.

For the elderly, the dosage is set in accordance with the clinical picture. Despite the fact that the amount of the drug is calculated taking into account the weight of the patient, it is necessary to take into account the individual tolerability of the active component of the agent (valproate).

The drug "Depakin-chrono 300" (reviews of doctors and patients testify about this) is transferred, in general, well. However, side reactions are not excluded. When using medicament for all undesirable manifestations, it is necessary to inform the doctor immediately. The drug "Depkin-chrono" can provoke cognitive impairment with the development of dementia. These disorders are eliminated for several weeks or months from the last reception.

In some cases, the drug "Depakin-chrono" can cause lethargy or stupor, resulting in a coma (transitory). With a reduction in dosage or withdrawal of the drug, these reactions were eliminated.

Very rarely during the course of therapy, development of parkinsonism was noted.

In some cases, the drug "Depakin-chrono" can cause headache, drowsiness, postural tremor (easy), gastralgia, vomiting. Side effects include also disorders of the liver, pancreatitis, requiring discontinuation of therapy, pancytopenia, leukopenia, anemia.

When taking the medicine, allergic reactions are likely, erythema multiforme, vasculitis, urticaria, epidermal necrolysis (toxic), rash.

In some cases, there may be a change in body weight, hearing loss (irreversible and reversible), disruption of the menstrual cycle and amenorrhea.

Contraindicated in the drug "Depakin-chrono" with hepatitis (acute and chronic), children under six years of age, with pregnancy, lactation, with hypersensitivity.

It is not recommended simultaneous use of the drug with medicines "Meflokhin", "Lamotrigine."

The transition from other antiepileptic drugs to the drug "Depakin-chrono" should be carried out gradually under the supervision of a doctor, reaching the optimal dosage for at least two weeks. Together with this, taking into account the patient's condition, reduce the amount of the previous medication.