Furazolidone instructions for use.

Name of drug:

"Furazolidon" (latin.Furazolidonum).

The form of release: tablets on five hundredths grammes in plates on ten pieces.

Pharmacological properties of the drug "Furazolidon" instructions for use describes this:

This drug refers to antibacterial drugs from the group of nitrofurans. It is a synthetic derivative of 5-nitrofurfurol, with pronounced antimicrobial activity, especially against aerobic gram-negative microorganisms. Gram-positive aerobes, fungi and some species of protozoa possess less sensitivity to this drug. Pharmacological action depends on its dose: in the case of low doses, the effect of "Furazolidon" is bacteriostatic, and when the dose is increased, its bactericidal activity is manifested. In addition, the drug stimulates the human immune system. The stoppage of the development of the microbial cell and its further elimination is due to the fact that this medication is able to disrupt the integrity of the cell membrane and its structure, disrupt their cellular respiration, function of the cytoplasmic membrane, and synthesize a number of proteins. Stimulation of immunity is due to the fact that "Furazolidon" is able to stimulate the activity of leukocytes in the performance of their phagocytic function and increase the complement titer. In addition, the drug is able to reduce the production of toxins by microbes, which causes an improvement in the general condition of patients even earlier than the negative result of microbiological tests. Resistance to the drug in microorganisms develops, but extremely slowly.

Furazolidone. Application.

For the treatment of patients suffering from infections of the urogenital organs, gastrointestinal tract, skin, for example, such as typhoid, bacillary dysentery, enterocolitis, paratyphus, infectious diarrhea, giardiasis, food poisoning, trichomoniasis (in particular, trichomonas colpitis), urethritis, vaginitis, pyelitis and cystitis. Also, this drug is used to sanitize infected burns and wounds.

Furazolidone tablets. Application. It is taken orally after eating, is swallowed whole, chew and grind it is not necessary, drink a large amount of water. Doses and the period of admission are determined by the doctor, individually for each patient, taking into account his personal characteristics and the nature of the disease. To treat infections of the gastrointestinal tract to adults, "Furazolidon" instructions for use recommends that one-tenth and one-tenth grams (two to three tablets) be administered four times a day for a duration of five to ten days. There is a cyclic scheme of taking the drug: one - one and a half tenths of a gram four times a day for three to six days, then a break for three to four days and a repetition of the previous cycle. With giardiasis adults - two tablets four times a day. When trichomonadnoe urethritis adults - two tablets, four times a day - three days. With trichomonias colpitis adults - two tablets three - four times per day, in combination with other drugs, in the form of rectal and vaginal suppositories containing "Furazolidone." The total duration of the course is one to two weeks, and the oral intake is three days. For children suffering from dysentery, food-borne diseases and paratyphies, the dose of the drug "Furazolidone" recommends the use of the instructions in accordance with their weight and age. The maximum duration of admission is ten days. For the treatment of infected burns and wounds, the drug is prescribed in the form of wet-drying dressings or irrigation with a solution at a concentration of 1: 25,000.

With the side effect of the drug "Furazolidone", the instructions for use describe the following conditions:

Anorexia, vomiting, nausea, epigastric pain, allergies. In the case of prolonged use, hemolytic anemia, dyspnea, hyperthermia, neurotoxic reactions may develop.

Contraindications to the drug "Furazolidon" an abstract to it is given by:

Hypersensitivity to its components, terminal stage with renal failure, age less than a year, pregnancy, lactation, liver disease, nervous system.