Gentamicin. Instructions for use.

Did the doctor prescribe the antibiotic Gentamicin? The instruction for the use of the preparation describes in detail all cases of the use of this drug.

"Gentamicin" refers to antimicrobial and antiparasitic agents. This antibiotic is produced by the fungi Micromonospora purpurea. A mixture of gentamicin types C1, C2, C1a is called "gentamycin sulfate". The instruction for "Gentamycin" and "Gentamycin sulfate" is identical. This preparation has the appearance of a white powder or a porous mass with a cream tinge. It dissolves easily in water. In alcohol, the drug is practically insoluble. It is classified as aminoglycoside antibiotics.

The drug has a bacteriostatic effect on Proteus, Escherichia coli, Salmonella, Staphylococcus and other bacteria. Resistance of microorganisms develops slowly enough. Drug-resistant "Kanamycin" and "Neomycin" strains are also resistant to this antibiotic. Bactericidal concentration after ingestion of the drug into the body is created in an hour and remains up to 12 hours.

Antibiotic "Gentamycin", instructions for use

Assign this prearat for various infectious diseases (pleurisy, pneumonia, empyema, bronchopneumonia, peritonitis, meningitis, urethritis, wound infection, septicemia, chronic pyelonephritis, cystitis). The drug is effective in prostatitis. In cases of severe purulent infections and mixed infections, the drug "Gentamicin" is also prescribed. Instructions for use allow in this case, its combination with medicines "Carbenicillin" or "Ampicillin" (semisynthetic penicillins). In some severe cases, it is effective with insufficient activity of other antibiotics.

Method of application: intravenously (drip), intramuscularly, topically. A single minimum dose of 0.4 μ / kg. The daily maximum dose for severe cases is 5 mg / kg. Daily doses of the drug vary. The dose of the drug depends on the type of disease and its severity, the patient's body weight and age. Children under 14 years of age are prescribed antibiotic according to vital indications. The daily dose, as a rule, is divided into 2 times, although it is possible to divide it by 3 times. The average duration of the drug is 7-10 days. The intravenous antibiotic is administered no more than 3 days and, in the future, is switched to intramuscular injections.

For infections of the respiratory tract this antibiotic is often used for inhalations (0.1%). In keratitis, conjunctivitis and other eye infections 3-4 times a day, a few drops are injected into the eyes with a 0.3% solution of gentamicin. Ointment "Gentamycin-AKOS", the instruction: it is applied at folliculitis, pyoderma, furunculosis. It contains 0.1% gentamycin sulfate. Affected areas are lubricated daily 2-3 times. Such procedures should be conducted 7-14 days.

The drug is produced in such forms: in ampoules with 4% solution (1, 2 ml), in the form of powder in flacon (0.08 g), in tubes with 0.1% ointment (10, 15 g), eye drops in tubes Drippers with 0.3% solution.

Side effects and contraindications

Effective antibiotic "Gentamycin", the instruction for its use promises the destruction of many microorganisms, can cause the patient's health not only good, but also tangible harm. Self-medication is unacceptable. When prescribing a medicine, the doctor must take into account that this antibiotic can have a nephrotoxic and ototoxic effect. This drug is contraindicated in neuritis of the auditory nerve. It is inadmissible to use this medication simultaneously with other antibiotics, especially those that also have nephro- and ototoxic effects. The prescription of the drug "Gentamicin" to pregnant women is carried out only according to vital indications. When violations of excretory functions of the kidneys, it is used with extreme caution (in small doses). With severe dysfunction of the kidneys and uremia, it generally can not be prescribed. This antibiotic has the ability to block nerve and muscle conduction and can act as a curare-like drug. Before applying the drug, it is best to make a test for the reaction of the body and if the injection site turns red and swollen, it is better to refuse treatment with Gentamicin.