The medicine "5-NOC". Instructions for use

Today, it is often possible to find a number of drugs with different names and, at the same time, containing the same active substance in their composition. A vivid example of this is the antibacterial "5-NOC" having many analogues. Instructions for use indicate the antifungal and antiprotozoal effect of this agent.

This medicine belongs to the group of oxyquinolines. The main active substance, nitroxoline, is found in several other medicines. For example, in such as Nitroxolin, Nitroxolin-UBF, Nitroxolin-AKOS, produced by domestic pharmaceutical companies, and therefore having a lower price than the 5-NOK medicine produced by the Slovenian company LEK.

When using the "5-NOK" preparation, selective inhibition of DNA synthesis inside microorganism cells takes place, which prevents them from multiplying (the so-called bacteriostatic effect). Nitroxoline adversely affects a wide range of microorganisms, including strains capable of resisting the action of various antimicrobial agents, which belong to other groups of drugs.

Some fungi, including fungi of the genus Candida, mold fungi, dermatophytes, as well as those that cause deep mycoses (up to the inflammatory process), can be neutralized and destroyed with the help of the preparation "5-NOC". Instruction for use notes that this drug is able to reduce the adhesion of uropathogenic cells to the epithelial ball of the urinary tract.

What is the use of the "5-NOC" tool ?

The medicine, about the features of its application, is mainly prescribed for infectious (both chronic and acute) diseases of the urinary system, which can be caused by bacteria and microorganisms sensitive to the action of "5-NOC". Instructions for use also indicate that this tool can be used for prevention. That is, in order to prevent infectious diseases of the kidneys and other organs of the urinary system during therapeutic manipulation and diagnosis, and also in the postoperative period, especially after operations on the bladder, kidney and urinary tract, catheterization and cystoscopy.

Various sources indicate that "5-NOC" is an antibacterial or antimicrobial chemotherapy. In this regard, patients often ask a question, is the "5-NOC" medication an antibiotic or not? Opinions of doctors on this issue diverge. However, as already mentioned, this drug has a bactericidal effect on microorganisms, blocking their metabolism and thereby causing their death.

Like any drug, the drug "5-NOC" has both contraindications and side effects .

Of course, the drug is not prescribed to those who are sensitive to its components. The sensitivity to the derivatives of 8-hydroxyquinolines is also a contraindication to taking the "5-NOC" medication. Instruction for use determines as contraindications as cataract, pregnancy and, of course, the period of breastfeeding.

Patients with violations of the liver and kidneys drug "5-NOC" is also not appointed.

Children under the age of three this pharmaceutical product is appointed in extreme cases, when treatment with other drugs is already ineffective.

During the application of the drug "5-NOC", some side effects may appear. For example, some violations of the liver, nausea, anorexia, vomiting, tachycardia, dizziness, headache. Polyneuropathy can also occur, and in some cases, coordination of movements may be impaired. With prolonged use of the drug "5-NOC" there is a possibility of a negative effect on the optic nerve.

Also, various allergic reactions are possible: itching, skin rash and hives. However, all the side effects that occur during the use of the "5-NOC" medication, usually occur after the drug is discontinued.

The duration of the course of treatment and the dosage of the drug is determined by the attending physician on an individual basis.

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