Novobismol preparation: instructions for use, analogues, price and reviews

Ulcerative diseases of the digestive tract appear for various reasons. However, such diseases are always treated the same. Along with proper nutrition, intake of enzyme preparations and inhibitors of H + -K + -ATPase, doctors must include in the regimen of therapy and antiulcer drugs. One of these medicines is Novobismol. The price of this medicine, its properties, indications, methods of application, analogues and contraindications will be considered in this article.

Description, composition, shape and packaging

What does Novobismol contain? Instruction for use informs that the active substance of this medication is bismuth titrate dicitrate. Potassium polyacrylate, corn starch, povidone K 30, magnesium stearate and macrogol 6000 are used as auxiliary components.

On sale round biconvex tablets of creamy white color without any smell come in contour cells, placed in cardboard boxes.

Pharmacology of a medicinal product

What are Novobismall tablets? The instructions for use indicate that this is an antiulcer drug with bactericidal activity against Helikobakter Pilori. It has astringent and anti-inflammatory effect.

In the acidic environment of the stomach, the medicament forms insoluble bismuth citrate and oxychloride, as well as chelate compounds in the form of a protective film on the surface of erosions and ulcers.

Increasing the formation of mucus, the synthesis of prostaglandin E and the secretion of bicarbonate, this drug activates the cytoprotective mechanisms, increases the resistance of the gastrointestinal mucosa to the effects of hydrochloric acid, pepsin, enzymes and bile acids. It also accumulates epidermal growth factor in the defect zone, reduces the activity of pepsinogen and pepsin.

Pharmacokinetics

What kinetic properties are inherent in Novobysmol tablets? Instructions for use (the price of the medication is listed below) states that bismuth tricalium dicitrate is almost not absorbed from the digestive tract. Although in some cases an insignificant amount of this substance can still enter the systemic circulation.

The drug is mainly taken with the feces. A small part of bismuth, which enters the plasma, is excreted by the kidneys.

Indications

What diseases treats the drug "Novobismol"? Experts say that this medicine is effective for peptic ulcer diseases in the phase of exacerbation (including those associated with Helikobakter Pilori).

Also, the drug is prescribed for chronic gastritis and gastroduodenitis in the phase of exacerbation, irritable bowel syndrome, which proceeds mainly with signs of diarrhea, functional dyspepsia, not associated with organic gastrointestinal diseases.

Contraindications

What conditions of the patient prohibit the use of Novobismol? The instructions for use suggest that this remedy should not be administered if there is a marked disruption in the kidney function, during breastfeeding, with increased sensitivity to bismuth tricalium dicitrate and during pregnancy.

Dosage and route of administration

How should I use Novobismall medication? Instruction for use informs that this tool is prescribed not only for adults, but also for small patients, starting from the age of 4.

Tablets are taken orally 2-4 times a day exactly 30 minutes before eating. The dosage of the drug is selected individually. As a rule, it depends on the age of the patient.

The course of treatment is 4-8 weeks. In the next 8 weeks, it is strictly forbidden to take drugs that also contain bismuth.

To eliminate Helicobacter pylori tablets "Novobismol" is advisable to use in combination with antibacterial drugs that have anti-Helicobacter activity.

Adverse events

Does Novobismol medication have side effects? The patients' reviews say that after taking these tablets, they often have undesirable effects. From the side of the digestive tract, the patient develops transient effects such as nausea, frequent stools, vomiting, or constipation. Dermatological reactions can also occur in the form of skin rashes and itching.

With prolonged use, especially at high dosages, the patient can develop encephalopathy from the central nervous system, which is associated with the accumulation of bismuth in the central nervous system.

Joint intake of the drug with food

When the drug is combined with other medicines, as well as with food and liquids, including antacids, milk, fruits and fruit juices, the efficiency of bismuth tricalium dicitrate may change for the worse. Therefore, the tablets should be taken exactly half an hour before meals, liquid or other drugs.

Special Recommendations

It is strictly forbidden to take Novobispol medicament for more than 2 months in a row.

During the therapy, it is highly recommended not to exceed recommended daily dosages for adults and young children.

At the end of the course treatment, the concentration of the active ingredient in the blood plasma does not usually exceed 5-60 μg / l, and intoxication is observed only at 100 μg / l and more.

Against the background of the application of the means under consideration, it is possible to stain the feces in a dark color. In rare cases, there is a slight darkening of the tongue.

Novobismol: analogues and cost

Structural analogues of this remedy are: "De Nol" and "Ventrisol". Similar drugs for the pharmacological group include: "Ankrusal", "Alsukrul", "Venter", "Kaopectat", "Rebambid Macleodz", etc.

How much does the Novobispol drug cost? The price of this medicine varies between 550-600 rubles per 112 tablets.

Customer Reviews

The majority of patients who used the drug in question, speak about it positively. They argue that this medication contributed to the rapid elimination of peptic ulcer and complete recovery. However, some patients note that after taking this remedy, they almost immediately had side effects, and therefore they were forced to stop treatment.