Health, Preparations
"Miniziston": reviews and analogues
For someone, pregnancy can be a joyful and long-awaited event, and for some couples - a complete surprise. Therefore, a woman who is not yet planning to become a mother, should be protected from unwanted pregnancy. Modern medicine offers a huge selection of all kinds of contraceptives. One such effective means is the preparation "Miniziston". Reviews of women about the drug can be heard at most positive.
Form release, composition and packaging of tablets
"Miniziston" is a monophasic contraceptive for oral administration. Produced in the form of tablets in pink. The active ingredients in the composition are ethinyl estradiol and levonorgestrel. Auxiliary components:
- corn starch;
- Lactose monohydrate;
- Povidone;
- Magnesium stearate;
- Calcium carbonate;
- Stearose;
- Red iron dioxide dye;
- Wax mountain glycolic.
pharmachologic effect
Combined monophasic contraceptive for oral administration. The contraceptive effect of the preparation "Miniziston 20" is based on the complex action of various factors, the most important of which are oppression of ovulation and a change in the viscosity of the cervical mucus.
- Normalize the menstrual cycle.
- Reduce pain during critical days.
- Menstrual flow is not so abundant as to help reduce the risk of anemia.
Nowadays the most popular and popular among gynecologists and their patients is the medicine "Miniziston". Reviews about the drug are positive, as it does not harm the body and is available in the application.
Levonorgestrel
After ingestion, the substance levonorgestrel in a short time and completely absorbed. In serum, the maximum amount of the drug is reached within an hour. Here, levonorgestrel combines with albumin and globulin, which binds the sex hormones.
With daily intake, the substance accumulates in the second phase of excretion and reaches its maximum already on the 4th day. Pharmacokinetics directly depends on the concentration of hormones in the blood plasma. Due to the fact that there is ethinyl estradiol in the composition, the hormone content rises by almost 70% with the intake of the Miniziston 20 fem. Medication. The doctors' comments on the medicine will help the patient make the right choice of contraceptive pills to avoid an unplanned pregnancy.
Levonogestrol is excreted unchanged. His metabolites within a day go with urine. The concentration of the drug in the plasma is reduced in two stages. The first period takes half an hour, and the second takes 20 hours.
Ethinylestradiol
When ingested, rapid absorption occurs. After 2 hours, the maximum concentration in the blood is reached. In the liver, the substance is metabolized. Ethinylestradiol is almost 100% bound to albumin. In blood, the concentration of the agent is reduced in two stages. The first period takes about an hour, the second - 10 or 20 hours. Completely eliminated from the body. Metabolites come out within 24 hours.
Indications and contraindications
The preparation "Miniziston" is indicated for the prevention of pregnancy. The responses of experts show that the medicine has a number of contraindications. Do not prescribe a contraceptive in the following cases:
- If the patient has acute or chronic arterial or venous thrombosis.
- When there is a tendency to thrombosis in anamnesis or at a given time. For example, transient ischemic impairment of cerebral circulation.
- The presence of diabetes mellitus, complicated by violations of the cardiovascular system.
- Tumors of genital organs or mammary glands hormone-dependent.
- Unreasonable vaginal bleeding.
- Fruit bearing.
- Breast-feeding.
- Benign or malignant liver tumors.
- Hypersensitivity to the components of the drug.
Dosage
Take the medicine on an ongoing basis in the order shown on the package. Tablets should be washed down with a small amount of water. Before use, the "Miniziston" preparation instruction must be studied. The feedback from specialists shows that the regimen is determined by the duration of the menstrual cycle.
Overdose
There is no information about an overdose of the drug. In exceptional cases, slight intoxication can occur, which is expressed by nausea and vomiting. When these symptoms appear, detoxification therapy is performed and the stomach is washed.
Interaction with other drugs
With the joint administration of the drug "Miniziston" with drugs that induce microsomal enzymes of the liver, the clearance of ethinyl estradiol and levonorgesterol can increase, which will make contraception ineffective and can lead to bleeding. There are also a number of drugs that can not be taken together with the medicine Miniziston. These include:
- "Oxcarbazepine";
- "Topiramat";
- Felbamate;
- Ampicillin;
- "Tetracycline";
- Rifampicin.
Pregnancy and the period of breastfeeding
If the pregnancy is detected when taking the drug, it is immediately canceled and later not accepted. According to statistics, no child was injured when taking the contraceptive at an early stage of pregnancy, when it was not yet identified.
Side effects
Basically, the drug is well tolerated, but in exceptional cases, the following symptoms may occur:
- nausea;
- Vomiting;
- Changes in vaginal secretion;
- Changes in the mammary glands: swelling, tenderness, swelling, discharge from the nipples;
- Increase in body weight; Decreased sexual desire;
- Pain in the head, migraine;
- allergy;
- Edema;
- Chloasma.
special instructions
Only a doctor can prescribe pills "Miniziston". The reviews show that without the recommendation of a specialist, most women take the medicine incorrectly.
The patient should be informed that with the development of symptoms of venous or arterial thrombosis, the doctor should be consulted.
Prohibited reception of funds for severe liver and kidney pathology, as well as jaundice. Keep the medicine in a cool and dark place, away from small children. Before you start taking it, carefully read the instructions and the completion date on the package.
If the contraceptive was not found in the pharmacy, the specialist will be able to recommend a qualitative analogue. The most popular substitutes will be described below.
"Microgonon"
Monophasic contraceptive for oral administration. Produced in the form of a dragée. The main substances in the remedy are ethinyl estradiol and levonorgestrel.
- Oppression of ovulation at the level of hypothalamic-pituitary regulation;
- A change in the viscosity of the cervical mucus, as a result of which spermatozoa can not penetrate into the uterine cavity;
- Change in the endometrium, which does not allow a fertilized egg to settle in the uterus;
- Normalization of menstruation, painlessness and reduction of bloody discharge.
Indications and contraindications
The drug is prescribed as a contraceptive. There are contraindications for its reception:
- diabetes;
- Various thromboses of acute and chronic nature;
- Frequent headaches;
- Pancreatitis;
- Hepatic and renal insufficiency and some other conditions.
Before the beginning of treatment should be studied, as in the case of tablets "Miniziston", the instruction. Reviews show that side effects are most often the result of improper use of the drug.
Dosage
The packaging shows the sequence of the dragees. Take one tablet a day. Drinking a medication is necessary 21 days, the next course begins after a 7-day break. During this period, menstrual bleeding occurs.
Side effects:
- Spotting spotting;
- nausea;
- Vomiting;
- Weight gain;
- Soreness and swelling of the mammary glands;
- allergy.
In the pharmacy, the medicine is dispensed on prescription. You can not prescribe a remedy for severe liver and kidney pathology. Keep the dragees away from children, in a cool and dry place.
Oralcon
This drug can also replace tablets "Miniziston." Experts' reviews show that the drugs do not differ in composition and have a similar effect on the female body. Oralcon is a monophasic oral contraceptive. Produced in the form of white tablets. The main components of the drug are levonorgestrel and ethinyl estradiol.
- Oppresses ovulation.
- Increases the viscosity of the cervical mucus, which prevents penetration of the sperm into the uterus.
- Normalizes the cycle.
- Critical days pass without increased blood loss and pain.
Indications and contraindications
The drug is indicated to prevent unwanted pregnancy. He is also prescribed for hormone-dependent disorders of the monthly cycle. The agent has the same actions as the preparation Miniziston. The doctors' testimonies testify that among the patients the medicines are equally popular.
Do not prescribe the drug "Oralcon" with the following diseases:
- Signs of venous or arterial thrombosis;
- diabetes;
- Vascular disorders;
- Renal and hepatic impairment;
- Neurological pathologies;
- pregnancy;
- breast-feeding;
- Bleeding of unknown origin;
- Hypersensitivity to the drug.
"Oralcon" has the same contraindications to admission, as well as tablets "Miniziston 20".
Feedback indicates that oral contraceptives can become a reliable advocate against unwanted pregnancy. Miniziston, as well as its analogs (Oralcon, Microgonon, Antevin, Ovidon, Tri-Regol) are quite effective. But to protect yourself from sexually transmitted diseases, using pills will not succeed.
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