Testosterone undecanoate: instructions, analogues and reviews

Testosterone undecanoate is an ester of natural androgen, testosterone. About the form in which this tool is released, for what and how it is used, we will tell in the article presented.

Also you will find out what properties this substance has, whether it has contraindications and side effects.

Form of release, description and packaging

Testosterone undecanoate goes on sale in various forms:

• Gelatin capsules, which contain the active substance. They are packed in blisters and cardboard boxes respectively.
• An oily and clear solution with a yellowish hue for intramuscular injection. 1 ml of this drug contains 250 mg of testosterone undecanoate. As auxiliary elements, benzyl benzoate and purified castor oil are used. The drug goes on sale in ampoules made of amber glass, which are placed in cardboard boxes with a glued ampoule holder.

Pharmacology

How do testosterone receive undecanoate? Experts say that such an active form of the drug is formed by splitting the side chain.

Testosterone is called the male sex hormone, which has the entire spectrum of biological activity, which is necessary for the formation and maintenance of androgenic functions.

Synthesis of this substance occurs in the testicles, as well as in the adrenal cortex. During fetal development, as well as in early childhood and during puberty, this element contributes to the formation of male characteristics and sexual organs. Subsequently, this hormone provides support for androgen dependent functions and the male phenotype.

Insufficient secretion of this substance leads to the development of hypogonadism. Its symptoms include erectile dysfunction, depressed moods, decreased sexual desire, increased fatigue, regression, lack or underdevelopment of secondary sexual characteristics.

Also, such representatives of the stronger sex increase the risk of developing osteoporosis.

Properties

Testosterone undecanoate is prescribed to increase the inadequate level of endogenous testosterone, as well as reduce the signs of hypogonadism.

The nature of the action of this drug is due to the following properties:

• Androgenic (affects the epididymis, seminal vesicles, prostate gland);
• Protein-anabolic (affects the bones, muscles, kidneys, hematopoietic system, liver).

In men who suffer from hypogonadism, testosterone undecanoate reduces the mass of adipose tissue and increases lean body mass. It also prevents loss and promotes the growth of bone tissue, improves sexual function and has a positive psychotropic effect.

Indications for use

What is the purpose of using testosterone preparations undecanoate? The instruction says that for the representatives of the stronger sex, such remedies are used as hormone replacement therapy for violations due to secondary or primary testosterone deficiency, including post-stroke syndrome, hypopituitarism, eunuchoidism, endocrine impotence and certain infertility caused by impaired spermatogenesis, as well as menopausal Disorders in men (for example, with a decrease in physical and mental activity, libido).

In transsexuals with a change of sex (for men), this medication is prescribed for masculinization.

Also testosterone undecanoate can be used in osteoporosis, which is caused by androgen deficiency.

Contraindications

Testosterone undecanoate (ampoules and tablets) is not allowed for use with:

• Androgen-dependent carcinoma of the prostate;
• Hypercalcemia, which is accompanied by malignant tumors;
• Androgen - dependent carcinoma of the mammary gland in representatives of the stronger sex;
• Hypersensitivity to the main substance or any auxiliary component of the drug;
• A liver tumor in the anamnesis or at present.

It should also be noted that testosterone undecanoate ("Nebido") is not prescribed to women.

With special caution it is recommended for patients with the syndrome of apnea and children in adolescence.

Method of use of tablets

Tablets that increase testosterone in men, should be taken only in the process of eating food. In this case, the food should not contain too much fat. Otherwise, the absorption of the drug through the lymphatic system will be maximum.

When taking tablets on an empty stomach, their absorption is minimal.

If the drug was prescribed to increase testosterone in the stronger sex, it is prescribed twice a day.

To increase the level of androgens, the medication is taken in a dosage equal to 120-160 mg, every day for 3 weeks.

For severe anabolic effects, experts recommend using high doses of medication. In this case, it is necessary to take 240 mg of the drug every day. It should be borne in mind that such a dosage can lead to the development of adverse reactions.

Use of the injection form of the drug

The introduction of the drug "Nebido" in a dose of 1 g of testosterone undecanoate (ie 1 ampoule) is carried out once a day for 10-15 weeks. Such frequency of injections provides support of a sufficient level of a hormone that does not cause its cumulation.

The drug is administered intramuscularly immediately after opening the ampoule. Injection is done slowly. In this case, ensure that the drug does not enter the blood vessel.

Before you begin treatment, you should consult a doctor. The latter is required to determine the amount of testosterone in the serum.

The interval between the first injections should be at least 6 weeks.

At the end of this interval, the concentration of testosterone in the blood should be checked. If its level is below normal, then the interval between injections is to be reduced.

If the concentration of testosterone is high, then it is necessary to consider increasing the interval.

Side effects

After taking the tablets in the strong can develop the following undesirable effects:

• Frequent erections, active sexual development, an increase in the sexual organs of adolescents;
• Retention of sodium and water;
• Increased libido;
• Oligospermia;
• Priapism and other signs of sexual stimulation;
• Nausea and dizziness.

When intramuscular injection of the drug in men observed:

• Increased hemoglobin, hypersensitivity;
• Weight gain, hypercholesterolemia;
• Increased appetite, polycythemia;
• Increase in the number of erythrocytes, depression;
• Insomnia, migraine, anxiety;
• Aggression, headache, irritability;
• Hot flashes, dizziness, hypertension;
• Bronchitis, dyspnea, sinusitis, diarrhea;
• Rash, arthralgia, papular rash, pain in the limbs;
• Itching, muscle tension, dry skin, etc.

Price and analogy

Testosterone undecanoate in the pharmacy can be purchased for 1000-1200 rubles.

Analogues of this medication are such drugs as Andriol, Androxon and Virigen. To determine which of the listed drugs should be used in the therapy process, only an experienced specialist will be able to use the data of the medical examination and analyzes.

Reviews of men about the drug

Testosterone undecanoate is a drug that is often used as hormone replacement therapy. Most men who take this medication, speak of it exclusively on the positive side. According to their reports, testosterone in tablets is less effective than a similar drug, but in an injectable form. Therefore, many patients try to purchase the drug in ampoules.

Although there are also men who claim that the testosterone undecanoate tablets are just as effective as injections. Moreover, they are much more convenient, because you can take them not only at home, but also at work, rest and so on.