Means "Etaperazin". Instructions for use

The medicine "Etaperazin", whose price is 250 rubles, is a neuroleptic (antipsychotic), piperazine derivative of phenothiazine. Presumably, the effect of the drug is due to the blocking in the mesolimbic brain structures of dopamine postsynaptic receptors. The drug has a strong antiemetic effect - the central mechanism manifests itself in the inhibition or blockade of D2-dopamine receptors by the triggered homoreceptor cerebellar zone, and the peripheral mechanism is in blockade in the gastrointestinal tract of the vagus nerve. The drug is different and alpha-adrenoblocking effect. Sedation and anticholinergic effects may be weak or moderate intensity, hypotensive activity is poorly expressed. The medicine "Etaperazin" (reviews of experts confirm this) also has a relaxing effect on the muscles. Antiemetic effect may be enhanced by sedatives and anticholinergics. Drug withdrawal occurs mainly with urine.

Appointment

"Etaperazine" is recommended for the treatment of mental disorders, accompanied by excitation and hyperactivity. The indications include schizophrenia, neuroses complicated by stress, fear. The drug is indicated with skin itching, to eliminate vomiting or nausea of a different nature of occurrence.

The medicine "Etaperazin".
Instructions for use

The recommended dose for patients with 12 years is 4-80 mg. On the basis of chronic course of pathologies, the amount of medication is allowed (on the recommendation of a specialist) to increase to 150-400 mg. Duration of admission and its frequency per day is determined exclusively by the doctor.

Side effects

"Etaperazin" (instructions for use warns about this) can provoke extrapyramidal reactions of the parkinsonian and dystonic type, melanosis, cholestatic jaundice, blurred vision, photosensitization. The undesirable consequences include akathisia, a skin rash accompanied by dermatitis, drowsiness, difficulty with urination. On the basis of the treatment is probably a disruption of accommodation, dry mouth. Seldom there is a heat stroke, agranulocytosis.

Contraindications

Means "Etaperazin" instruction for use does not allow for administration in hepatitis, cirrhosis, hematopoiesis, nephritis, hemolytic jaundice, during lactation. Contraindications include pathology of the spinal cord and brain of the systemic type in the progressing course, pregnancy, bronchoectatic disease in the late stage, hypersensitivity. The drug is not recommended for thromboembolic diseases, heart failure of decompensated type. Caution when prescribing the medicine "Etaperazin" (instructions for use contains such data) show with Parkinson's disease, alcohol intoxication, disorders of the liver. Dose adjustment may be required if there is a predisposition to the occurrence of glaucoma, epileptic seizures, pathologies of the chronic respiratory system. Carefully apply this medication in the treatment of weak, depleted patients, elderly patients and children.