"Dirofen" (suspension): anthelmintic preparation for animals

What is a veterinary drug like "Dirofen" (suspension)? Instructions for using this medication will be described in detail in this article. Also you will learn about the indications for its use, side effects and pharmacological features.

Composition of the medicine, its packaging

"Dirofen" is an anthelmintic suspension intended for oral use. Its international nonproprietary name sounds like "pirantela pamoat and prazikvantel". It is these components that veterinary medicine contains as its main ingredients. It also includes pumpkin oil.

"Dirofen" is a suspension packed in 10 ml vials of polymer, which together with stickers for the veterinary passport and a syringe-dispenser are packed in cardboard packs.

Properties of the medicinal product

"Dirofen" is a suspension for kittens and other animals, which is a combined agent that has a wide range of activities with regard to tape and round helminths.

The prasiquantel, which is part of this medication, is able to increase the permeability of cell membranes for Ca ions, and also inhibit the enzyme of the parasite, fumarate reductase, thereby causing a spasmodic contraction of the muscles that passes into paralysis.

Mechanism of action

What determines the effectiveness of the drug "Dirofen"? Suspension, including a substance such as pyrantelum pamoate, is capable of blocking neuromuscular transmission, as well as impairing the permeability of cell membranes and inhibiting cholinesterase. Ultimately, this effect of the drug leads to death and paralysis of helminths.

Kinetic features

"Dirofen" is a suspension for oral administration. After entering the animal's body prazikvantel is quickly absorbed from the gastrointestinal tract and reaches a peak in its concentration in the blood after 3 hours.

The substance in question is well distributed in tissues and organs, after which it is excreted from the body in the form of derivatives along with urine (within 24 hours).

As for pyrantel pamoate, this component is rather poorly absorbed from the gastrointestinal tract, providing a prolonged parasiticidal action in the intestine. The excretion of this substance from the animal's body takes place unchanged with the feces.

Features and properties of the additional component

What role does pumpkin oil play in the drug "Dirofen"? Suspension, the reviews of which are presented further, thanks to this component, has a unique chemical composition. It includes carotenoids, a complex of vitamins (PP, group B and C), as well as polyunsaturated fatty acids and microelements.

One can not help saying that pumpkin oil can stimulate local immunity, accelerate the regeneration of intestinal cells damaged by parasites, enhance peristaltic contractions of this organ, and facilitate and accelerate the process of releasing the body from helminths.

"Dirofen" is a suspension for puppies and other animals that belongs to moderately dangerous drugs. In recommended dosages, it does not have embryotoxic, local irritating, teratogenic and sensitizing effects.

Indications for the use of a veterinary drug

Why is this drug prescribed to animals? Experts argue that such a medicine is an excellent preventive and therapeutic agent that is actively used in the diagnosis of cestodias and nematodoses in puppies and kittens, as well as in mixed invasions in other animals.

Only an experienced veterinarian should prescribe this medication.

Prohibitions on the use of veterinary drugs

To treat animals with the anthelmintic remedy "Dirofen" is allowed only on strict indications and in recommended dosages. It should be borne in mind that this medication is prohibited to be used at high individual sensitivity of the animal to its main and auxiliary components.

It should also be noted that it is highly discouraged to de-worm kittens and puppies under the age of three weeks. The same applies to depleted and convalescent animals and pets suffering from infectious diseases.

It is strictly forbidden to prescribe a suspension of "Dirofen" together with piperazine derivatives and other drugs that inhibit cholinesterase.

Method of application of the veterinary product and its dosage

How should I give the drug "Dirofen"? The suspension being considered is administered to puppies and kittens orally once during morning feeding hours together with a small amount of feed.

If the animal refuses to use such food, then this medication is administered forcibly. Do this with a syringe dispenser (apply to the root of the tongue at the rate of 1 ml of suspension per 1 kg of body weight).

Before treating the animals with the anthelmintic preparation "Dirofen", the vial of the drug substance should be shaken vigorously (for 2 minutes).

Preliminary application of laxatives or a starvation diet with the use of this medication is not required.

With regard to prevention, in this case, deworming is carried out once in 95 days and before each vaccination.

Therapeutic measures aimed at the destruction of cestodes and nematodes are carried out only after the indications, after consultation with the veterinarian.

In severe invasion, the suspension is administered again after 10 days.

Actions of a negative nature

As mentioned above, "Dirofen" is a moderately dangerous drug. In very rare cases with overdose and the presence of high individual sensitivity in animals can occur: depression, vomiting, increased salivation, disturbances in the functioning of the digestive system and various allergic reactions. Also, puppies can refuse to eat food.

Reviews of the owners of animals

Helminthiasis is a fairly common disease that occurs in animals. To treat it should be necessary, otherwise it will lead to a painful condition of the puppies and a lethal outcome.

According to the responses of the owners of animals, "Dirofen" is an effective anthelminthic agent, which does not cause adverse reactions. Its use makes it possible to cure diseases such as cestodiasis and nematodosis in a short time.

Consumers claim that the use of this medication is not particularly difficult. It is simply mixed with food and given to animals in the morning feeding hours.