Health, Preparations

Piperazine. Reviews, instructions

Anthelminthic drugs are called drugs that are designed to remove helminth from the human body. Depending on the class of helminths, such medicines are divided into three groups. They have a detrimental effect on the ascarids, pinworms and so on.

The most effective anthelminthic drug is the drug "Piperazin." The price, feedback and method of its application are presented below.

Composition, shape, packing

What form is inherent in such a drug as Piperazine? Patients' feedback reports that this drug can be purchased in the form of tablets that are contained in contour cells. Their main component is piperazine adipate. In addition to it, the composition of the drug includes such additional compounds as calcium stearate and starch.

Pharmacodynamics of the drug

What features are characteristic for such a drug as "Piperazin"? Instructions for use, expert reviews argue that this anthelminthic agent is intended for the treatment of ascaridosis and enterobiosis.

This drug adversely affects the individuals of pinworms and ascaris of all sexes, both immature and sexually mature. It paralyzes the muscles of nematodes and disrupts the work of the system of their neuromuscular transmission.

With a single tablet administration, the efficiency of de-worming is about 93-95%. When the remedy is used again, this value reaches 100%.

In view of the fact that this medicine is not capable of affecting the shell of ascaris, but only causes paralysis of their muscle tissues, there is no possibility of absorption of toxic products of worm decay.

One can not help saying that this medication is ineffective when infecting other nematodes, as well as in cestodiasis and trematodes.

Kinetic properties

Is the anthelminthic drug "Piperazine" absorbed? Reviews say that this remedy is absorbed very quickly from the intestine. It is isolated from the human body through the kidneys.

Indications

In what cases is the most effective active substance of the drug, such as piperazine adipate? Experts say that this medicine is intended for treatment:

Enterobiosis;
Ascaridosis.

Contraindications

In what cases should not take such a substance as piperazine adipate? Reviews say that it is contraindicated in the presence of the patient's allergic reactions. Also, the drug should not be used in nephritis, epilepsy, organic lesions of the central nervous system, kidney or liver failure of a chronic nature.

Method of administration and dosage

The drug "Piperazine" for children (reviews on tablets will be presented below) can be prescribed. However, this medicine should be taken only with strict indications.

According to the instructions, with ascariasis and enterobiosis, this medication is consumed twice a day, for two consecutive days (although there may be other schemes). Do this one hour before a meal or 60 minutes after it.

Single dose for children under one year is 200 mg, for babies 2-3 years - 300 mg, 4-5 years - 500 mg, 6-8 years - 750 mg, 9-12 years - 1 g, and 13-15 years - 1.5 g.

For adults and adolescents from 15 years, the dose of the drug should be 1.5-2 g.

The course of treatment of this drug, as a rule, should last for five days. According to experts, this medication is taken in cycles (three) at intervals of seven days.

Between the courses you need to do enema (at night) with sodium bicarbonate and water (for 250 ml of water ½ dessert spoon of soda).

For babies, the volume of enema includes up to 3 glasses of liquid, and for adults - up to 5.

It should also be noted that the drug in question is often used to treat agricultural and domestic animals. According to the instruction, for them the medication is indicated for toxaxaridosis, uncinoria, ankylostomosis and trichocephalosis.

Adverse events

Anti-wrinkle tablets "Piperazin", reviews of which are ambiguous, can cause such adverse reactions as:

Hallucinations, ataxia, vision impairment, dizziness, nystagmus, headache, paresthesia, vomiting, chorea, euphoria, impaired coordination, tremor;
Skin rashes, including erythema polyforma, urticaria, purpura, as well as bronchospasm, Stephen-Johnson syndrome, itching, arthralgia, fever;
Nausea, drowsiness, areflexia, weakness, spastic epigastric pain, diarrhea, convulsions.

The risk of such effects, including neurotoxic effects, is much higher in people suffering from kidney failure.

Special Recommendations

Therapy with this drug does not require a specialized diet, as well as any other training of a person. When prone to constipation, the patient is prescribed laxatives.

In the treatment of enterobiasis , strict hygiene should be observed in order to improve the results of therapy.

Carry out treatment with this drug is acceptable in outpatient settings.

Weakened people with anemia require careful medication.