"Artra MSM Forte": instructions and references

What can replace such a tool as "Artra MSM Forte"? Analogs of this drug will be listed at the end of the article. Also you will learn about the form in which this medicine is produced, what users are saying about it, and how to use it correctly if there are indications for use.

Form of release of the drug, its composition, description and packaging

"Artra MSM Forte" - pills biconvex, oval, covered with a film membrane. They can have a light yellow-orange or dark orange color, as well as a specific smell.

The main ingredients of this drug are such elements as chondroitin sodium sulfate, methylsulfonyl methane, glucosamine hydrochloride and sodium hyaluronate in the form of hyaluronic acid.

As for additional components, they include microcrystalline cellulose, croscarmellose sodium, calcium dihydrate hydrophosphate, stearic acid, colloidal silicon dioxide and magnesium stearate.

The film membrane of the drug in question includes: orange opadrai II, talc, triglycerides, maltodextrin, dye yellow sunset.

The tablets "Artra MSM Forte" are sold in white bottles with a screw cap made of dense polyethylene.

Pharmacodynamic characteristics

What is Artra MSM Forte? Experts say that this medication is a stimulant of restorative processes in cartilage tissues. The active ingredients of this preparation take part in the synthesis of connective tissues, as well as prevent the destruction of cartilage and stimulate the regeneration of its tissues.

The use of exogenous glucosamine significantly enhances the production of cartilage matrix and protects (nonspecifically) the cartilage from possible chemical damage.

Features of the tool

What are notable tablets "Artra MSM Forte"? The instruction says that the glucosamine contained in this drug in the form of a sulfate salt is a kind of precursor of hexosamine. As for the anion sulphate, this substance is necessary for the production of mucopolysaccharides of connective tissue.

One can not help saying that glucosamine has another supposed function. This is the protection of already damaged cartilage tissues from their further destruction, which was caused by the use of GCS or NSAIDs.

What role does chondroitin play in the preparation "Artra MSM Forte"? According to the instruction, this component performs the work of an additional substrate, which promotes the formation of a healthy matrix of cartilage.

It should also be noted that chondroitin:

• Stimulates the mechanisms of repair of cartilaginous tissues;
• Stimulates the synthesis of type II collagen, hyaluronan and proteoglycans;
• Inhibits the action of enzymes that break cartilage (elastase and hyaluronidase);
• Suppresses the activity of free radicals, and also protects hyaluronan from cleavage, which is caused by enzymes and the aggressive action of free radicals;
• Maintains the proper viscosity of the synovium.

In addition, in people suffering from osteoarthritis, this substance eliminates the symptoms of the disease and reduces the need for NSAIDs.

Kinetic capacity

How are active substances "Artra MSM Forte 60" absorbed? The biological availability of glucosamine for oral administration is 25%. In the human body, in the highest concentration, this substance is found in the kidneys, cartilage of the joints and liver.

About 1/3 of the dose taken for a very long time remains in the bone tissue and muscles. In this case, most of the substance of this element is excreted by the kidneys in unchanged form, and the remainder - together with feces. The half-elimination time of glucosamine is 68 hours.

After oral administration of 800 mg of chondroitin sulfate, its plasma concentration increases dramatically throughout the day. At the same time, the absolute bioavailability index is 12%.

About 1/10 of the dose is absorbed in the form of high molecular weight derivatives, and approximately 20% in the form of low molecular weight metabolites.

This component is metabolized by desulfurization. From the patient's body it is excreted by the kidneys. Its half-elimination time is approximately 5 hours.

Indications for prescription of tablets

At what diseases is the most effective medicine "Artra MSM Forte"? The responses of sick people report that this drug is good for:

• Osteochondrosis of the spine;
• Osteoarthritis of peripheral joints.

Prohibitions to prescribe medication

What are the contraindications to the use of tablets "Artra MSM Forte"? Experts argue that this medication is not recommended for use with:

• The bearing of the fetus, that is, during pregnancy;
• During the period of breastfeeding;
• In children under the age of 15;
• High sensitivity to drug substances.

Also, with caution, this remedy is used when there is a violation of blood coagulability, diabetes mellitus, bronchial asthma and intolerance to various seafood (including shrimp, shellfish).

The preparation "Artra MSM Forte": instructions for use

In what dosage should I take the medication in question? The attached instructions say that in the first three weeks of therapy, tablets should be consumed twice a day (one piece each). In the following weeks and months, the frequency of application is reduced to once a day.

This drug is intended for therapy of people over 15 years of age. It should be noted that the therapeutic effect and absorption of active substances of this drug does not depend on the time of day, nor on food intake.

To achieve a sustainable treatment result, at least six months of therapy is required.

As a supplement to the main treatment to improve the functional state of the musculoskeletal system, patients can be recommended capsules "Artro-Active". The daily dosage of such dietary supplements is 4-6 capsules.

The treatment under consideration is carried out by courses lasting from two weeks to a month. The optimal time between courses is 14 days.

Actions of a negative nature

What side effects occur after taking the "Artra MSM Forte" tablets? According to experts, against the background of the use of glucosamine, such digestive disorders as bloating or flatulence, constipation, epigastric pain and diarrhea are very often recorded. The following negative reactions are also possible:

• Headaches;
• dizziness;
• Peripheral edema;
• Drowsiness or, on the contrary, insomnia;
• Cutaneous manifestations of allergy;
• Pain in the legs;
• Tachycardia.

One can not help saying that taking chondroitin often provokes the development of hypersensitivity reactions.

Cases of overdose and interaction with other medicines

About cases of overdose with tablets "Artra MSM Forte" for today nothing is known. However, experts argue that when taking a large number of tablets (more than 10 pieces), the patient may experience nausea, diarrhea, hemorrhagic eruptions and vomiting. Treatment of such a condition is symptomatic (that is, gastric lavage is required).

How does "Artra MSM Forte" interact with other medicines? This agent increases the absorption of tetracyclines, and also reduces the effect of semisynthetic penicillins. One can not help saying that this medication is compatible with NSAIDs and SCS. At the same time, against the background of its use, it is possible to increase the effect of antiplatelet agents, indirect anticoagulants and fibrinolytics.

Special Information

When developing adverse reactions from the digestive tract, it is recommended to reduce the dosage prescribed by the doctor to a minimum. If after this improvement does not occur, then you need to stop taking the medication.

It is highly undesirable to give "Artra MSM Forte" tablets to children under 15 due to the lack of any scientific data for this category of people.

The considered preparation does not render any influence on process of driving of the car, and also management of other dangerous mechanisms.

Similar drugs and the cost of medicine

How much does the medicine that we are considering cost? Its price in the Russian Federation is approximately 750 rubles for 30 tablets.

If the effectiveness of this drug does not suit you, then it can be replaced by one of the following analogs: KONDRONOV, Teraflex, Tazan, Hondroflex, Adgelon, Chondroglucid, Alflutop, Gamma-Planet , "Biartrin", "Diskus Compositum", "Traumel S", "Synovial", "Rumalaya", "SinoArt", "Objective T", "Chondrotek Forte".

Reviews

The patient's comments about the drug in question are contradictory. Some patients claim that three months after the start of taking this medication they felt a significant improvement, and other people say that already in the first days of treatment they encountered the development of unpleasant side effects and did not see the results of therapy at all.

According to experts, the peculiarity of this medicine lies in the fact that it contains active substances, which are natural structural components of cartilaginous tissue and intra-articular fluid. Thus, the effect of the use of this drug is directly related to the replacement of the deficiency of these compounds in the human body. It should be noted that most doctors are not very satisfied with the results of using the drug in question. They argue that this medication can not be used as the main drug. It can be used only for auxiliary therapy, together with other more effective means.