Antihypertensive tablets "Equator"

Tablets "Equator" are a combined antihypertensive drug, the use of which helps reduce blood pressure, general vascular resistance and preload. The basis of this drug is a decrease in the concentration of aldosterone and angiotensin II in plasma, as well as an increase in the index of the bradykinin vasodilator. In addition, this combined agent prevents the entry of calcium ions into the smooth muscle cells of the vessels and myocardium due to the inhibition of the so-called calcium channels. Reducing afterload on the heart and the expansion of arterioles and arteries of the peripheral type similarly provides the drug "Equator". Tablets, the price of which is an average of 450 rubles, also have a pronounced antianginal effect.

As for the composition of this antihypertensive agent, as active (active) components it contains lisinopril and amlodipine besylate dihydrate. In the role of additional substances are sodium starch glycolate, magnesium stearate, microcrystalline cellulose 101 and 12.

The main indication for the appointment of a combination drug, such as the tablet "Equator", is essential hypertension. As a contraindication to the use are edema Quincke, angioedema edema diopatic or hereditary type, cardiogenic shock, myocardial infarction, an allergic reaction to amlodipine besilate or lisinopril dihydrate. In addition, do not use this antihypertensive agent for arterial hypotension, hemodynamically significant aortic stenosis or mitral valve, unstable angina, heart failure and hypertrophic cardiomyopathy. Tablets from the pressure "Equator" is not recommended for children of children, pregnant and breast-feeding mothers.

With great care this drug is used in azotemia, coronary heart disease, bradycardia, coronary insufficiency, tachycardia, cerebrovascular diseases, mitral stenosis, primary hyperaldosteronism, hyperkalemia, aortic stenosis, kidney and liver disorders, diabetes mellitus and lupus erythematosus.

Separately, it is worth mentioning the possible side reactions associated with the use of this combination drug. For example, tablets "Equator" can provoke headaches, weakness, drowsiness, dizziness, nausea, diarrhea, dry cough and vomiting. In addition, agranulocytosis, orthostatic hypotension, sleep disturbances, angioedema of the face, hyperkalemia, mood changes, bronchospasm, visual impairment, dyspnoea, rhinitis, gynecomastia, allergic alveolitis, tinnitus and nocturia can be observed. Arthralgia, skin rashes, itching, Reynaud phenomenon, tremor, myalgia, fatigue, paresthesia, asthenia, dyspepsia and hyperesthesia can also be provoked by therapy, the main place in which take the tablets "Equator".