The drug "Spitomin": reviews of doctors, instructions for use, composition and indications

"Spitomin" is an anxiolytic drug. It is a tranquilizer, which also has an antidepressant effect. The difference between this drug and other tranquilizers is that it does not have a muscle relaxant, hypnotic, sedative and antiepileptic properties.

Composition and form of the preparation "Spitomin"

The drug has in its composition active substance buspirone. "Spitomin" is produced in the form of tablets in which the dose of the active ingredient can be 5 mg and 10 mg. Of the excipients in the drug are anhydrous colloidal silicon dioxide, magnesium stearate. Auxiliary action has additional ingredients - carboxymethyl starch, microcrystalline cellulose and a substance such as lactose monohydrate.

pharmachologic effect

The drug "Spitomin" reviews doctors can be attributed to medicines nonbenzodiazepine series, its action is defined as antidepressant. The medicine has some differences from the classic variants of anxiolytics. The effect of the drug is related to the effect on the human body of buspirone. It affects the activity of dopaminergic and serotonergic systems. Buspirone, acting on the dopamine presynaptic receptors, blocks them, contributes to an increase in the rate of activation of dopamine neurons located in the middle brain.

The active component does not have a negative effect on the implementation of psychomotor functions, it does not lead to the development of tolerance. The use of "Spitomina" excludes the appearance of withdrawal syndrome and dependence on this drug. The use of the drug "Spitomin" instructions for use, reviews do not associate with the negative reflection on the action that has on the body ethanol. To obtain the necessary therapeutic effect, it is necessary to treat 1-2 weeks, the maximum possible effect can be seen only a month after the start of therapy.

Indications for the use of the drug "Spitomin"

The drug is prescribed in such cases:

• Panic disorder ;
• Alcohol withdrawal syndrome (used as part of complex treatment);
• A syndrome in which the autonomic function is disrupted;
• Anxiety disorder generalized;
• Depressive disorders (used as part of combination therapy as an adjuvant).

Contraindications to the reception of "Spitomin"

"Spitomin" instruction, reviews are not recommended when:

• Hypersensitivity to components;
• Myasthenia gravis;
• Glaucoma;
• Breast-feeding;
• Pregnancy and suspected of its presence;
• Severe liver and kidney failure;
• Children (less than 18 years);
• Admission of MAO inhibitors, a fourteen day period after the cancellation of the irreversible MAO inhibitor, and one day after the rejection of the MAO inhibitor is reversible.

In some cases, the drug should be used with caution:

• Kidney failure;
• Cirrhosis.

Regarding the reception during the period of carrying the child of the "Spytomin" remedy, the patients' feedback shows that such an opportunity exists. However, the doctor must be constantly monitored. Possible benefits for the woman's body should exceed the risk that exists for the fetus.

Drug administration, dosage

Tablets are drunk at the same time. It is possible to take the remedy both before eating and after, you should choose one option and always stick to it.

The drug is not suitable for occasional use in the occurrence of anxiety, because the therapeutic effect is detected not immediately, but after a while. It takes multiple uses of Spitomina.

The required dose is set for each patient separately. "Spitomin" customer reviews are presented as a drug, the dose of which at the initial stage of treatment in most cases does not exceed 15 mg of medication per day. A dose increase is possible every 2-3 days. In this case, its increase should be gradual, no more than 5 mg at a time. Daily use of the drug is recommended in 2-3 sessions. In general, the dosage of the drug per day is 20-30 mg. The maximum dose of the drug available for use at a time corresponds to 30 mg, the maximum possible daily intake is 60 mg.

Violations in the work of the kidneys require the implementation of therapy based on a reduced dose. When problems with the liver need special care during the treatment with "Spitomin", the dosage should also be reduced. To this end, the doctor usually reduces certain doses, while increasing the intervals between taking the remedy.

Side effects of Spitomina

"Spytomin" tip is not always positive, and this is due to its ability to cause some unwanted reactions of the body. Usually the drug is well tolerated by the patient's body, however, side effects can sometimes be detected. If they develop, it basically occurs at the very beginning of therapy, side effects disappear on their own. Reduction of the established dosage is rarely required.

A person can discover problems with sleep, a significant increase in nervous excitability, and a headache. In very rare cases, extrapyramidal disorder may occur . There may be changes in the digestive system, these are various dyspeptic phenomena, for example nausea with vomiting, poor appetite.

When an overdose of "Spitomin" drug reviews many experts confirm the need to perform gastric lavage and provide therapy aimed at eliminating this condition. There is no antidote, the effect of dialysis is absent.

special instructions

Insufficiency of the liver

Metabolism of the active substance occurs in the liver, with the introduction of 20 mg of the agent at one time to a patient with cirrhosis, the concentration of buspirone in the blood increases, the drug is removed from the body longer. Since the substance can get into the bile in unchanged form, a repeated peak of the level of the active ingredient in the blood is possible.

Insufficiency of the kidneys

Regarding the treatment with "Spytomin", the doctors' feedback shows if the insufficiency manifests itself moderately or heavily, the clearance of the active component may become half lower. Severe insufficiency, in which GFR does not exceed 10 ml / min, its moderate form at the rate of 10-30 ml / min and mild, when the index is more than 30 ml / min, are those conditions under which treatment with Spitomin is possible ", But in a reduced dose and with special care.

Lactose intolerance

Since the tablets contain lactose, this factor should be taken into account when appointing patients "Spitomina."

Influence on the rapidity of reactions and attention

Usually the drug does not exert such influence, however its presence should be determined individually.

Transition from benzodiazepines

The use of the drug is possible only after the withdrawal of benzodiazepines by gradually reducing the dosage.

Predisposition to drug dependence

After treatment with "Spytomin", the patients' review confirms the absence of addiction to the medication. But if a patient has a predisposition to depend on drugs, he needs careful monitoring of a specialist.

Advice to patients

Do not drink alcohol and grapefruit. It is forbidden to drink juice from grapefruit in large quantities. These products help increase the concentration of active substance in the blood. In addition, they increase the likelihood of side effects and the severity of their course, the frequency of manifestation.

Drug Interactions of Spitomina

The drug can not be combined with MAO inhibitors. Its use during the period of taking antidepressants, oral contraceptives, antipsychotics should be done with caution. The same applies to cardiac glycosides and hypoglycemic drugs, hypotensive.

The cost of the drug "Spitomin"

When treatment with Spytomin, the instructions for use, price, reviews are important information for patients. The drug with a dose of active substance 5 mg (60 pcs.) Can be purchased for about 725 rubles., Tablets with 10 mg of the active ingredient (60 pcs.) - for 750-1200 rubles.

Reviews, analogues of the drug "Spitomin"

The drug "Spytomin" price, reviews make a beneficial and effective tool in the treatment of conditions indicated in the indications of the instruction. The patient's opinion about the drug contains some unpleasant moments. For example, a drug when combined with "Fenlepsin" can lead to a deterioration of well-being, which can manifest as a faint, dizziness, but such side effects disappear with time. When treating "Spitomin" anxiety states, there may be a headache, nausea, but later they also pass, the result of therapy becomes noticeable. Unwanted reactions of the body to "Spitomin" are rare cases.

Doctors confirm the effectiveness of the drug when used in order to combat some pathological conditions of the body. In their opinion, with the proper use of Spitomin, recovery always comes.

The only analogue of the drug is Buspiron Sandoz, this option is cheaper. The specialist can choose a substitute for the drug without the presence of buspirone in the composition, usually these are tranquilizers that make up the benzodiazepine series. Such tasks are carried out on an individual basis, taking into account the disease and its severity, the general state of health.