The drug "Grippostad": instructions for use, analogues and reviews

Autumn and spring are characterized by an increase in the number of acute respiratory diseases. During the off-season in all drug stores in the world, cold and flu medicines are best sellers. Among other drugs that fight with acute respiratory diseases, one of the first places is a series of medicines Stada company under the trademark "Grippostad". These medicines have shown themselves well in the treatment of colds and are very popular all over the world.

Dosage forms

Preparations under the trademark "Grippostad" are produced in the following dosage forms:

• Powder from which the drink is prepared for ingestion.

• "Gripostad Reno" - nasal drops for children (0.05%) and adults (0.1%).

• Grippostad Reno (0.1%) is a nasal spray.

• Grippostad C - capsules.

• Grippostad herbal - syrup.

All these medicines have different composition, application features, contraindications and side effects. Let us consider each of them in detail.

Powder

This drug is very popular. "Grippostad" is a powder, the instruction for use of which is necessarily present in each package, containing the main active ingredient paracetamol in a dosage of 600 mg. Also in its composition there are additional components: ethylcellulose, silicon dioxide, vitamin C, aspartame, citric acid, sucrose and citrus flavor.

How does the drug work?

"Grippostad" - a powder (the instruction on which application advises to dissolve it in hot water) - refers to preparations of the genus of analgesics and antipyretics. Its main active ingredient paracetamol is absorbed through the walls of the stomach and intestines and reaches its maximum concentration in the blood plasma 30-60 minutes after administration. It spreads to all organs and tissues and is metabolized by the liver. This drug is excreted by the kidneys for two hours. The duration of the drug is 4-6 hours. In people with impaired renal function and elderly patients, excretion of paracetamol is slow. In connection with this fact, the drug should be approved with a doctor.

An important component of this product is ascorbic acid, or vitamin C. This biologically active substance is an important link in the oxidation and reduction processes of the human body, regulates carbohydrate metabolism, blood coagulability, promotes tissue regeneration, participates in the immune system, reduces vascular permeability, reduces the need In some vitamins and slows the excretion of paracetamol, alleviating its toxicity.

Indications and contraindications

The powder "Grippostad", the instruction to which describes its properties, is an analgetic and antipyretic agent and has a slight anti-inflammatory effect. Based on this, it is shown under the following conditions:

• fever syndrome, which accompanies colds and flu;

• Pain of moderate and weak character, including neuralgia, myalgia, menstruation;

• trauma, burns;

• headache and toothache.

The drug has its own contraindications. Powder means "Grippostad", the instruction to which warns about possible side effects, should not be taken with the following diseases:

• kidney failure;

• high blood pressure;

• gastric bleeding;

• deficiency of the enzyme glucose-6-phosphate dehydrogenase.

Also, this drug is contraindicated in pregnancy, lactation and children under 6 years of age.

With increased caution, you should use "Grippostad" in the form of powder to people with erosions and gastrointestinal ulcers, especially during an exacerbation, as well as chronic alcoholism and liver diseases.

Admission of this drug should be selected in accordance with age and weight. Adult patients "Grippostad" in the form of powder is taken 3-4 times a day for 2 packets, but not more than 6 per day. For children, the dosage is determined according to the weight. These recommendations are very important to consider when treating.

In case of overdose, the following conditions are observed:

• nausea, vomiting;

• weakness;

• necrosis of liver cells.

In order to eliminate the toxic effect, the patient is administered a preparation of methionine and acetylcysteine, controlling the concentration of paracetamol in the blood. Therapy is continued until stable indicators are achieved.

Is it compatible with other drugs?

Not all drugs can be taken "Grippostad" (the instruction for this warns). Therefore, it is very important to consider the following instructions:

• When combined with substances that enhance microsomal oxidation of liver cells, there may be a risk of severe intoxication even with a slight drug overdose. These substances include ethanol, barbiturates, fetoin, rimfapicin, phenylbutazone, antidepressants of the tricyclic type.

• Joint intake with substances that inhibit microsomal oxidation reduces the thermal action of paracetamol on the liver.

• When using ethanol during the treatment period, "Grippostad" has a serious risk of developing pancreatitis in an acute form.

• Joint reception with uricosuretics reduces the effectiveness of the latter.

• With simultaneous reception with propanthelin, the speed of the evacuation capacity of the stomach decreases, "Grippostad" is absorbed more slowly. The drug "Metaklopramedin", on the contrary, enhances the patency of the food lump, and the action of paracetamol is accelerated.

• Joint administration with chloramphenicol increases the toxic effect of the latter.

• When used with coagulants of indirect type, their activity is intensified.

Side effects of the drug and its reception

There may also be side effects from taking the powdered drug Grippostad. Instructions for use indicate the following reactions:

• Allergic manifestations: itching, rashes on the skin, angioedema and urticaria.

• Disturbances in the hemopoietic system: thrombocytopenia, anemia, agranulocytosis. In the case of long-term use in high concentrations, a violation of hematopoiesis can develop.

• Violation of the digestive process, pain in the epigastric region, with prolonged intake of the drug may develop toxic damage to the liver.

• Neurotoxic reaction.

There are special instructions for taking the drug: it is impossible to use Grippostad, the instruction confirms this, for the removal of heat for more than 3 days in a row, and as an anesthetic for more than 5 days without a doctor's supervision.

The vitamin C in the composition has the property to distort the glucose and uric acid in the blood.

It is prohibited in parallel with the "Grippostad" to use other drugs with paracetamol, NSAIDs, other analgesics, antipyretic drugs, barbiturates, "Rifampicin", anti-epilepsy, "Chloramphenicol" without the permission of a doctor.

If the patient has diabetes mellitus, then he must take into account that the "Grippostad", the instruction for use of which must be read before the reception, contains 3.8 g of sucrose in one package.

If the patient suffers from alcoholism, the dosage of paracetamol is prescribed to him by the doctor individually to avoid toxic effects on the liver and its destruction.

"Grippostad Reno": drops and spray for the nose

This agent is a vasoconstrictor used in ENT-practice. "Grippostad Rino", the instruction on which application is obligatory for reading, is issued in the following forms:

• Nasal drops for children 0.05%.

• Solution-drops 0.1%.

• Nasal spray 0,1%.

The main active ingredient is xylometazoline hydrochloride at a concentration of 500 mg in children's drops and 1000 mg in solution and a spray. Additional components: benzalkonium chloride, monohydrate of citric acid, glycerol, sodium citrate dihydrate, purified water.

The drug "Grippostad Reno", the instruction to which is attached, produces a vasoconstrictor effect with topical application. Also, the edema of the nasal mucosa decreases markedly, the mucus branch becomes easier. Relief of the patient comes about 10-15 minutes after taking the drug.

"Grippostad" is a drop in the nose, the instruction to which indicates that it can be used at the following indications:

• Allergic rhinitis.

• ARI accompanied by rhinitis.

• Pollinosis.

• Average otitis media.

• Preparatory measures before examining the patient by an ENT doctor.

"Grippostad" is a spray (the instruction to it confirms its similarity in composition with drops), which is also used for the above symptoms.

This drug has contraindications for admission:

• High blood pressure.

• Tachycardia.

• Glaucoma.

• Atherosclerosis.

• Thyrotoxicosis.

• Atrophic rhinitis.

• States after surgery for the membranes of the brain.

• Intolerance to drug components.

With caution should be used in diabetes, stenocardia, pheochromocytosis, prostate cancer, pregnancy, lactation and in children under 2 years (drops) and up to 6 years (spray).

How correctly to accept?

What does the Grippostad package contain? Instructions, drops or spray (depending on the form of release) - all this is necessarily present in the box with the medicine.

The use of Gripostad Uno should not be continued for more than a week without a doctor's recommendation. If the nose formed crusts, then it is necessary to replace the product with a special gel.

The spray is injected into each nostril once, no more than four times a day. It is important not to overdose. Drops are instilled in 2-3 nasal passages.

There are also side effects from the nasal use of the drug "Grippostad". Instructions for use describe their symptoms in detail:

• Irritation of the nasal mucosa, burning, drying.

• Increased separation of mucus.

• Depressive state (prolonged use of high doses).

• Rarely: mucosal edema, tachycardia and arrhythmia, hypertension, migraine, vomiting, impaired vision and loss of sleep.

"Grippostad": capsules. Instructions for use

This drug is also called a tablet. It contains the following substances:

• Paracetamol DS in the amount of 208 mg.

• Ascorbic acid (vitamin C) - 160 mg.

• Caffeine in the amount of 25 mg.

• Chlorphenamineamineate 2.5 mg.

Based on the name of components of capsules "Grippostad C", it can be concluded that this drug is an analgesic and an antipyretic, that is, it helps a person cope with pain and heat.

The effect on the body of paracetamol and ascorbic acid was described earlier when we considered a powder analogue. In addition to these two components, Grippostad S contains:

• Caffeine is a xanthine derivative. Its feature is that it enhances the analgesic effect of paracetamol.

• Chlorphenamine maleate serves as an antihistamine and prevents increased permeability and reduced muscle (including bronchial). Also, it removes the swelling of the nasal mucosa, promotes the resumption of normal nasal breathing.

Side effects

What are the symptoms of capsules "Grippostad"? The instruction for the use of this medication tells us that this medication is prescribed for fever accompanying infectious and inflammatory diseases. Along the way, this medicine will help to cope with headache, arthralgia, myalgia, blockade of the nose and dry type cough.

What is in the capsule packaging "Grippostad"? Instruction, tablets. Guidelines for use must be read before taking the medication. It is important to know the dosage and not to break it in order to avoid serious consequences for the body.

Take capsules is allowed from the age of 12 to 2 pieces 3-4 times during the day, but not more than 12 tablets. To drink them follows a sufficient amount of still water. Long-term administration or modification of the dosage of "Grippostad C" is carried out only at the direction of the attending physician.

Side effects of the drug are related to the content of paracetamol and were listed in the description of the powder analogue of this drug.

"Grippostad C" is contraindicated under the following conditions:

• Severe kidney and liver disease.

• The reaction of the body to the components of the drug.

• Lack of enzyme: lactase.

• Children under 12 years.

• Period of pregnancy and lactation.

Before applying this medication, it is necessary to pay attention to the following special instructions. "Grippostad C" in the form of capsules should be treated with increased caution and only on the advice of a specialist if the patient has the following diseases:

• Liver and kidney pathologies.

• Diseases associated with the accumulation of iron.

• Alcoholism in chronic form.

• Gastric ulcer.

• Heart arythmy.

• Closed-angle glaucoma.

• Alarm status.

Paracetamol overdose, its symptoms and methods of elimination have been described above.

Cough syrup "Grippostad Grassy"

This remedy is effective in eliminating the symptoms of cough and colds, has an expectorant effect.

"Grippostad" is a cough syrup (the instruction for use is attached to the bottle), which contains, as the main active substance, dry extract of ivy (0.050 g).

Also in the composition there are the following auxiliary components: a solution of maltitol, bitter fennel oil, potassium sorbate, liquid licorice root extract, citric acid monohydrate, purified water.

How does the medicine work?

The drug has an expectorant and mucolytic effect, relieves spasm and facilitates the separation of sputum. "Grippostad Grassy" is indicated for diseases of the human respiratory system in acute and chronic form (bronchitis, tracheobronchitis, pneumonia).

The syrup is applied inside without dilution with water or in a diluted form. A syrup can be drunk with the necessary amount of liquid. Dosage depends on age:

• Children 1-5 years - 2.5 ml three times a day.

• Children 5-12 years - 2.5 ml four times.

• Children from 12 years and adults - 5 ml three times a day.

When taking Grippostad Herbal, a side effect may appear. It can be as follows:

• Digestive disorders: vomiting, diarrhea.

• Very rarely: allergies in the form of dyspnea, exanthema, angioedema and urticaria.

The drug should not be taken if there is a reaction to the components of the drug, pregnancy and lactation, intolerance to fructose.

"Grippostad Grassy" contains maltitol, which should be taken into account in patients with diabetes mellitus. Also this substance produces an indescribable laxative effect.

In case of drug overdose, gastroenteritis may occur.