Tablets "Serrata": instructions for use. "Serrata": reviews

Is it effective such a medicine as "Serrata"? We will provide feedback on this medication in the materials of this article. Also you will learn about how much this drug costs, how it should be used, whether it has contraindications and under what diseases it is prescribed to patients.

Composition, packaging, form

What substances are included in the substance under consideration? What does this tell us about the instructions for use? "Serrata" contains an active element, such as serratiopeptidase. As additional substances, this drug includes sodium starch glycolate, light magnesium carbonate, lactose monohydrate, magnesium stearate and cornstarch.

In the sale of the said medicament comes in the form of tablets, which are covered with an enteric coating. They are placed in the cell packs, which are embedded in cardboard boxes.

Pharmacological properties

What features are inherent in this drug? What does the instruction for use say about this? "Serrata" is an anti-inflammatory, anti-edematous and fibrinolytic agent. What is the principle of its operation?

Serratopeptidase is an enzyme exhibiting a proteolytic action that has been extracted from an intestinal bacterium of a non-pathogenic nature (Serratia E15). This group of microorganisms quite quickly splits bradykinin and fibrin, as well as other mediators of inflammation. Moreover, it exhibits anti-inflammatory and anti-edematous function. This is due to the release of painful amines from inflamed tissues, which is characterized by an analgesic effect.

Instructions for use ("Serrata" is a universal medicinal product) reports that this medication is able to quickly penetrate into the places that are subjected to the inflammatory process and to lyse necrotic tissues and their decay products.

Also, the agent under consideration reduces hyperemia, catalyses the uptake and activity of antibiotic agents. In addition, it lowers the viscosity of saliva and promotes the dilution of nasal secretions, facilitating their excretion.

Alpha-2-macroglobulins of blood and serratiopeptidase form an active complex in a ratio of 1: 1. This leads to masking the antigenicity of the enzymes without losing their pharmacological activity. When the enzyme passes to places of inflammation, as well as into exudate, the concentration of serratiopeptidase in the blood decreases.

Properties of the medicament

Due to the splitting of serotonin, histamine and bradykinin, serratiopeptidase reduces the dilatation of capillaries and reduces their permeability. It also promotes inhibition of plasmin blockers, improving their fibrinolytic activity.

After reducing microcirculation and eliminating swelling, sputum is successfully separated.

Active, as well as additional substances of this drug are enclosed in an enteric membrane. That's why the "Serrata" tablets do not break down in the stomach.

Pharmacokinetics

Where is the "Serrata" drug absorbed? The instruction informs that the process of absorption of this medication occurs in the intestine. In the blood, its maximum content is found after 60 minutes. A small amount of medication is excreted along with the urine.

Indications for use

Thanks to the versatile action, the medicinal product "Serrata", the price of which is indicated below, is prescribed for the treatment of various diseases in completely different fields of medicine:

• In surgical practice and traumatology this medication is used for fractures, dislocations, sprains and other injuries. In addition, it is often prescribed for edema, including postoperative. Also, people take pills to prevent possible rejection of the transplant.
• In the otorhinolaryngological practice, Serrata, which is positive in nature, is prescribed for otitis, sinusitis and other inflammatory processes (including VDP), which are manifested by difficulty in separating sputum and increased mucus, and also in order to improve the absorption of antibiotic agents.
• In plastic surgery, Serrata tablets are used to increase microcirculation in order to prevent probable rejection of the graft, as well as to reduce swelling after the operation.
• In dermatology, this medication is recommended in the presence of acute dermatoses, which occur with pain syndrome.
• In gynecology, the drug in question is used to eliminate puffiness of the mammary glands due to various diseases. Also this agent is prescribed for an accelerated process of resorption by hematomas, including mastitis.

Contraindications

What are the contraindications of the "Serrata" tablets? The use of this medicine is prohibited:

• When hypersensitivity to serratiopeptidase, as well as other components of the drug;
• With pathological conditions that lead to an increased risk of bleeding or bleeding disorders.

Dosage and instructions for use

"Serrata" (tablets) is prescribed only inwards. In a day, this drug should be taken in an amount of 30 mg, that is, 1 tablet three times.

The use of food has no effect on the absorption and efficacy of the drug. The tablet "Serrata" must be swallowed whole. In no case can it be chewed, as this will damage its enteric membrane. Drink the medication with plain water.

Different types of disease, and also the degree of their severity, require correction of the daily dose of the medicine in one direction or another.

To select the minimum effective dose and determine the duration of its intake should only the attending doctor, based on a specific situation.

Side effects

What side effects can the Serrata medication cause? The instruction informs, that at reception of this preparation in rare or infrequent cases disturbance of a chair, pains in GASTROINTESTINAL TRACT, a nausea and vomiting is observed.

People who are predisposed to bleeding may develop frequent nasal bleeding and the appearance of blood in the sputum.

In some cases, this drug can trigger allergic reactions, which manifest as itching or rashes on the skin, as well as hives.

Overdose with pills

Taking high doses of "Serrata" tablets can cause an increase in the above-listed side effects, and in some cases even lead to the formation of internal bleeding. In this case, you must refuse to take the medication and conduct symptomatic therapy.

Drug Interactions

With the combination of serratiopeptidase and anticoagulants, the action of the latter is enhanced. If it is necessary to simultaneously take these medications, the patient must be under regular supervision of an experienced specialist who can adjust the dose of anticoagulant.

Special Recommendations

This drug has a direct effect on blood coagulability. Therefore, it should be used with extreme caution, especially when treating with anticoagulants, as well as with a person's predisposition to bleeding and pathologies of blood clotting.

Particular care should be exercised when prescribing serratiopeptidase to people with painful kidney and liver conditions.

Reviews and the price of the drug

How much does the "Serrata" medication cost? The price of this drug in the amount of 10 tablets is 100-120 rubles.

Reviews about this tool are more positive. Doctors say that this is a universal medicine that can be used in the treatment of inflammatory processes in surgery, traumatology, gynecology, etc.

Patients are satisfied with the results of therapy. They talk about the high effectiveness of this remedy, especially when combined with antibiotics.