Co-deiron

The co-deiron is designed for people who suffer from hypertension. This combination drug contains hydrochlorothiazide (thiazide diuretic) and lisinopril.

The development of arterial hypertension is due to several factors, one of which is a delay in the body of the fluid. Dichlorothiazide is considered to be the most mild in a group of diuretics, significantly contributing to the removal of excess fluid, reducing the cardiac load and normalizing elevated blood pressure.

Such a combination of components causes the maximum effect with minimal doses of the drug K-diroton. According to some studies, the use of lisinopril in combination with a diuretic preserves the life of every ninth patient. In addition, the use of a combined agent of Co-dirolone prevents repeated hospitalizations.

The medication is often prescribed to patients with hypertension accompanied by pathology. This is due to the clinically proven ability of the drug to slow the development and progression of diabetic nephropathy in the initial stage. The di-ditron can also be administered to patients with diabetes mellitus, who are overweight.

Lizinopril has an antihypertensive effect, which is prolonged and intensified when a diuretic is added in a low dose.

The combination of a diuretic and an ACE inhibitor has a pronounced antihypertensive effect, independent of the patient's sex, age, blood level of the potassium.

In addition, such a combination is much less likely to cause lipid, carbohydrate and purine metabolism disorders, as well as hypokalemia. It should also be noted that this combination is the only one that does not increase the load on the liver.

The use of combined medicines can significantly reduce the number of tablets and the frequency of their intake, thereby improving the patient's commitment to strict adherence to the therapeutic regimen.

Co-deiron. Instructions

The medication is taken internally. The daily dose is 5-10 milligrams of lisinopril in combination with 12.5 milligrams of hydrochlorothiazide. If necessary, the dosage of lisinopril is increased to 20 mg in combination with 12.5 or 25 milligrams of hydrochlorothiazide.

For patients with renal insufficiency in a chronic form, taking the drug is possible after choosing the dosage of its individual components.

Taking medication can cause side reactions in the form of frequent headaches and dizziness. The less frequent manifestations of adverse reactions include a decrease in blood pressure of a pronounced character, chest pain. In rare cases, tachycardia, orthostatic hypotension, bradycardia, myocardial infarction, signs of heart failure are noted .

Adverse reactions from the digestive side are manifested as vomiting, dryness of the oral mucosa, nausea, dyspepsia, diarrhea, pancreatitis, hepatitis, jaundice, anorexia, and taste changes.

Side manifestations of the central nervous system are expressed in the lability of mood, paresthesia, attention deficit disorder, drowsiness, increased fatigue, convulsive muscle twitching.

Patients with medication may also experience bronchospasm, dyspnea, apnea.

Possible allergic manifestations on the skin in the form of itching, rash, hives, alopecia, sweating, photosensitization. In addition, the allergy may be manifested by swelling of the extremities, face, tongue, lips, larynx or epiglottis, fever, eosinophilia, vasculitis, positive results on antinuclear antibodies.

In a number of cases, thrombocytopenia, agranulocytosis, leukopenia, neutropenia, anemia are noted.

Adverse reactions can also occur in the genitourinary system. These include anuria or oliguria, decreased potency, uremia, impaired renal function, acute renal failure.

Other adverse manifestations include myalgia, dry cough, exacerbation of gout, arthritis or arthralgia.

Co-deiron. Analogues

To such drugs include Akkudid (tablets), Ampliton (tablets), Amprilan (tablets), Vazolong (capsules), Amprilan (tablets), Co-perineva (tablets), Capozide, Korenitek and other drugs.

The administration of medicines is carried out only under medical supervision.