Riboxin, instructions for indications, dosing, side effects and contraindications

"Riboxin" is released in the form of tablets or a solution for intravenous administration. The active substance of the drug is inosine, part of a group of those pharmaceuticals that normalize myocardial metabolism, reduce tissue hypoxia.

"Riboxin", the instruction indicates, eliminates arrhythmia, enhances metabolic processes in the myocardium, improves oxygen circulation in the body. Inosine regulates the energy balance of the myocardium, restores coronary circulation, prevents complications after intraoperative kidney ischemia. "Riboxin" is involved in the assimilation of glucose, which can affect the metabolic processes during hypoxia, even in conditions of deficiency of adenosine triphosphate.

"Riboxin", the instruction indicates, activates the action of pyruvic acid, thus providing tissue respiration; Stimulates the synthesis of nucleotides. The drug enhances the work of some of the enzymes involved in the Krebs cycle. Inosine penetrates into the cells, increases the intensity of contractions of the heart muscle, promotes relaxation of the myocardium during the performance of diastolic function, as a result, the volume of feeding blood increases.

The drug reduces the formation of platelets, increases the regenerative capacity of tissues, for example, the mucous membranes of the stomach and intestines, the myocardium.

Riboxin, indications for use

The drug is intended for the complex treatment of adults with ischemic heart disease, during the rehabilitation period after myocardial infarction, with heart rhythm disturbances, which are caused by the use of cardiac glycosides.

Inosine is prescribed for many hepatic diseases: hepatitis, cirrhosis, fatty degeneration of the liver (as a result of alcohol abuse, drugs); With urocoppororphy.

"Riboxin", instructions for dosing

The drug in tablets is recommended for adults before meals.

The daily dose is chosen from 0.6 g to 2.4 g. The daily dose is gradually increased from 0.6 g with tolerability on the second or third day to the recommended 1.2 g, and if necessary, established by the attending physician - up to 2.4 g, dividing it into three doses.

The length of the course depends on the nature of the indications, varies from 4 weeks to 1.5, and even 3 months.

With urokopprofirii appoint a daily dose of the drug in 0.8 g, take 200 mg of inosine 4 times. The medicine "Riboxin" is taken within 1 to 3 months.

With intravenous administration of a jet or drop method, the initial dose is 200 mg once, then increased to 400 mg, dividing by 1-2 drops per day. The doctor sets the course of treatment individually, depending on the patient's condition.

"Riboxin", instruction for side effects

In rare cases, there were allergic reactions, which can manifest hives, itching, flushing of the skin. Negative phenomena disappear after discontinuation of the drug.

In isolated cases, the intake of inosine increased the amount of uric acid in the bloodstream. As a result of prolonged admission, patients complained of exacerbation of gout.

"Riboxin", instruction for contraindications

Do not prescribe inosine drugs to people with hypersensitivity to one of the components of the drug, with gout and hyperuricemia.

There are contraindications to the use of "Riboxin" by patients suffering from fructose intolerance, with a syndrome of impaired glucose and / or galactose absorption, with a deficiency in the body of sugar and / or isomaltase.

Treatment with inosine patients with renal insufficiency or diabetes mellitus is carried out only under the supervision of a doctor, prescribing medication requires caution.

The effect of the drug on the development of the fetus in pregnant women is not established, so treatment with "Riboxin" during pregnancy is contraindicated. The safety of the use of inosine by women who are breast-feeding infants is not established. Therefore, when appointing "Riboxin" to nursing mothers, it is recommended to abandon breastfeeding.