Complex "Glucosamine-chondroitin": instructions, reviews

Osteoarthritis, osteochondrosis and other joint diseases occur not only in the elderly, but also in quite young and mature people. To restore cartilaginous tissues and prevent their destruction, specialists recommend taking the complex "Glucosamine-chondroitin". Reviews about the drug will be presented below. Also, you will learn about how the medication should be used, what is included in its composition and whether it has contraindications.

Composition, form of the preparation and its packaging

In what form is the preparation "Glucosamine-chondroitin" (complex) manufactured? Capsules are the only form of this drug. Its active ingredients are glucosamine hydrochloride and chondroitin sodium sulfate. Also in the composition of the drug are auxiliary compounds in the form of polyvinylpyrolidone low molecular weight medical, sodium croscarmellose, aerosil, sodium starch glycollate and magnesium stearate.

This medication is available in a vial that is placed in a cardboard box.

Characteristics of the remedy

What is the complex "Glucosamine-chondroitin"? According to experts, this is a combination medicine that is designed to restore cartilage.

The effect of the drug in question is due to the components that are included in its composition. Let's consider their features in more detail.

Chondroitin sodium sulfate is a high molecular weight mucopolysaccharide. He takes part in the construction of cartilaginous tissues. Also, this substance reduces the effect of enzymes that destroy cartilage, and helps in their recovery, contributing to the normalization of the joints.

In the first days of taking this medication, the inflammatory process decreases noticeably, and the degeneration of the cartilaginous tissues slows down.

With osteoarthritis of the joints of chondroitin sodium, sulfate helps to reduce pain. As a result, the need for admission of the NSAID disappears.

As for glucosamine hydrochloride, it acts as a chondroprotective agent. This substance has an effect on the biological synthesis of hyaluronic acid and proteoglycans, and also eliminates the deficiency of glycosamin.

It should be noted and the fact that in the synthesis of chondroitinsern glucosamine acid hydrochloride is able to activate the fixation of sulfur. In addition, this element selectively affects articular cartilage, inhibiting the formation of enzymes and radicals (superoxide), which damage tissues, and also prevents the synthesis of glycosaminoglycans and prevents the damaging effect of glucocorticoids on chondrocytes.

Kinetics of the drug

A single dose of capsules in a standard dose contributes to the maximum concentration of chondroitin sodium sulfate in the blood after 3-4 hours.

This substance is excreted through the kidneys in about a day. Its bioavailability is 13%.

As for an ingredient such as glucosamine hydrochloride, it is absorbed in the intestine. About 25% of this component falls into cartilage and joint membranes (synovial). Part of this drug is biotransformed in the liver, forming urea, water and carbon dioxide.

Indications

In what cases is the patient recommended to take the drug "Glucosamine-chondroitin"? The complex, whose composition was presented above, is actively used for the treatment of diseases of the joints and spine, including osteoarthritis, intervertebral osteochondrosis, arthropathy and spondylosis.

Also, this medication can be used to restore the patient after fractures.

Contraindications

What are the contraindications for the complex "Glucosamine-chondroitin"? It can not be used when:

• Tendency to bleeding;
• Personal intolerance of basic and additional substances;
• Diabetes mellitus;
• Breastfeeding;
• Pregnancy;
• Marked violation of the liver or kidneys;
• Phenylketonuria;
• Thrombophlebitis.

It should also be noted that this tool is not assigned to children.

The preparation "Glucosamine-chondroitin" (complex): instruction

The drug is intended for oral administration. Capsules can not be chewed and broken. They are swallowed whole and washed down with water.

For a better therapeutic result, the medication should be taken half an hour before a meal.

The duration of therapy and the exact dosage of the medicine is determined only by a specialist (depending on the nature and severity of the disease).

For adults, the drug should be taken every day 2 capsules twice a day. Three weeks after the start of therapy, the dosage is reduced to 1 capsule per day.

As a rule, treatment with this drug lasts about two months. But to obtain a sustainable effect, experts recommend taking the drug for about six months.

During such therapy it is forbidden to drink alcohol. In addition, it is required to reduce the consumption of sugar.

Adverse events

The complex "Glucosamine-chondroitin" can cause the following side reactions:

• Pain in the epigastric region, hives, vomiting, skin itching, diarrhea;
• Nausea, dermatitis, flatulence, insomnia, erythema, constipation, swelling;
• Dizziness, fatigue, drowsiness, general weakness, skin rash, headache.

If such symptoms occur, you should stop taking the capsule and immediately consult a doctor.

Drug Interactions

The complex "Glucosamine-chondroitin" in combination with tetracyclines can lead to an increase in the absorption of the latter. When the drug interacts with lemomycetin and semisynthetic penicillins, on the contrary, their degree of absorption decreases.

This medication reduces the need for NSAIDs, GCS and pain medications.

Treatment with this drug is more effective when included in the patient's diet products with vitamins C and A, as well as salts of copper, manganese, selenium, zinc and magnesium.

Reviews

Now you know what the drug "Glucosamine-chondroitin" (complex) is used for. The instruction of this medication was also presented above.

Most patients suffering from joint diseases speak of the effectiveness of this medication and a convenient form of release.

It should also be noted that the drawbacks of this drug include its high cost and side effects arising from the digestive system.