'Triampour' preparation: instructions, reviews

"Triampur" is a combined remedy, the effect of which is explained by the action of the components included in it. It has diuretic and hypotensive properties. Has in its composition hydrochlorothiazide, which is a diuretic with an average strength of action and at the same time a substance that contributes to the conservation of potassium.

Composition and form of the drug "Triampour"

The instruction informs, that in one tablet of a preparation contains

Active ingredients in the composition of:

- hydrochlorothiazide in the amount of 12.5 mg,

- triamterene - 25 mg;

Excipients:

Lactose monohydrate;

- potato starch;

- polyvidone K25;

- silicon dioxide highly dispersed;

- sodium starch glycolate;

- magnesium stearate.

Tablets are packed in bottles of 50 pieces.

Indications for the use of the medicine "Triompur"

The instruction indicates the use of the drug in arterial hypertension, edematous syndrome of various origins (with chronic heart failure, kidney pathology, liver).

Quite often in practice, the drug "Triampur" for children up to one year is prescribed as a diuretic with ICP (increased intracranial pressure).

Contraindications

It is not allowed to apply when:

Hypersensitivity;

- kidney failure;

Anuria;

- acute glomerulonephritis;

- pronounced violations of the liver;

- non-amenable disorders of electrolyte metabolism: hypokalemia, hyperkalemia, hypercalcemia, hyponatremia;

- Hypovolemia.

Method of application of the medicine "Triompur"

Instruction prescribes to swallow the drug after eating, do not chew and drink with a small amount of liquid. Doses are determined by the doctor for each patient individually. For adults and children weighing more than 50 kg an approximate therapeutic dose of -2-4 tablets - two doses / day. As maintenance therapy - one tablet / day.

Pregnancy and lactation period

The drug should not be used during pregnancy, and for the period of treatment should stop breastfeeding.

Interaction with other drugs

Antihypertensives and diuretics , barbiturates, tricyclic antidepressants, vasodilators, phenothiazines stimulate the hypotensive effect; And the NSAID, on the contrary, is weakened.

The medicine "Triampur" (the instruction emphasizes this) weakens the effect of antipodal, antidiabetic drugs, epinephrine and norepinephrine. But it increases the toxic effect of lithium, the side effects of salicylates on the central nervous system, curare like relaxants, glycosides, cytostatics.

Side effects  

"Triampur" can cause negative effects in the nervous system with symptoms of ataxia, drowsiness, headache, nervousness, etc.

In the cardiovascular system, its use sometimes causes changes in the ECG, palpitations, lowering of blood pressure, orthostatic hypotension , etc.

Side effects in the gastrointestinal tract manifest in the form of nausea, vomiting, diarrhea, sometimes - pain in the epigastrium, and in some cases - jaundice, hemorrhagic pancreatitis , etc.

In the metabolic process, substances are possible

- violation of electrolyte equilibrium, metabolic acidosis;

- increased cholesterol, glucose, triglycerides;

- dehydration, hypovolemia, etc.

Purpose of the drug "Triampur" for children: feedback  

Despite the fact that the instruction does not recommend the use of the drug in children under 18 years of age, in modern medical practice, this medication is often used to treat ICP in children under one year of age.

After analyzing a large number of reviews on the use of the drug Triampur in children under one year, one can come to the following conclusion. In the overwhelming number of cases with ICP in children, this drug has proved to be very effective. There is a significant amount of positive feedback from moms on the use of this medication in the treatment of children. But since this drug has a fairly large number of contraindications, as well as no fewer possible negative effects, then it should be used only after the appointment of a doctor. When the first signs of side effects appear, you should immediately consult a doctor.