"Theofedrine": instruction. Tablets "Theofedrine": reviews, price

How should I use Teofedrine? Instructions for the use of this tool are described in detail in the article presented. It also indicates how much this drug is worth, what it is intended for, what side effects, analogues and contraindications it has, what is included in the composition, etc.

Composition, form of production, packaging

In what form is the drug Teofedrine manufactured? The instruction of this medicine says that it is issued only in the form of tablets. They have a white or beige color, as well as a flat-cylindrical shape. Each tablet has a chamfer and inclusions.

What substances does the "Theoferrin" medication include? The composition of this drug is as follows:

• Active elements: paracetamol, theophylline, cytisine, phenobarbital, ephedrine hydrochloride, caffeine and belladonna extract.
• Additional substances: stearic acid, potato starch, povidone and calcium stearate.

Thus, it can be safely concluded that the drug "Theoferrin H" is a combined drug.

Tablets are on sale in contour squares, which are placed in packs of cardboard.

pharmachologic effect

The drug Teofedrine, the price of which is listed below, is a combined remedy. It has an antispasmodic and bronchodilator effect. These properties are given to a combination of methylxanthine derivatives (caffeine and theophylline) with m-cholinolytic atropine and sympathomimetic ephedrine, which are the main acting elements of the belladonna extract.

As for phenobarbital, it eliminates the excitation of the nervous system.

Properties of the medicine

All bronchodilator drugs, including the drug "Theoferrin", are similar in their principle of action. This means increases the clearance of the bronchi, reduces pressure in the small circle of blood circulation, and also dilates the vessels of the lungs, coronary vessels, stimulates the respiratory center, exerts a diuretic effect (moderately pronounced), increases renal blood flow, strength and heart rate.

One can not help saying that because of the presence of a substance such as paracetamol in the composition of the drug, it has an analgesic and antipyretic effect.

Pharmacokinetics

Is the drug "Theoephedrine" well absorbed? The instruction says that after taking the tablets inside, their active substance is absorbed fairly quickly from the digestive tract.

The highest concentration of the drug in the blood is achieved after 60 minutes. Formed metabolites of paracetamol are excreted for 1-4 hours (along with urine). The half-life of the unchanged drug from the plasma is approximately 3 hours. If the kidneys and liver fail, and in case of an overdose, this indicator may increase.

The maximum concentration of theophylline in the blood is reached approximately 2.5 hours after taking the tablets. Its half-life is 11 hours.

The connection of atropine with plasma proteins reaches 18%. About 50% of this substance is excreted together with urine.

As for ephedrine, it is also well absorbed from the digestive tract, creates and maintains the necessary therapeutic level of the drug in the blood. Metabolized this substance in the liver, and excreted together with urine.

Indications for use

For what purposes can tablets be prescribed? Teofedrine? Most often they are used as an auxiliary drug for diseases of the respiratory system, which are accompanied by bronchospasm. Also, the medicine is prescribed for:

• Bronchial asthma;
• Chronic bronchitis (obstructive);
• Emphysema of the lungs.

Contraindications for use

As a rule, bronchodilators, including the drug "Theoferrin", are not prescribed to patients when:

• Angina pectoris;
• Heart failure of a chronic nature;
• Violation of the coronary circulation;
• Angle-closure glaucoma;
• Disturbance of the rhythm of the heart;
• Hyperplasia of the prostate;
• Hyperthyroidism;
• Epilepsy and other convulsive conditions;
• Arterial hypertension;
• Pregnancy;
• In childhood (only up to 18 years);
• During lactation;
• Hypersensitivity of the patient to the components entering the drug.

It should also be noted that this medication is used with particular caution in diabetes mellitus, renal and hepatic insufficiency, urination disorders, and addiction to drug dependence.

Theophedrine medication: instructions for use

The considered agent is taken orally. To stop attacks of bronchial asthma, it is used as an auxiliary. The drug is taken once for 2 tablets per day. If necessary, the agent can be prescribed 2-3 times a day. The maximum daily dosage is 3 tablets.

For prophylaxis, medication is taken orally by half or a whole tablet after a meal (once a day).

To avoid disturbance of night sleep, taking medication is carried out in the morning or during the day.

The duration of treatment with such a drug depends on the nature, as well as the characteristics of the disease and the effect.

Adverse events

Adverse reactions after taking the drug in question occur infrequently. However, in some cases, the patient may experience the following phenomena:

• Heart rhythm disturbances and tachycardia.
• Mental excitement, headaches, tremors, insomnia, sleep disturbance.
• Nausea, decreased appetite, vomiting, heartburn.
• Dry mouth, urinary retention, increased sweating, allergic reactions.

Overdose

When improperly taken tablets (in higher doses), they can cause the following symptoms of acute poisoning: stomach pain, nausea, epileptic seizures, vomiting, visual impairment, insomnia.

It should also be noted that ephedrine, taken in a high dose, quite easily leads to an increase in glucose in the blood. Lethal dosage (with oral administration) leaves 1 g.

As for paracetamol overdose, in this case the patient can develop hepatonecrosis, increase prothrombin time, and increase the activity of liver transaminases. Such effects occur after taking more than 10-15 g of said substance.

As treatment for overdosage, gastric lavage, artificial vomiting and symptomatic therapy are used.

Drug Interactions

• Beta-adrenoblockers, carbamazepine, indirect anticoagulants, furosemide, cimetidine, antibiotics, verapamil, fluoroquinolones, MAO inhibitors, GCS and hormonal contraceptives are able to increase the concentration of theophylline in the blood and increase the risk of adverse reactions.
• Extract krasavki weakens the effect of anticholinesterase drugs and m-holinomimetikov.
• Paracetamol increases the properties of anticoagulants. Hepatotoxic effect of paracetamol increases with the simultaneous use of phenytoin, barbiturates, rifampicin, carbamazepine and zidovudine.
• With the combined use of ephedrine with MAO inhibitors, severe hypertensive crises occur. It should also be noted that ephedrine weakens the properties of opioid analgesics and other medications that depress the nervous system.
• With the simultaneous use of a bronchodilator with non-selective beta-blockers, the effect of the former worsens.

Theophoodrin medication: analogues and cost

With the impossible use of the drug "Teofedrine" doctors prescribe analogues of this drug. The most effective and popular are the following medicines: Bronchophillin, T-Fedrin and Trifedrine IC.

The listed preparations have their own peculiarities, in connection with which they should be used only after appointment by a specialist.

How much are Teofedrine tablets? The price of this medication is not very high. Its approximate cost is 240 Russian rubles. In this case, it should be borne in mind that it is quite difficult to purchase such a drug in pharmacies. It is very rarely delivered, and that is why it is often replaced by existing analogues.

Reviews about the drug

Most of the patients who have ever taken this drug say it is highly effective. However, some people complain that doctors prescribe to them such a potent drug with great reluctance.

It should also be noted that there is a huge amount of feedback that this medication is capable of causing psychological dependence. In this regard, his reception should be strictly controlled by a doctor.