Odeston: instructions for use

The drug Odeston is also known as Gimecromone, it is this substance that is active in the composition of the medication. Various manufacturers of medicines produce products with the same active substance under different names. Therefore, when choosing a drug, it is recommended to target the name of the drug, which is contained in the INN registry - international non-proprietary names.

As a rule, Oeston tablets are produced by pharmaceutical companies in the form of blisters, in which 10 tablets of 200 mg are soldered. Less often, the tablets are packed in polyethylene bottles.

The drug Oeston application instruction refers to the clinical and pharmacological group of drugs that have spasmolytic and choleretic effects. Its pharmacological effect is based on the ability to exert a choleretic effect and increase the dynamics of its formation and excretion from the body. In addition, the drug has a selective spasmolytic effect in relation to the sphincter of Oddi and the bile ducts. Its significant advantage over the drugs of a similar group is that the Oeston drug maintains intestinal peristalsis in a normal state and blocks the decrease in blood pressure.

The drug helps to reduce stagnation of bile and blocks the sediment of cholesterol elements, which helps to avoid the formation of stones in the bile duct.

Therefore, the drug is indicated for the treatment of chronic cholangitis and cholecystitis, reduced secretion of bile, for preventive treatment in the postoperative period, with vomiting and constipation.

Pharmacokinetic properties of the preparation Odeston instructions for use describes the following.

After taking the medicine inside, it is absorbed rather quickly, and then it is also dynamically absorbed from the digestive tract. At the same time, Cmax is reached in the blood within two to three hours after administration.

The elimination of the drug is characterized by the fact that an hour after reaching the maximum concentration in the blood, its dose is reduced by half. The main amount of active substance is excreted through the urinary tract, up to 93% of it is excreted as a glucuronate substance, about 1.4% - as a sulfonate and only about 0.3% of the substance is excreted unchanged.

Dosage of the drug is determined by the age and nature of the course of the disease or the interests of preventive use. When prescribing the medicine inside, it is taken about half an hour before eating.

The standard dosage for adults is 200-400 milligrams (with a maximum daily dose of 800 mg). Reception is carried out 3 times during the day. The duration of taking the drug is 2-3 weeks. The child's dose is 200-600 milligrams, the intake is 1-3 times a day.

The cases of drug overdose have not been fixed at the moment, therefore there is no information about the symptoms in such cases.

Drug interaction of the drug was studied by its simultaneous administration with morphine, in this case the effectiveness of the active substance gimecromone is markedly reduced. If Odeston is used in conjunction with metoclopramide, then there is a mutual weakening of the effect in both drugs. Therefore, when taking the drug, carefully study the drug Odeston. Instruction for use warns that in the case of taking two or more medicines, there may be a mutual weakening of the effect, as well as an increase in the effect of one drug due to the action of the other. The first option - this means that the maximum effect of its reception should not wait. In the second case, there is a danger of overdose.

Do not take Odeston during pregnancy. Also, its use during feeding is not allowed, since Odeston's components can have a negative impact on the development of the child.

In the list of side effects arising from the use of Odeston, the instructions for use call allergic reactions. Nevertheless, studies have shown that with a long duration of admission, diarrhea, flatulence, burning and pain in the gastrointestinal tract can occur.

It is recommended to keep the drug in a dark, dry place, do not allow children to go to it. Optimum storage temperature - no more than 25 ° C. The maximum shelf life is three years.

The drug is allowed for over-the-counter sales in pharmacies.