Nicotinic acid (injections)

Nicotinic acid (injections) refers to specific anti-pellagra agents. In this connection, the preparation has the designation "PP-vitamin". Nicotinic acid (injections) when used in the initial stages of pellagra contributes to the elimination of its phenomena.

In addition to anti-pellagrafic properties, vitamin PP improves carbohydrate metabolism, has a positive effect on diabetes in lung forms, heart disease, liver, peptic ulcer in the duodenum and stomach and enterocolitis. Nicotinic acid (injections) possesses a vasodilating property, and also promotes healing of wounds.

PP-vitamin has a lipoproteinemic effect, reducing the level of lipoproteins in the blood.

Nicotinic acid (injections) contributes to the normalization of the brain and nervous system. In addition, there is a positive effect on the cardiovascular system, digestion. Nicotinic acid for the skin is one of the main assistants in maintaining it in a healthy state. In addition, PP-vitamin helps to ensure normal vision, is involved in improving blood circulation, reducing high blood pressure due to its vasodilating properties.

Nicotinic acid for lactation is a stimulant. Vitamin PP participates in vascular blood filling and acceleration of blood circulation in the breast.

The drug is available in ampoules.

With ischemic stroke, PP-vitamin is administered intravenously. The dosage is one milliliter of a 1% solution.

Intravenous administration should be slow. Rapid intravenous administration of the solution can provoke a significant decrease in blood pressure. Intramuscular and subcutaneous injection of nicotinic acid causes pain.

Taking the drug inside (in the form of a powder or tablets), in particular, on an empty stomach or persons with hypersensitivity, can provoke dizziness, redness of the upper part of the trunk and face, sensation of a tidal flow to the head of the blood, paresthesia (numbness in the extremities), nettle rash. As practice shows, these manifestations are eliminated independently after a certain period of time.

Intravenously the drug is contraindicated for persons with hypertensive disease in severe form (with pronounced persistent increase in blood pressure) and atherosclerosis.

If there is an increased sensitivity to nicotinic acid, the drug is recommended to be replaced with nicotinamide. An exception may be the use of the drug as a vasodilator.

In order to increase lactation, the drug is administered fifty milligrams orally up to three times a day for ten to fifteen minutes before breastfeeding.

At appointment in a lactemia it is necessary to warn the patient about possible reaction of short-term character (reddening on the face and the top part of a body, feeling of filling of mammary glands, in rare cases an itch). The purpose of nicotinic acid is recommended in combination with ascorbic acid.

It should be noted that prolonged intake of vitamin-PP in large doses can provoke the development of fatty liver. In order to prevent this complication, it is necessary to include in the diet rich in methionine (an amino acid not synthesized in the body) products or to prescribe methionine and other lipotropic (selectively interacting with fats) funds.

Nicotinic acid is included in preparations such as Vitayodourol, Xanthinal Nicotinat, Vicine, Nikoverin, Lipostabil, Spasmocor, Nikospan, and others.

The drug should be administered only under the supervision of a specialist.