"Eleflox": user manual, reviews, analogs

Eleflex is a member of the fluoroquinolones group. The drug has an antimicrobial effect. The main component of the drug is levofloxacin. The solution and tablets "Eleflox" are indicated for skin infections, infectious processes in soft tissues, septicemia, community-acquired pneumonia, prostatitis of bacterial etiology, sinusitis in acute form and other diseases of infectious nature.

Composition and form of the preparation of the drug "Eleflox"

The drug is manufactured in two dosage forms - tablets (packs of 5 and 10 pcs.), Solution for intravenous administration (100 ml bottle). The solution contains 5 mg / ml of the active ingredient. Tablets can have in their composition 250 or 500 mg of the main component.

The composition of the tablets includes some excipients: polysorbate 80, magnesium stearate, crospovidone, hypromellose, MCC (Avicel PH 101, 102).

The antibiotic "Eleflox" in the form of tablets is coated with a coating for the formation of which iron oxide (yellow, red), macrogol, titanium dioxide are used. The solution as auxiliary components contains sodium hydroxide, water for injection, hydrochloric acid and anhydrous dextrose.

Pharmacological action of the drug "Eleflox"

The active component acts depressingly on the synthesis of bacterial DNA. There are morphological changes affecting the cytoplasm, membranes, the cellular wall of microorganisms and causing their death. These processes provide bactericidal and antimicrobial effects. Some anaerobes and aerobes (gram-positive, gram-negative), other microorganisms are sensitive to the drug.

With the oral use of the drug Eleflox, the composition of this drug is rapidly absorbed into the digestive tract almost completely. When the active ingredient is dosed, 500 mg bioavailability is almost 100 percent, binding to plasma is an average of 35 percent. The medicine penetrates well into some tissues and organs. A small part of it is oxidized, deacetylated in the liver. Basically, the excretion of the drug from the body involves the kidneys.

Indications for the use of the drug Eleflex

"Eleflox", analogs are used for skin lesions, prostatitis, diseases in which the respiratory tract is affected, organs that make up the urinary system. The medication is used as an additional agent in the therapy of tuberculosis, the form of which is defined as stable.

The drug treats infectious and inflammatory diseases that result from the negative effects of microorganisms that are sensitive to levofloxacin. "Eleflox" instruction for use allows you to appoint in cases where:

• Prostatitis of bacterial etiology;
• Sinusitis in acute form;
• Intra-abdominal infection;
• Acute chronic bronchitis;
• Infectious processes occurring in the urinary tract with complications or without them;
• Infections affecting the skin and soft tissues;
• Community acquired pneumonia;
• Diseases in which ENT organs are affected;
• septicemia;
• Bacteremia;
• Tuberculosis, resistant to the action of drugs (the purpose of "Eleflox" is carried out with the use of complex therapy).

Contraindications to taking the drug Eleflex

There are a number of contraindications for the drug. "Eleflox" instruction for use does not allow you to use for epilepsy, convulsive syndrome, bearing a child and during lactation. The medication is not assigned to patients whose age is less than 18 years. Contraindications include tendon lesions, which are a consequence of quinolone therapy, and an increased sensitivity of the organism to the components of the drug. Therefore, before use, you should carefully study the composition of the drug and consult with a specialist.

During the implementation of the therapy, special attention is required to the patient for disorders in the functioning of the kidneys, deficiency of glucose-6-phosphate dehydrogenase. During treatment, elderly patients also need medical supervision.

The use of the drug Eleflex

"Eleflox", analogs are recommended to use between meals or in front of them (30 minutes before eating). Tablets can be taken exclusively in a whole form with a sufficient amount of warm water.

Basically, at the initial stage of treatment every 24 hours, the drug is taken with an interval of 1-2 hours. The dose depends on the illness, the severity of its course and the sensitivity to the medicine of the causative agent of the disease.

Usually with the clearance of creatinine, exceeding 50 ml / min, the following treatment regimens are used:

• Complicated chronic bronchitis - dose per day - 250-500 mg, course duration from one week to ten days;
• Acute leaking sinusitis - the medicine "Eleflox" (500 mg) is taken every day for ten days or two weeks;
• Community-acquired pneumonia - use of 1000 mg of medicinal product per day for 2 doses for 1-2 weeks;
• A complicated infection affecting the urinary tract - the daily dose corresponds to 250 mg of the drug, the duration of the course is slightly longer than a week, if necessary, the treatment is prolonged;
• Pathologies in which the urinary tract is affected and there are no complications - approximately 250 mg of the drug are taken about 4 days;
• Prostatitis caused by bacteria - long-term treatment is required, sometimes within 28 days with the intake of 500 mg of Elefox every day;
• Sinusitis - treatment is given in tablets at a daily dose of 500 mg;
• Intra-abdominal infection - the dose for daily use is 500 mg, the course duration for complex treatment is 1-2 weeks;
• Diseases in which the skin and soft tissues are affected - therapy with a double intake of 250 mg or 500 mg of a drug every day for not more than two weeks is necessary;
• Tuberculosis, resistant to the action of other medicines, - for complex treatment, 500 mg of the drug should be taken every day (it can be taken twice) for three months.

Patients with kidney disease at certain values of the KK (ml / min) Elefloks instructions for use can be adopted as follows:

• KK 50-20 - first take 250 mg, later - 125-250 mg (possibly divided into several receptions);
• KK 10-19 - 500 mg are taken at first day, 125 mg in 12-48 hours with further treatment;
• CC below 10 - all do the same as in the previous case, but the medicine is used more than once in 12-48 hours, and once in 1-2 days.

A dropper made from the ElefloX solution is placed for at least an hour. Further treatment depends on the patient's condition. It is possible to switch to taking the tablets in the dosage in which the dropper was placed. In cases where the human body has been subjected to peritoneal dialysis and hemodialysis, the introduction of additional doses of the drug is not required.

Treatment of elderly patients who have liver problems is performed within 48-72 hours or longer, until the symptoms disappear, complete destruction of pathogens.

If the next dose of the medicine has been missed, the next dose is given or taken as soon as possible, then they follow the established treatment regimen.

Adverse effects of Eleflex

"Levofloxacin" ("Eleflox") can provoke the development of side effects. Among the possible unwanted reactions of the body - the emergence of dysbiosis, hepatitis, toxic, enterocolitis, dyspepsia. There may be pain in the muscles, abdominal pain, headache, loose stools, cramps, tremors, and fever. With a negative reaction of the body to the drug in liver enzymes, there may be increased activity. If a side effect such as pseudomembranous colitis is found, further treatment becomes impossible.

Reception of the drug is sometimes accompanied by discoordination during the movement, the presence of emotional lability, depression and sleep problems. In some cases violations of consciousness, smell and taste are noticed. To the list of undesirable reactions include arthralgia, thrombocytopenia. Agranulocytosis, paresthesia may well develop. The patient may have leukopenia, eosinophilia.

As for other side effects during the treatment with Eleflex, the instructions for use include asthenic syndrome, hypoglycaemia, fever, porphyria in acute form, increased appetite, tachycardia, arrhythmia and a significant decrease in blood pressure (there is a possibility of collapse).

Sometimes there are allergic reactions, there is burning and itching of the skin, trembling in the limbs. Secondary infection is possible. It is not ruled out the appearance of photosensitivity, neuropathy. Detection of any side effects is an occasion to call a doctor.

Overdose of EleFlox

Since there is no antidote, an overdose requires the implementation of symptomatic therapy. Among the effective methods that help to eliminate this condition - peritoneal dialysis, hemodialysis.

special instructions

Patients who have left reviews after the treatment with ElefloX have reported cautious use of the drug in certain cases. Some patients require compulsory medical supervision.

With the disappearance of high body temperature, therapy should continue for another 2-3 days. Treatment of a seriously leaking pneumonia requires the use of several drugs, otherwise the required result may be absent.

During the therapy, it is necessary to exclude the effects of sunlight, artificial ultraviolet radiation because of the risk of developing photosensitization.

There are other nuances that require attention. Any changes in your state of health should be reported to your doctor.

Combination of "Eleflox" with other agents

Interacting with certain medicines, Eleflex increases their effect or weakens. The same can happen with the action of the drug itself. If it is necessary to treat other drugs during the therapy period, Eleflex should take into account that they may be incompatible. Any changes regarding medication should be discussed with your doctor.

The cost of Eleflex

Depending on the dosage form of the drug Eleflex, the price is approximately 760-940 rubles. For tablets in a dosage of 500 mg (No. 10). About 345-450 rubles. There is a solution for intravenous administration (100 ml).

Reviews about the product "Eleflox"

Basically, patients assess the drug positively. In their opinion, Eleflex is effective and allows curing many diseases of infectious etiology.

The drug is often prescribed to patients, if necessary, to fight at once with several pathogens.

The reviews left after therapy with the Eleflox remedy show the presence of rare cases of the appearance of negative reactions of the body. Side effects are more often expressed weakly and completely disappear when therapy is completed.

Analogues of the drug Eleflex

Medicines, the action of which is similar to what has an Elephlox on the body, exists in a huge amount. It is possible to allocate such preparations, as "Maklevo", "Leobeg", "Lebel". It is known about the possibility of using "Lefokcin", "Levofloxacin", "Glevo", "Ivatsina" as substitutes. These funds are the most common and are used if necessary to choose an analogue to the drug Eleflex. The price of analogs is lower, the effect from their use is similar.

"Eleflox" refers to serious medicines and can cause a lot of side effects. Before use, it is important to carefully read the instructions. Its use for treatment should be carried out only after the appointment of a doctor who will monitor the changes taking place in the body.