Concor - instructions for use.

Drug form of the drug "Concor": The instruction says that the drug is supplied in tablets, which are covered with a film membrane. The biconvex tablets are pale yellow and have a heart shape. On each of the surfaces there are dividing risks. Tablets are of two kinds, differing in concentration.

Composition:

Active substance:

• Bisoprolol gemifumarate - 5/10 mg (in 1 table, respectively)

Excipients:

• Anhydrous calcium hydrogen phosphate
• Anhydrous Colloidal Silicon Dioxide
• Magnesium stearate
• Microcrystalline cellulose
• Crospovidone
• Corn starch

pharmachologic effect

The drug belongs to the group of beta 1 adrenoblockers, which do not have their sympathomimetic activity. The drug also does not have a membrane-stabilizing action.

Concor reduces the activity of renin, reduces the need for oxygen in the myocardium, and lowers heart rate. It also has antiarrhythmic, anti-anginal and hypotensive effects. When the dose is increased, the drug can act as a beta 2 adrenoblocker.

On the first day of taking the drug OPSS increases, and a few days later returns to normal. With prolonged use of the drug, OPSS may be reduced.

Antiarrhythmic effect of the drug is associated with its ability to reduce the need for oxygen in the myocardium, reduce the action of the renin-angiotensin system, and stimulate sympathetically peripheral vessels.

Concor indication for use

• CHD
• Arterial hypertension
• Chronic heart failure

Side effects of concor

The instruction describes almost all the symptoms that can be caused, as a consequence of the side effects of the medication.

Side effects associated with the gastrointestinal tract:

• Vomiting
• Nausea
• Constipation
• Diarrhea
• Dryness of the oral mucosa
• Hepatitis

Side effects associated with SSS:

• Bradycardia
• Arterial hypertension
• Angiospasm
• Arterial hypotension
• Angiospasm
• Violation of AV conductivity
• Arterial hypertension
• Decompensation of heart failure

Side effects associated with the central nervous system:

• Asthenia
• Dizziness
• Headache
• Depression
• Sleep disturbance
• Increased fatigue
• Nightmares
• Convulsions
• Hallucinations

Side effects associated with the organs of vision:

• Reduction of lacrimation
• Conjunctivitis
• Visual impairment

Side effects associated with Reproductive system:

• Violation of potency

Possible allergic reactions to the drug:

• Rash
• Itching itch
• Skin redness

Side effects that can be associated with dermatological causes:

• Alopecia
• Sweating
• Psoriasis

During the course of taking the drug, you can not dramatically change the dose of the medication and terminate the medication, because this can give a complication to the heart, especially for patients with ischemic heart disease.

Contraindications to the drug "Concor"

The instruction includes a list of diseases in which taking the drug is not recommended.

• AV blockade of 2 and 3 degrees
• Collapse
• Cardiogenic shock
• Pronounced bradycardia
• Heart failure
• Sino-arterial blockade
• Acceptance of MAO inhibitors (except type B)
• Pronounced lowering of blood pressure
• COPD and severe bronchial asthma
• Raynaud's disease
• Metabolic acidosis
• Pheochromacytoma
• Age to 18 years
• Sensitivity to components

In addition, this drug must be used very carefully if the patient has a history of liver failure, thyrotoxicosis, diabetes mellitus, myasthenia gravis, kidney failure, Prinzmetal angina, psoriasis, depression.

Overdose with the drug "Concor"

The instruction says that if an overdose occurs, it is necessary to rinse the stomach, take adsorption agents and prescribe symptomatic therapy to the victim.

Drug interaction of the drug "Concor" corn

The instruction does not contain descriptions of the consequences of the interaction of concor with other drugs. Concor often enough can mutually influence the effectiveness of concomitant medications.