Avodart means. Instructions

Medication "Avodart" (analogues means "Duprost", "Dutasteride") belongs to the group of drugs for the treatment of hyperplasia in the prostate gland of a benign nature. Medicines are inhibitors of 5 alpha-reductase. The active component is dutasteride.

The drug "Avodart" instruction recommends to eliminate and prevent the progression of benign prostatic hyperplasia, alleviate symptoms, reduce the size of the prostate. The drug improves urination, reduces the risk of urinary retention of acute nature, prevents the need for surgical intervention. The drug "Avodart" can be used in combination with alpha1-adrenoblockers or as a mono drug.

The drug is contraindicated for individual intolerance to dutasteride and other components, as well as other 5 alpha-reductase inhibitors. Avodart means that the instruction prohibits children and women.

Reception of a medicine can be accompanied by some by-effects. To the negative effects of means "Avodart" the instruction refers to gynecomastia (an increase and soreness in the mammary glands), ejaculation disorder, decreased libido, impotence.

In rare cases, there may be allergic manifestations in the form of limited edema, itching, rashes, angioedema, urticaria.

The drug "Avodart" instruction recommends taking for at least six months, even if the therapeutic effect has come quickly enough from the beginning of application. Otherwise, it is very difficult to give an objective assessment of the effect of the drug.

The drug may be taken regardless of food.

Dose for adult men (in old age including) one capsule (500 mcg) once a day. Do not soften or chew the drug.

There is no need to adjust the dosage for disorders of kidneys.

Caution when prescribing should be observed for patients with impaired hepatic activity, due to the fact that the active ingredient is extensively metabolized in the liver.

In clinical practice cases of drug overdose are not described. Due to the fact that there is no specific antidote, if there is a suspicion of taking an increased amount of medication, Avodart conduct symptomatic and supportive therapy.

The active ingredient of dutasteride is able to be absorbed into the skin. In this regard, children and women should avoid contact with capsules, the integrity of the shell is broken. In case of accidental contact, immediately wash skin area.

Prior to the use of the Avodart medication, men with benign prostatic hyperplasia should undergo a rectal examination of the prostate gland.

The detection of prostate-specific antigen is an integral part of a complex of research activities aimed at detecting cancer in the prostate.

After a six-month treatment with Avodart, patients have a 50% decrease in the serum level of the prostate-specific antigen even in the presence of cancer in the prostate. After the withdrawal of the drug, the indicator returns to the baseline within six months.

The ratio of free PSA to the total does not change even during treatment with Avodart.

During the research, it was revealed that combination therapy with the drug with alpha-adrenoblocker increases the risk of developing heart failure.

Medication Avodart does not affect the ability to drive vehicles or engage in any other potentially hazardous activity.