Application of "Anafranila": reviews. Anafranil (antidepressant): a description of the drug

How many people live on our planet, so many years and there is such a thing as depression. At the same time, the number of patients suffering from such a disease is constantly increasing. Not surprisingly, since ancient times, healers have sought to find an effective remedy for this disease. Similar conditions and characteristic symptoms are treated with Anafranil. Reviews about the drug in most cases, positive.

The mechanism of action of antidepressants

The main reason for the appearance of depression in a person is hidden in a small amount of serotonin. He is responsible for a good mood. It is a neurotransmitter, produced by the pineal gland of the brain.

If a person has enough serotonin, then he feels a surge of strength, is in an excellent mood. Such a person increases resistance to stress.

However, even the most effective antidepressants can not improve the mood of a patient who is diagnosed with depression. This fact is proved scientifically.

Basic Groups

In medicine, there are many classifications of modern drugs. Consider groups of antidepressants, according to their effects on neurotransmitters:

• Selective serotonin reuptake inhibitors. Such drugs do not allow you to capture the neurotransmitter presynaptic membrane and carry it back to the cell. The most popular drugs are: "Fluoxetine", "Paroxetine", "Tselexa", "Zoloft", "Fevarin".
• Tricyclic antidepressants. The mechanism of drug exposure is similar to that described above. They are prescribed in case of intolerance of patients with inhibitors. Effective drugs of this group are: Anafranil, Norpramine, Maprotiline, Palmelor, Tofranil, Elavil.
• Monoamine oxidase inhibitors. Drugs interfere with the destruction in the body of serotonin. Thus, the number of neurotransmitters increases. Representatives of this group are drugs: "Nialamid", "Iprazid", "Tranilcipromin", "Izokaraksazid", "Pargilin".
• Serotonergic, noradrenergic antidepressants help slow the absorption of neurotransmitters by the postsynaptic membrane. This group includes drugs: Serzon, Mianserin, Desirel, Imirtazapine, Remeron.
• Inhibitors of reuptake of noradrenaline and serotonin. These drugs are the latest generation, which block the reverse capture of neurotransmitters. In addition, they have quite a few side effects. Effective medications are: "Effector", "Ziban", "Cimbalta", "Maprotiline".

Pharmacological action "Anafranila"

This drug is a tricyclic antidepressant. The active substance of the drug is clomipramine. It is an excellent antidepressant, which has a pronounced sedative effect and moderately analgesic.

The use of "Anafranil" is recommended for patients suffering from psychomotor retardation, anxiety, bad mood. Its effectiveness is confirmed even with bulimia.

Therapeutic effect occurs after 6-7 days of regular use of the medication. And the maximum efficiency is noticeable after 2-3 weeks.

Indications for use

The drug is in demand for the treatment of depressions of a different nature and type. This is the evidence for the preparation "Anafranil" instructions for use. Comments of physicians especially focus on a wide range of pathological phenomena, in which the drug is quite effective.

This antidepressant is prescribed for:

• Treatment of depression - neurotic, reactive, endogenous, masked, involutional, organic;
• Therapy of panic attacks and various phobias;
• Elimination of depressive conditions in elderly individuals provoked by severe permanent pains or somatic pathologies;
• Treatment of depressive states in schizophrenics, psychopaths;
• The fight against catalepsy (narcolepsy);
• Elimination of mood disorders of psychopathic, reactive or neurotic nature;
• Prevention of migraine;
• Treatment of senile and presenile depression;
• Elimination of nocturnal enuresis, which is not associated with other diseases.

The use of "Anafranil" is shown even to oncological patients suffering from chronic pain syndromes.

Contraindications to admission

These pills for stress and depression are not allowed for use under the following conditions:

• Allergy to the components of the drug;
• Recently suffered myocardial infarction;
• Children under 5 years;
• Pregnancy, infant feeding;
• Alcohol intoxication;
• Angle-closure glaucoma;
• Drug intoxication;
• Severe conduction disturbance.

Extremely cautious, because there may be side effects from the drug "Anafranil", prescribe this remedy under the following factors:

• epilepsy;
• Brain injury;
• adolescence;
• Reception of antipsychotics;
• Retention of urine;
• glaucoma;
• Cardiovascular insufficiency or arrhythmia;
• Adrenal gland tumor;
• Serious liver pathology;
• Hyperthyroidism;
• Propensity to constipation;
• elderly age.

Patients who take this medication must constantly monitor arterial and intraocular pressure. Individuals who use contact lenses should remember that the drug helps reduce the intensity of tearing. As a result of this effect, corneal damage may occur.

Greater attention is required by intravenous drug administration. Some patients may experience an anaphylactic shock.

Side Effects of Antidepressants

Unfortunately, medicine has not yet invented drugs that do not have undesirable reactions. Side effects of antidepressants often concern:

• Central nervous system;
• Organs of hematopoiesis;
• Endocrine system (allergy, excess weight);
• Higher nervous activity;
• of cardio-vascular system;
• Sexual dysfunction.

Side effects of the drug "Anafranil"

Undesirable reactions during therapy with this remedy are often poorly expressed. In addition, the drug "Anafranil" side effects are similar to the symptoms of depression. In most cases, during treatment, they pass as soon as the necessary effect is achieved, and the dosage of the drug will begin to decrease.

If unwanted reactions are serious or threatening the patient's life, the medication should be discontinued. Often, side effects occur in the elderly.

The following manifestations may occur:

• Drowsiness, fatigue, tremor, dry mucous, increased appetite, sweating.
• Headache, constipation, nausea, weight gain, impaired vision.
• Excessive heartbeat, hot flashes, increased muscle tone or weakness, paresthesia, speech impairment.
• Tachycardia, lowering of pressure, diarrhea, vomiting, abdominal pain, increased activity of liver enzymes.
• Noises in the ears, urticaria, rash on the skin, itching, distortion of taste.
• Sleep disturbance, hallucinations, disorientation, aggression, anxiety, memory dips.
• Heat, ataxia, convulsions.
• Puffiness, urinary retention, glaucoma, violation of intracardiac conduction.
• Anaphylactoid and anaphylactic reactions, pneumonitis, thrombocytopenia, leukopenia.

Possible consequences

Many drugs have a rather unpleasant withdrawal syndrome. In other words, as soon as the patient stops using antidepressants, the consequences of such a decision can be completely undesirable - the symptoms return. In addition, sometimes the patients exhibit sensory disorders, insomnia, nausea, overexcitation. Some people may even experience delusions and hallucinations.

Unfortunately, this is the symptomatology caused by the abrupt reversal of Anafranil. The patients' testimonies indicate the return of painful sensations. Against the backdrop of such a clinic, there is vomiting, nausea, irritability, insomnia, headache, anxiety.

That's why doctors recommend a specific scheme for taking this medication. Initially, the dose increases, and when the maximum allowable rate is reached, it slowly begins to decrease.

Opinion of doctors about the drug

The medicine "Anafranil" is in great demand. The doctors' comments testify to the high effectiveness of this remedy in the treatment of moderate depression, the fight against obsessive conditions.

Doctors, observing patients who prescribed the drug, note that this is a great rescue from anxiety, panic attacks, obsessions, aggression. The medicine allows you to eliminate a variety of phobias in patients.

In this case, patients are always warned about the undesirable consequences after taking the drug Anafranil. The doctors' testimonies indicate that side effects still occur. Along with the excellent elimination of obsessive conditions, sometimes the use of the medicine is seriously complicated. After all, some patients have speech disorders, memory problems, drowsiness and some other manifestations.

A special place is given to the need to take the drug regularly throughout (depending on the appointment of a doctor) for a period of 6 months to 3 years. Therefore, it is extremely important to take the necessary prescription from the treating doctor in time to prevent the return of unpleasant symptoms. And it can appear even with the one-day cancellation of Anafranil.

Patient Reviews

What is the opinion of patients about this medicine? Surprisingly, the favorable impact of "Anafranil" reviews patients fully confirm. The drug excellently removes obsessive thoughts, perfectly eliminates the symptoms of depression. The medicine can return people the will to live.

However, one should not forget about side effects. They, unfortunately, often make themselves felt.

Conclusion

It is important to understand that depression is far from the manifestations that are now being invested in this concept. Apathy, inhibition, bad mood, excitability, fatigue, small failures - this is only a weak reflection of the pathological process. A full-fledged diagnosis can only be made by a doctor. And only he will recommend effective antidepressants.