"Ampicillin": instructions for use, reviews. Analogues of "Ampicillin"

Manufacturers of medicines now offer a wide selection of antibiotics, antimicrobial and bacteriostatic drugs. Some of them have a wide spectrum of action, others struggle only with certain microorganisms. Such medications are forbidden to take on their own, because the consequences of therapy can be very different. Today's article will tell you about the drug Ampicillin. Instructions for use, feedback, analogues and the correct way of use will be presented to your attention.

Immediately we stipulate that the information received should not lead you to self-treatment. If you have health problems and need such serious medications as antibiotics, then you should always seek medical help. Only in this case there is a chance for a quick recovery.

Preliminary acquaintance: form of issue, cost and composition

The active substance of the drug is a compound called ampicillin trihydrate. Analogues of this antibiotic can have the same name composition or differ in components. You will learn more about them in the article. Ampicillin is most often produced in the form of tablets and powder. The latter is intended for intramuscular or intravenous administration. Preliminary solution must be prepared. How to do it correctly - describes the instructions in detail. Slightly on sale you can find a suspension.

The cost of the medicine is affordable. Ampicillin has been on the pharmacological market for a long time. You can buy it without a prescription. Tablets in the amount of 20 pieces of 250 milligrams will cost you about 20 rubles. Depending on the manufacturer, the price may slightly shift to a greater or lesser extent. You can buy a bottle of powder for injection for 15 rubles. In this case, the content of ampicillin in such a container may differ: 200, 250, 500 and 1000 milligrams.

How does Ampicillin work?

The drug "Ampicillin" refers to the antibacterial semisynthetic drugs of the penicillin series. The drug has a wide range of effects, so it is often prescribed to patients without prior sowing of sensitivity. The drug suppresses the synthesis of a bacterial cell, which has a bactericidal effect.

The active substance is effective against many aerobic microorganisms, both gram-positive and gram-negative. The medicine has a minus. He is not able to suppress the reproduction of bacteria that produce penicillinase. To my great regret, there are many such. Often, such microorganisms are formed due to improper use of antibiotics. This once again proves that you can not do self-medication, but you need to turn to the doctors for help.

Penicillin substitutes

Can I choose the analogues of Ampicillin myself? All doctors and people with medical education answer this question unanimously: it is impossible. The fact is that some substitutes have a narrow spectrum of action, they may not be effective in a particular situation. If for some reason you can not use the designated Ampicillin, new generation analogs or obsolete substitutes should be recommended by a doctor.

You already know that the drug belongs to the penicillin group. Therefore, an alternative medication is often chosen from it. If you are talking about drugs in which the active substance is ampicillin trihydrate, then you can allocate the following funds: Zetsil, Stanzacillin, Penodil, Purcillin, Pentrexyl, and so on. Recall that the drug "Ampicillin" can be produced by different manufacturers. Therefore, its trade name also changes: Ampicillin Trihydrate, Ampicillin Sodium Salt, Ampecillin Innotek.

Replace the drug can penicillin antibiotics with other active substances. In this case analogues of "Ampicillin" will contain the following active component:

  • Amoxicillin ("Augmentin", "Ecobol", "Flemoxin");
  • Phenoxymethylpenicillin ("Cliacil", "Ospen");
  • Oxacillin (Prostaflin);
  • Piperacillin ("Pitsellin", "Piprax") and others.

Another alternative: popular antibiotics

Analogues of "Ampicillin" may have other active substances. These drugs are related to other groups of antibiotics. Often they are chosen as a substitute, when the patient shows an allergic reaction. Some medicines refer to the new generation of antibiotics. So, the agent "Ampicillin" analogs has the following.

  • Cephalosporins: "Cefatoxime", "Ceftriaxone", "Suprax".
  • Macrolides: Sumamed, Wilprafen, Clatid.
  • Tetracyclines: "Minolexin," "Unidox," "Tigacil."
  • Aminoglycosides: Gentamicin, Neomycin, Streptomycin.
  • Lincosamides: "Nerolen", "Dalacin" and many others.

Indications for use and limitations in the use of Ampicillin

Absolute analogues of "Ampicillin", like the penicillin antibiotic itself, are often prescribed for bacterial lesions of the respiratory tract: bronchitis, pneumonia. The drug is used in ENT-practice with infections of the nose, throat and ear. It is prescribed for bacterial diseases of the gastrointestinal tract, the genitourinary system. Indication for use will be meningitis, sepsis, skin diseases, rheumatism.

Before using the antibiotic Ampicillin, analogues or substitutes for a new generation, it is important to read the instructions. Pay special attention to contraindications and adverse reactions. For example, the drug "Ampicillin" is inadmissible to use with high sensitivity to its components, allergies to other penicillin antibiotics. Contraindication will also be infectious mononucleosis, liver and blood diseases. The drug is ineffective against viral pathologies.

Ampicillin: instructions for use

Analogs of the drug always have a different way of use. Pay special attention to this. Incorrect use of an antibiotic entails the most unexpected consequences: from ineffectiveness of the drug to a lethal outcome. You already know that Ampicillin is available in two forms: pills and injections (you can find a suspension, but it is not so popular). How to use them correctly?

  • Pills are prescribed in a volume of 1 to 2 grams of active ingredient per day (divided into 4 divided doses). Children prescribed medication in accordance with the body weight. It is not recommended to use tablets to treat babies.
  • In the form of injections, the drug is prescribed to adults at 250-500 mg every 4 or 6 hours (depending on the infection and the severity of the condition). For the treatment of children, "Ampicillin" is used in a dose of 25 to 50 mg of the drug per kilogram of body weight. It is important to observe caution and aseptic rules when stitching.

Duration of treatment is determined individually, but it should not be less than five days. The maximum daily dose of medication for an adult is 4 grams in the form of tablets, and in the form of injections - 14.

Treatment during pregnancy and lactation

Some analogues of "Ampicillin" are allowed for use during pregnancy, but only according to the indications. In most cases, these drugs are penicillin rad. Macrolides can also be prescribed for future mothers, but this happens less often. The medicine "Ampicillin" can be used during pregnancy according to the doctor's prescription. It is necessary to refrain from taking an antibiotic only in the first trimester. To future mothers the medicine is prescribed in individual dosage according to a certain scheme.

It is proved that the active substance - ampicillin trihydrate - is able to penetrate into breast milk. Therefore, there is a probability of getting the drug into the baby's body. If there is a need for treatment during lactation, then the question of stopping breastfeeding should be addressed.

Additional information about the medicine

If you use the analog "Ampicillin" in tablets together with the original antibiotic, the effect of both drugs can significantly increase. Therefore, it is important to choose the right therapy. Do not combine Ampicillin with a new generation of antibiotics and other similar drugs that have a bactericidal effect.

Since the drug suppresses the intestinal microflora, it can cause a violation of the digestive function. Diuretics, sorbents and laxative medicines reduce the absorption of antibiotic. Ascorbic acid, on the contrary, increases it. Please note that the drug reduces the effectiveness of oral contraceptives.

Negative consequences of therapy

The drug does not belong to the new generation of antibiotics. He does not undergo advanced cleaning. Therefore, the medicine can cause a number of negative reactions. Among them the most frequent:

  • Impaired digestion, nausea, vomiting;
  • Intestinal dysbiosis, diarrhea or constipation;
  • Fungal lesions of the oral cavity, genital organs, skin;
  • Allergic reaction in the form of edema, urticaria, shock.

Allergy to Ampicillin

Analog "Ampicillin" (in injections or pills - not the essence) from the penicillin series, like the drug itself, often provokes an allergy. In this case, it can have a variety of manifestations. If you ever noticed such a reaction, you need to remember. In the future, when prescribing antibacterial drugs, be sure to report this fact to the doctor.

The most common allergy to "Ampicillin" is a skin rash. Small sores can be located throughout the body or in separate zones. It also causes joint pain and tightness of the skin. Less often there is swelling. If an allergy occurs, seek medical attention as soon as possible, do not take the next dose of the medication. Further therapy involves the use of sorbents and antihistamines. It is also necessary to choose an analogue of an antibiotic.

Ampicillin and alcohol

What else is the instruction about the medicine "Ampicillin" instruction? Analogues of the penicillin series, as well as the antibiotic described, does not recommend combining with alcoholic beverages. Such combinations increase the likelihood of side effects. In addition, ethanol in combination with "Ampicillin" has a detrimental effect on the liver and stomach. Combining chemicals can simply deactivate the action of the drug.

Despite this fact, some consumers manage to miss a couple of glasses during the treatment. Patients say that nothing terrible has happened to them. In fact, it's just luck. Perhaps the consequences will still manifest themselves in the future.

Reviews about antibiotics

What are the opinions of patients about this drug? In most cases, the drug is effective. It allows you to quickly get rid of the problem. Already on the second day of taking the antibiotic, there is a noticeable improvement. In this case, the medicine also has negative sides. Therapy with this drug is long, while there is a negative effect on other organs. Almost all patients say that with the use of "Ampicillin" tablets, there is a violation of the digestive function. For its further recovery requires a course of probiotics. This is not cheap, despite the affordable cost of Ampicillin itself.

In recent years, doctors are trying not to prescribe the described medicine. He was replaced by new improved medications. Antibiotics of the new generation undergo more thorough purification. Because of this, they rarely cause side effects, do not have a toxic effect on the patient's body. Some drugs have a combination of substances that enhance their effect, for example, "Amoxiclav" or "Augmentin".


From the article you learned about a long-invented and already obsolete antimicrobial drug called "Ampicillin". Reviews, analogues of this medicine and the way it is used - we talked about all this in detail. Despite the fact that you now know a lot about the drug, you should not self-medicate. Remember that antibiotics are completely useless (and even harmful) in viral infections. Most colds are caused by viruses. Strong to you health!

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