Trental: product description, recommendations, cautions

"Trental" - a medicine designed to enhance blood microcirculation. It is available in the form of tablets, injection solutions.

How does Trental act? Description of the drug reports that its active ingredient is pentoxifylline. This substance is a derivative of xanthine, a purine base, present in all tissues of the body. Pentoxifylline actively reduces the aggregation (clumping) of erythrocytes, increases their elasticity, thereby reducing the viscosity of the blood. It reduces the accumulation of fibrinogen in the plasma, normalizes fibrinosis. Trental helps the accumulation of adenosine monophosphate in the myocytes of the vessel walls, reduces vascular resistance, but increases the systolic volume without changing the number of heartbeats.

In addition, "Trental", the description of the drug contains this information, speeds up the metabolic processes occurring in the nervous system, significantly increases the amount of adenosine triphosphate in the brain cells. The drug normalizes the bioelectric performance.

Who is treated with Trental? Indications for use are based on the ability of the drug to improve microcirculation.

He is prescribed for treatment:

• Encephalopathy caused by atherosclerosis, a violation of the cerebral circulation.
• Dyscirculatory encephalopathy.
• Stroke (ischemic).
• Vascular impotence, other sexual problems associated with impaired blood circulation.
• Paresthesia.
• Raynaud's Diseases.
• Trophic ulcers, frostbite, gangrene, skin lesions associated with insufficient amount of incoming blood.
• Bronchial asthma, emphysema of the lungs, bronchitis.
• Loss of hearing, provoked by blood circulation disorders.
• Loss of vision caused by insufficient circulation of blood.
• Other circulatory disorders, especially those provoked by inflammation, diabetes, atherosclerosis.

Treatment with the drug should be prescribed only by a specialist, because "Trental", the description of the drug contains this information, can cause side effects.

These include:

• Pain in the stomach, spasms, nausea, upset stomach , vomiting. The occurrence of gastric bleeding due to the use of Trental is not proven.
• Heart rhythm disturbances, palpitation, tachycardia, angina attacks, hypofibrinogenemia, hyperemia.
• Anxiety, panic attacks (rarely), irritability, sleep disturbance, drowsiness, dizziness. There were rare cases of aseptic meningitis (with ultra-high doses or an unreasonably long course of treatment).
• Edema Quincke, rash, anaphylactic shock.

In order to avoid such consequences, it is necessary to take "Trental" only as prescribed by the doctor, after a thorough examination.

"Trental", the description of the drug details this, is not shown to all patients with the above diagnoses. There are categories of patients who are not recommended to prescribe this medicine.

People who are prone to bleeding, suffering from hemorrhagic infarction or hemorrhage, is not recommended to use Trental. Contraindications also apply to pregnant and lactating children, people with intolerance to the medicine.

An overdose of the drug can be fatal. With the introduction of ultra-high doses, there was a development of gastric bleeding, vomiting, and tachycardia. Often, especially after injections, exceeding the dosage, there was excitement, anxiety, loss of consciousness, convulsions.

In this case, it is necessary to urgently rinse the stomach, perform therapy, focusing on the symptoms. Control over the vital functions of patients is mandatory.

The dosage of the drug, the choice of dosage forms, the duration of treatment is determined only by the treating specialist, guided by the diagnosis and characteristics of the patient.