HealthMedicine

Thyrotropin: a conductor of metabolism

The importance and importance of thyroid hormones is known to everyone, because they are the ones that kindle the furnace of our metabolism, being extremely important for the harmonious development of the body and the effectiveness of mental activity. However, not everyone knows that the activity of the thyroid gland is controlled by the blood content of the hormone, which we call thyroid-stimulating hormone. Its output is made in the holy of holies of the brain - a small organ, a mass of a half-gram, called the pituitary gland.

However, the pituitary gland is not the most important "boss" that regulates the function of the thyroid gland. It is controlled by the hypothalamus, which produces thyrotropin-releasing hormone. In addition to the orders of the immediate "boss", the results of the activity are very important for the pituitary gland. So, if it is found that there are too many thyroid hormones in the blood , the pituitary gland stops its work. If, on the contrary, they are not enough, the secretion of thyroid-stimulating hormone increases. This is called the principle of feedback, this mechanism of regulation is very characteristic of all processes in the human body.

Thyrotropic hormone is higher than normal in a number of cases. Very rarely this is due to the activity of the largest "boss" - the hypothalamus, sometimes his tumor can provoke such a state when he does not respond to signals about an increase in the blood levels of thyroid hormones. Happens, all business in illness or disease of a pituitary body. But most often the level of thyroid-stimulating hormone rises due to the fact that there are violations at the level of the thyroid gland and it can not cope with the work intended for it. Then there is a sharp increase in the production of thyroid-stimulating hormone in a vain attempt of the pituitary gland by any means to increase the level of thyroid hormones. Also, a slight increase in the level of the hormone under consideration is observed at high stresses, when the body needs mobilization of all forces and therefore the thyroid gland is operating at full power, and the sensitivity of the pituitary to thyroid hormones is reduced. Every time a doctor sees an increase in the thyroid-stimulating hormone above the norm, he is alarmed, because this symptom can be both a cause and a consequence of disease states. Therefore, at the same time, tests for thyroid hormones are taken. Also, the level of the hormone in question rises in response to the introduction of opioid substances.

The thyroid-stimulating hormone is below normal, when the amount of thyroid hormones in the blood is increased. The thyroid gland at the same time produces them too much and its painful production of these hormones causes the pituitary to stop the synthesis and secretion of the thyroid-stimulating hormone. Also, its quantity in the blood decreases with starvation and malnutrition. It will inevitably become less with serious somatic diseases, as well as some mental illnesses, such as anorexia nervosa and bipolar affective disorder. In addition, diseases that affect the hypothalamus and pituitary gland can not be ruled out.

Thyroid stimulating hormone is produced in the same concentration in children and the elderly (except in cases of very early childhood and elderly people over 70), women and men. The hormone is produced cyclically, with the length of such a small cycle about 2 hours, this rhythm is very close to the rhythm of prolactin hormone production. It is not related to the activity of the hypothalamus, but it is assumed that there is some hidden mechanism that allows to regulate the activity of both these hormones. They are produced most intensively before bedtime, in the evening, with somatic diseases this peak is much more pronounced than in normal.

This is an unusual thyroid-stimulating hormone. Usually, he falls into the field of doctors' attention only if there are abnormalities in the thyroid gland. But he can tell very much about many things that he does not prevent himself from being very mysterious.

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