The medicine 'Baclofen'. Instructions for use

The drug "Baclofen" instructions for use characterizes as an antispastic myorelaxing drug, a derivative of GABA (gamma-aminobutyric acid). The medication differs from other similar drugs both in its pharmacological properties and in its mechanism of action. The drug is prescribed for adults and children to remove the increased tone against a background of various pathologies. About the drug "Baclofen" reviews can be found different. In general, the drug is characterized as highly effective, but has some side effects.

Expressed myorelaxing properties of the drug are associated with the ability to inhibit poly- and monosynaptic impulse transmission in the nerves, which is probably due to a decrease in the release of aspartate and glutamate (excitatory amino acids).

The drug has a moderate analgesic effect.

Against the backdrop of neurological pathologies complicated by spasticity in skeletal muscles, the drug "Baclofen" not only has a beneficial effect on reflex muscle contractions, but also contributes to a pronounced weakening of clonic seizures and painful spasms.

When taking the medication, the functional and motor activity of the patients is increased, the patients are more tolerant of active and passive kinesitherapy (manual therapy, massage, physical exercises).

The "Baclofen" medication is recommended for the removal of increased spasticity (spasticity) of skeletal muscles in various diseases. Pathologies, in particular, include alcoholism (with affective disorders), craniocerebral trauma, meningitis, cerebral palsy, stroke, multiple sclerosis. The drug is indicated for diseases of the spinal cord, traumatic, degenerative and infectious (tumors or compression in the spinal cord, spastic paralysis, paraparesis, traumatic paraplegia, transverse myelitis, syringomyelia, amyotrophic lateral sclerosis).

The drug "Baclofen" instruction recommends taking while eating.

The dosage of the drug is selected in such a way that, together with the weakening of the clone (indiscriminate contractions), spasms of the unbending and flexing muscles, the tone necessary for active movement is maintained.

"Baclofen" medication instructions for adults recommend that you prescribe five milligrams three times a day. For every fourth day, the dose is increased by five milligrams three times a day to the development of optimal therapeutic effectiveness. On average, a day can be taken from thirty to seventy-five milligrams a day. In exceptional cases in stationary conditions for a short period, the administration of the drug in a dosage of 100-120 mg is allowed.

If the patient has an increased sensitivity to medicines, lower initial doses are recommended. The increase in the amount of medication taken in these patients is slow.

The drug "Baclofen" instruction for children up to ten years of age recommends appointing 0.75-2 milligrams per kilogram per day, after ten years - 2.5 mg / kg. They start taking the drug four times a day. Daily dosage for children is selected individually.

The drug "Baclofen" is contraindicated in renal failure in the chronic phase, Parkinson's disease, psychosis, convulsions and epilepsy in the medical history, hypersensitivity.

The medicine is not prescribed during pregnancy. Due to the fact that the active ingredient of the product is able to penetrate into breast milk, when prescribing the drug to a nursing woman, it must be warned about the need to stop lactation for the duration of treatment.

As practice shows, the side effects when taking the drug "Baclofen" are observed at the beginning of treatment and are associated, in most cases, with a high dosage. If there are undesirable consequences on the background of treatment, you should contact a specialist.

Before taking the medication, you should read the annotation.