The drug "Menopur": reviews and results, instructions for use and description

A fairly large number of married couples suffer infertility. Modern medicine has great potential in solving this problem, but patients need to understand that therapy is long-term. "Menopur" is a medicinal product that is also used in the treatment of infertility. In this article we will try to understand what its mechanism of action is and what indications it has for application.

Form release and composition of the drug "Menopur"

The product is available in ampoules.

Composition: the main substance - follicle-stimulating hormone (FSH) and luteinizing hormone (LH) in the ratio 1: 1.

Additional components:

• Lactose monohydrate.
• Polysorbate 20.
• Sodium hydroxide.
• Hydrochloric acid.

Also in the kit with the drug is an ampoule with a solvent that contains an isotonic sodium chloride solution and diluted hydrochloric acid to create a normal pH level.

The drug is produced in a cardboard box, where 5 ampoules of medicine are placed and 5 - with a solvent.

As part of the medicine "Menopur" contains a special purification of human menopausal gonadotropin. It is obtained from the urine of the female half of humanity after they have had menopause. With the introduction of the woman's drug "Menopur" (reviews and results of numerous studies confirm this) there is a stimulation of the production of estrogens and the maturation of the follicles. In addition, there are proliferative processes in the endometrium.

If the drug is administered to a man, then the level of testosterone rises in his body. Also, this drug stimulates spermatogenesis, due to the effect on the cells of the seminiferous tubules.

"Menopur": indications for use

Women are recommended to take the drug with infertility due to hypothalamic-pituitary disorders, as well as to implement additional reproductive technologies for the onset of conception.

Men are also advised to use Menopur. Reviews and results of treatment confirm its effectiveness For azoospermia and oligoastenospermia, which are caused by primary or secondary hypogonadotropic hypogonadism, but only the drug must be combined with another drug of human chorionic gonadotropin - hCG.

"Menopur": the right reception for women

For women, the drug is recommended to undergo a course of injections with infertility, which is provoked by problems in the work of brain areas responsible for the production of female hormones. For each woman the dosage is selected individually. The optimal amount of the drug and the course of therapy are established only after the passage of all the studies:

• Ultrasound of the ovaries.
• Definitions of the level of female hormones in the patient's blood.
• All the necessary tests.
• Conversations with the doctor.

Initiate the introduction of the drug "Menopur" (reviews and results of treatment certificate) with 1-2 vials a day (75-150 IU). If the ovaries do not react in any way, the dose should be gradually increased until the level of estrogens begins to rise together with the growth of the follicles. After that, the dosage is kept at this level until the content in the blood of estrogens becomes the same as before ovulation. If the estrogen level rises too quickly, the dose is reduced.

In order to induce ovulation every other day, as a last resort, two after the last injection of "Menopur" once injected 5 000-10 000 IU hCG.

"Menopur" for the strong half of humanity

" Menopur" for men (reviews and application results indicate this) are recommended for stimulation of the process of sperm formation. Enter the medication in an amount of 1,000-3,000 IU hCG three times a week until the testosterone level in the blood is normalized.

After that, the drug should also enter the male body three times a week, but in the amount of 1-2 vials (75-150 IU) for several months.

Contraindications for use

"Menopur" is an excellent drug, but it has its own contraindications for use, which every patient must know before reporting to therapy in order to inform the doctor about them and, together with him, to choose a replacement or the correct dose. It is not recommended to take the medicine with the following pathologies:

• Problems in the work of the adrenal and thyroid gland.
• Tumor neoplasms in the hypatalamo-pituitary region.
• Hyperprolactinemia.
• An increase in the size of the ovaries or the presence of cysts that are not associated with the symptom of polycystic ovaries.
• Bleeding from the vagina of an unexplained nature.
• Anomalies in the development of genital organs.
• Myoma of the uterus, which is not compatible with the bearing of the child.

• Cancerous growths in the uterus, ovaries, breast glands.
• Insufficiency of the ovaries of the first stage.
• Pregnancy and lactation.

Men are not recommended to take the drug "Menopur" (reviews and results of treatment are confirmed) with a cancer neoplasm in the prostate gland or in the presence of other androgen-dependent tumors.

"Menopur" for stimulation of superovulation

Before embarking on IVF, women are prescribed a drug that will help stimulate superovulation. There are a lot of such medicines: "Diferelin", "Cetrotide", "Puregon" and many others.

"Menopur" for a man in the IVF protocol is considered one of the effective drugs, which showed good results after the procedure. Correctly pick the protocol will help the doctor in every single case. The specialist will take into account all the conducted studies and will select the correct course and dosage, which will help to increase the positive result from the IVF procedure several times.

"Menopur" and its side effects

After the use of the drug "Menopur" reviews and results of IVF in most cases, positive, this allowed to make happy many families.

However, one must remember that he also has side effects:

1. On the part of the digestive system: vomiting, nausea and flatulence.
2. On the part of the endocrine system: a syndrome of ovarian hyperstimulation, an increase in the excretion of estrogen in the urine, pain in the lower abdomen. Men can have gynecomastia.
3. On the part of metabolic processes of the body: blood thickening, water-electrolyte failures, ascites and hydrothorax.
4. In addition, during the period of application of the drug many patients observed manifestations of an allergic reaction, as well as edema and itching at the site of the injection.

"Menopur": special instructions for use

Before beginning treatment, every woman and man should know that there are many restrictions and reservations. All this in detail informs the instructions for use attached to the medicine "Menopur" . The price (reviews mark it as high enough, but not transcendental) varies between 1500 rubles per injection. However, the drug is effective and allowed many families to experience parental happiness.

Before use, it is necessary to exclude the syndrome of ovarian exhaustion or resistance, extragenital endocrinopathies.

Also, every woman who is being stimulated with "Menopur" (the patients' reviews specifically note this fact) should know that the result can be a multiple pregnancy.

If the patient has signs of ovarian hyperstimulation, treatment should be stopped urgently. This can signal pain in the lower abdomen, as well as ultrasound. During therapy, you need to monitor the level of hormones every day and make ultrasound of the developing follicle.

If the pregnancy has already occurred, the symptoms of excessive hyperstimulation can significantly increase and be observed in the patient for quite a long time, which can be a serious threat to her life.

In the period of therapy in men, with a high concentration of FSH in the blood, menotropins will not show positive results.

"Menopur": reviews

Nowadays, a lot of women can not get pregnant naturally, which is why they agree to the IVF procedure, which gives a chance to have a child. But it does not give 100% of the result from the first time, so you have to carry out the procedure several times. But not every woman has such an opportunity, since it is not cheap. In order to give women the opportunity to become pregnant the first time as a result of IVF, the preparation "Menopur" 300 ME was developed. The reviews and the results of therapy are overwhelmingly positive. The medication increases the chances of getting pregnant several times.

The drug gives very good results after therapy, the responses of the patients are only positive, the only thing that scares many of them is the multiple pregnancy, which can occur after the course of therapy with the drug "Menopur". There are also many contraindications and side effects, but if you are always under the supervision of a doctor who will monitor the patient's condition and control the dose, then all the undesirable manifestations will not be terrible.

In conclusion, I want to say: the desire of a woman to have a child is so huge that she is ready to go to anything you want to know about the happiness of motherhood. Therefore, the therapy "Menopur" with all its side effects is not terrible for her. But it is worth remembering that an ill-considered decision and uncontrolled use of a medicine can lead to very serious and irreparable consequences. Only the doctor should go with the woman along this path and do everything possible to get a positive result.