The drug "L-thyroxine." Reviews of specialists. Instructions

The drug "L-thyroxine" in its composition has levothyroxine, similar in action to thyroid endogenous human hormones. The substance, after being ingested, is metabolized to lyotyronine. And he, in turn, penetrating into the cells, regulates their development, has an effect on the metabolism. The drug "L-thyroxine" is able to act in the mitochondria on oxidative metabolism, to regulate selectively outside the cells and inside them a stream of cations. In a small dose of levothyroxine produces an anabolic effect, and in the middle - mainly on tissues, cells. The medicine has a stimulating effect on the central nervous system, accelerates the processes of cleavage and metabolism of carbohydrates, fats, proteins.

Indications for use of the drug "L-thyroxine"

Feedback from experts about the drug is very positive. Assign a drug for replacement therapy in the case of hypothyroidism. In this case, the condition can have a different etiology. So, the medication is used for primary, secondary hypothyroidism, after operations on the thyroid gland or treatment with radioactive iodine, with myxedema, obesity accompanied by symptoms of hypothyroidism, cerebral pituitary pathologies, cretinism. In addition, the drug "L-thyroxine" (reviews of doctors say about the high effectiveness of the drug) is used in monotherapy with diffuse euthyroid goiter, euthyroid hyperplasia of the thyroid gland. Also with the help of the drug, malignant, highly differentiated hormone-dependent tumors of the thyroid gland are treated, including papillary and follicular carcinomas.

Form of issue and composition

A drug is given in tablets, enclosed in blisters. One unit of the agent can include the active ingredient - levothyroxine sodium - in the amount of 25, 50, 100 μg. Lactose is included in the number of auxiliary ingredients.

Method of using the drug "L-thyroxine"

The doctors' testimonies testify to the importance of compliance with the instructions regarding the method of taking the medicine. The whole daily dose should be taken at a time, preferably in the morning, half an hour before meals. In this case, the tablet should be swallowed, in sufficient amount washed down with water. For babies, the preparation is ground and then dissolved in a small amount of water until a slurry forms. The resulting mixture is given to the child half an hour before the morning of the first feeding (it is necessary to prepare the suspension immediately before the reception itself). The dose of the medication "L-thyroxine", which experts say is good in most cases, is forbidden to be selected independently. It should be installed by the doctor, depending on the age, the nature of the pathology, weight, functional state of the thyroid, determined by laboratory parameters. For adults, the recommended initial dose is 25-100 μg per day, for children 12,5-50 μg. Further, it is increased gradually (by 25-50 μg every 2-3 weeks), until a maintenance dose is reached.

"L-thyroxine": side effects

If you observe the indicated dosages, the negative effects after taking the drug usually do not arise. However, sometimes there are symptoms such as increased appetite, impaired kidney function, hair loss.

Contraindications

Do not take the medicine "L-thyroxine" (the doctors' warnings warn about this, as well as the instruction) in the presence of individual hypersensitivity to included in the components, with thyrotoxicosis, heart rhythm disorders, angina, pericarditis, myocarditis, at the age of 65 years.