The drug "Centel": reviews, user manual, description

Helminthiasis is called parasitic diseases of humans, plants and animals, which are caused by parasitic worms, such as helminths. Treat these diseases should be sure. Otherwise, the patient may develop fever, conjunctivitis, rashes on the skin of a polymorphous and exudative nature, as well as swelling of the face and upper respiratory tract.

There are many different drugs designed to treat helminthiosis. One of the most effective is Zentel. The use of this drug, its contraindications, cost and form of release will be presented further.

Composition, packaging, description and form of the medicinal product

In what form is the medicine "Zentel" made? Reviews report that this tool has two forms of release. Let's consider their composition in more detail.

• Homogeneous transparent solution of "Centel". The suspension for oral administration contains an active ingredient such as albendazole. Also this medicine includes the following additional components: potassium sorbate, sodium carboxymethyl starch, silicone antifoam 1510, sorbic acid, polysorbate 80, sorbitan monolaurate, benzoic acid, flavoring, glycerol, magnesium aluminum silicate, sodium saccharin and various flavoring additives. For sale, the agent in question is supplied in dark vials.
• "Centel" - tablets of oval form and pink color. They include such additional components as lactose, dye yellow sunset, povidone, croscarmellose sodium, magnesium stearate, corn starch, sodium saccharin, vanilla flavor, MCC, sodium lauryl sulfate, fruit and orange flavor. You can purchase this tool in contour cells.

Pharmacological characteristics

What is the drug Centel? Experts say that it has antiprotozoal and anthelmintic effects and belongs to the benzimidazole group of the carbamate.

This drug affects the intestinal and tissue forms of parasites. It also adversely affects adult helminths, eggs and larvae. Inhibiting the polymerization of tubulin, Zentel interferes with the metabolism of parasites and causes their death.

According to the instructions, the drug in question is active against:

• Trematodes;
• Nematodes;
• Cestodes;
• Protozoa.

It also affects tissue parasites, including alveolar and cystic echinococcosis. In addition, the drug is highly effective when:

• Capillarious disease, which developed due to Capillaria philippinensis;
• Neurocysticercosis, which was triggered by the invasion of Taenia solium larvae;
• Gnathostomosis caused by Gnathostoma spinigerum.

It should also be noted that this drug reduces or kills echinococcus cysts (granular). In this case, cysts caused by Echinococcus multilocularis immediately disappear.

Kinetics

Is the drug "Zentel" absorbed? Reviews say that after applying the drug inside its absorption is weak. Although fatty food improves its absorption.

The main metabolite of this drug is albendazole sulfate, which is very effective in the treatment of tissue infections.

The half-life of the metabolite is 8.5 hours. In this case, some of it is excreted in the urine, and the rest - with bile.

Indications

Medication "Centel", which will be reviewed below, is used for intestinal forms of helminthiases.

Short-term therapy of this drug is designed to treat the skin syndrome of Larva Migrans, and long-term therapy for systemic helminthic invasions.

Contraindications

The drug "Centel", the price of which will be listed below, is not recommended for hypersensitivity to its ingredients. Also, the medicine (in any form of release) is contraindicated to babies for up to a year. In addition, the medication in tablets is not prescribed for children under three years of age.

The agent should not be taken with retinal lesions, during breastfeeding, during pregnancy planning and in the process of bearing the fetus.

Instructions for use

Both forms of this drug are intended for oral administration. Use tablets and suspensions preferably at the same time (along with food).

Dosage and duration of treatment with this remedy depend on the indications and are determined by the treating doctor.

If the patient's condition does not improve, then you should consult a doctor. If necessary, the patient may be recommended a second course.

Adverse events

Reception of the drug "Centel" can provoke the following side reactions:

• Skin itching, nausea, increased level of liver enzymes;
• Leukopenia, rash, vomiting, hepatitis;
• Diarrhea, hives, Stevens-Johnson syndrome;
• Pain in the abdomen, aplastic anemia;
• Reversible alopecia, polymorphic erythema;
• Agranulocytosis, pancytopenia, fever.

Overdose and interaction with other medicines

In case of an overdose with this remedy, the patient experiences pronounced side effects.

When interacting with cimetidine, dexamethasone, and praziquantel, the concentration of metabolites in the plasma increases. As a result, the risk of overdose significantly increases.

Price and consumer reviews

How much is the preparation of Zentel? The price of this medicine in the form of tablets is about 190 rubles. As for the suspension, it is slightly more expensive (about 250 rubles).

Reviews about the facility in question can be found very different. In most cases, this drug copes with the task. After its administration, almost all the symptoms of helminthiasis disappear.

However, it should be noted that negative medicines can be found about this medication, which indicate the presence of a large number of side effects. Therefore, for the prevention of helminthiosis and treatment of children, this drug is used with extreme caution.

In addition, there are reviews that the drug "Zentel" does not always prove effective. In most cases, such messages are left by patients who were self-medicated. Therefore, experts recommend taking suspension or pills against parasites only for the doctor's prescription.