The drug "Buserelin". Instructions

The drug "Buserelin" refers to the pharmacological group of hormonal antitumor agents and hormone antagonists. The medication is available as a solution for injection. The drug is also produced in drops for intranasal administration. In pharmacies, it can be purchased and in a vial, the volume of which corresponds to one hundred doses of aerosol (nasal spray).

The drug "Buserelin", the instruction for which introduces the composition of this drug, as the main active ingredient contains buserelin acetate. An auxiliary substance intended for preservation is benzyl alcohol.

The drug "Buserelin" is an analogue of the natural hormone gonadotropin-releasing, synthesized by artificial means. The drug is prescribed for the course of treatment of tumors having a hormonal origin. The drug "Buserelin", the instruction to which explains in detail the mechanism of its action, can increase the number of hormones that are in the blood, due to influence directly on the pituitary gland. Approximately 12 to 14 days after the start of the drug, the production of luteinizing and follicle-stimulating hormones in the patient's ovaries ceases. This is due to the blockade of the gonadotropic process in the pituitary gland.

In turn, the synthesis of sex hormones in the ovary is suppressed and the amount of estradiol in the blood plasma decreases, which causes interruption of the menstrual cycle. In the treatment of oncology of the prostate, long-term use of the drug reduces the level of testosterone, causing "drug castration." The need to suppress the production of hormones occurs in the treatment of hormone-type cancer. For example, with prostate cancer or breast cancer. In such cases, sex hormones provoke an increase in the size of the tumor. After the drug is withdrawn, the amount of testosterone and estrogen contained in the blood is normalized. Monthly after "Buserelina" are restored independently after the termination of reception of means. When preparing for an operation with endometriosis, the purpose of the drug can reduce the size of the foci of pathology and their supply of blood, as well as reduce the inflammation of the affected areas. The use of the drug in the postoperative period reduces the adhesion process and the frequency of complications.

The drug "Buserelin", the instruction to which describes the main pathologies in which it is administered, is recommended for hormonal disorders. These include:

• Oncology of the breast;
• Endometriosis;
• Uterine myoma;
• Endometrial hyperplasia;
• Oncology of the prostate.

The drug is also used in the treatment of infertility.

The drug "Buserelin", the instruction to which warns about undesirable side effects that can occur when taking it, can cause headache and sleep disorders, depression and irritation of the retina (if the patient wears contact lenses). Also, nausea and vomiting, changes in appetite, impotence and dryness of the vagina, pain in the lower abdomen and ovarian cyst, bleeding menstrual like and allergic reactions are also likely. Sometimes, taking medication provokes irritation of the nasal mucosa with the occurrence of bleeding, hot flashes, increased sweating, dry skin, demineralization of bone tissue, gynecomastia, thrombosis, and swelling in the feet and ankles. This drug is forbidden to take during breast-feeding of a child, as well as pregnancy.