HealthPreparations

"Quetiapine": instructions for use, testimonials. Drug analogues

Mental disorders are diagnosed today quite often. The reasons for their development in the modern world are innumerable. However, there are a lot of drugs, the task of which is to fight against such pathologies. For example, one of them is Quetiapine. The instructions for using this remedy are very important for familiarization, as this is not a simple remedy for colds.

general characteristics

So, this drug is an antipsychotic and an atypical antipsychotic drug used in psychiatry. It is used to organize therapy for such pathologies as schizophrenia, depressive disorder, bipolar disorder, and others.

The drug works very simply. "Quetiapine" (instruction on the use of this drug is definitely included) has the property to change the activity of some substances found in the brain. It is produced in Russia. However, this does not mean that its cost is too low. It all depends on the dosage of the drug you are buying.

What components are included in the drug, which form of release exists?

So, if you were assigned "Quetiapine", the instructions for use describe its composition: quetiapine fumarate (the main active ingredient) is 25 -300 mg. Additional components are also present: giprolase, calcium hydrophosphate dihydrate, microcrystalline cellulose, magnesium stearate, starch, primogel. The film membrane of each tablet consists of talc, glycerin, hypromellose, silver dye.

Tablets are round, convex on both sides. They have a blue color with a pearly reflection. In addition, they have a different dosage. Packed in a blister pack of 30 or 60 pieces and are in a cardboard box.

Pharmacological action of the drug

Was Quetiapine appointed for you? The instruction tells about such pharmacodynamics: the main component is able to fight with a large number of receptors, especially with serotonin. In addition, it has an antagonistic effect on histamine and dopamine receptors, albeit to a lesser extent. That is, the action of the drug is based on blocking some receptors in the brain cells, inhibiting the metabolism in them.

Absorption of the drug is opal. At the same time, eating on the bioavailability of the drug has virtually no effect. Accumulates the substance in the liver, where it is neutralized. Excretion is performed mostly through the kidneys (78%) and together with feces (20%). The elimination half-life is approximately 7 hours. It must also be taken into account that the cleansing of the body from the drug largely depends on the age of the patient and the functionality of his liver.

What indications for use exist?

With some mental disorders, doctors appoint "Quetiapine". The instruction provides such indications for use:

1. Schizophrenia.

2. Acute or chronic psychosis.

3. Bipolar disorder, its manic phase of moderate or severe degree (although tablets can not prevent this condition).

4. Depressive state.

5. Serious behavioral disorders.

6. Dementia in the elderly.

7. Organic brain syndromes.

Whatever it was, before taking the advice of the doctor. Moreover, the product can only be purchased with a prescription.

Contraindications to use

With the appointment of the drug "Quetiapine", instructions for use, reviews and description of the product will help you understand its effects. It is important to familiarize yourself with the prohibitions and restrictions in which the drug is not recommended. There are such contraindications:

- Too high sensitivity to the drug.

- Age (up to 18 years).

- The period of bearing of the child and lactation.

- Simultaneous reception of some drugs: antifungal agents, "Erythromycin."

- Oncological diseases of mammary glands and brain.

- Cataract.

Dehydration.

- Severe systemic disorders in the body.

With caution, you need to prescribe a medicine if the patient has heart failure, arterial hypotension, cardiac hypotrophy, liver failure, convulsive seizures and epilepsy in the anamnesis. In addition, especially careful during admission, you need to be elderly and those who have a risk of developing thromboembolism.

Possible adverse reactions

Now it is necessary to deal with those negative reactions that can appear as a result of using the drug "Quetiapine". Instructions for use (tablets can not start and stop drinking on their own) provides the following possible side reactions:

- Pain and dizziness, a sense of anxiety, emotional emptiness, drowsiness or lack of sleep, increased excitability and hostility, tremors, convulsions. In addition, there may still be a weakening of the functions of the autonomic nervous system.

- Tachycardia, heart failure, orthostatic hypotension, chest pain.

- Nausea, dryness in the mouth, vomiting, diarrhea or constipation, pain in the abdomen.

- Allergic rhinitis, rashes on the skin, pharyngitis.

- Reducing the number of leukocytes in the blood, reducing the concentration of thyroxine.

- Lumbar pain, vision problems, weight gain, dry skin.

- Pain in the ears, weakening of the muscles.

- Infection of the urinary canal.

As you can see, this medicine can give a lot of adverse reactions, but if its effectiveness is higher than the probability of side effects, then the doctor has the right to prescribe a remedy.

Dosage and specific directions for admission

So, if you still had to buy Quetiapine, the instructions for use (the manufacturer of the drug is located on the territory of Russia) indicates the following dosage features:

- In acute or chronic psychosis, as well as schizophrenia, the tablets are taken according to the following scheme: the first day - 50 mg, the second - 100 mg, the third - 200 mg, the fourth - 300 mg. Further, the daily rate can range from 300 to 450 mg, depending on the severity of the pathology, the frequency of seizures.

- If the patient suffers from manic disorders in the background of bipolar disease, then this dosage is envisaged: the first day - 100 mg, the second - 200 mg, the third - 300 mg, the fourth - 400 mg. By the 6th day of therapy, a doctor can increase the dose to 800 mg per day. The daily increase in the amount of the substance should not exceed 200 mg.

The standard daily norm of the drug for patients varies between 400-800 mg. Particular care must be taken with elderly patients and people suffering from kidney or liver failure. Their initial dose is 25 mg per day. Daily increase in the rate is 25-50 mg. At the same time, one should constantly observe how the patient's organism reacts to treatment and increasing the dose.

There are certain features of the reception. For example, drink tablets better at the same time. Most often this is done in the evening before eating. The duration of therapy depends on its effectiveness, on the general condition of the patient and on the occurrence of undesirable consequences. Do not share or chew the tablet. You need to swallow it whole.

If you have not taken Quetiapine for more than a week, the instructions for use (the effect of the drug is effective only if you constantly use it) recommends that you consult a doctor. You may need to start again with a lower dose. Do not stop taking this medication yourself.

If an overdose occurs, which may indicate drowsiness, a decrease in pressure, an erratic heart rhythm, then you should immediately rinse the stomach to the patient. After that, to prevent intoxication of the body, you need to give him to drink several tablets of activated carbon.

If after an overdose the patient is unconscious, be sure to call an ambulance. Specialists, in turn, should perform intubation of the trachea, administration of laxatives and symptomatic treatment.

Note that during the application of the drug may develop orthostatic hypotension. In this case, the dose of tablets should be substantially limited. During the period of therapy, you should stop using alcohol.

Long-term treatment with high doses of the drug is possible only if the expected positive result was estimated before the start of the tablet taking, as well as the degree of potential risk.

Interaction with other medications

This issue is very important, since the treatment of psychosis and schizophrenia is complex. Particular attention should be paid to the interaction of Quetiapine with other drugs that affect the functioning of the central nervous system. They can have an additional sedative effect. Do not take the tablets with grapefruit juice.

Some remedies may reduce the effectiveness of Quetiapine, for example, Carbamazepine, Phenytoin. A substance such as thioridazine can increase the degree of cleansing of the body from this drug to 70%.

Features of storage facilities

If you are assigned "Quetiapine", the instructions for use (analogues you will consider further) provides for this product shelf life: 2 years. It must be stored in a place protected from light. It is desirable that the children could not get to the drug. The temperature at which the agent can retain its properties is 25 degrees.

Do not put packing with the product near heat sources. After the expiry date, the product is strictly prohibited.

What analogies can I use?

It should be noted that the cost of the medicine presented ranges from 250 to 2900 rubles per package. Everything depends on the dosage of the remedy. However, some patients try to look for a cheaper drug. If you are registered with Quetiapine, the instructions for use (synonyms for this tool may be of lesser value) suggest the following options:

"Nantarid."

"Victor."

- "Quentiaks".

- "Hedonin".

"Ketilept."

- "Kutipin".

- "Seroquel".

- "Quetitex".

"Ketiap."

- "Servitor".

"Lakvel."

These analogues are characterized by the presence of the same basic active substance. At the same time, their cost can be different. From this list you can choose exactly what you need. However, in occasion of analogues it is necessary to consult with the doctor.

Reviews about the medicine

If you need to purchase Quetiapine, the instructions for use (reviews help you understand the effect of the remedy) is the main document that must be read before using the substance.

Patients talk about this medication differently. They note the effectiveness of the drug. However, there are side effects too. For example, patients note weakness in muscles, clouding of consciousness, nausea.

As you can see, "Quetiapine" (the instruction, patients' reviews you already know) is a serious drug, which without a prescription in the pharmacy is not for sale. Also note that when using the tool, you need to be very careful. Be healthy!

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