Health, Preparations
Milgamma - instructions for use, description and contraindications
The drug Milgamma belongs to the group of combined medicines. The composition includes B vitamins and lipocaine. B vitamins are necessary for the full functioning of nerve tissue. They stimulate the regeneration of the nervous tissue, improve its blood circulation, anesthetize and positively influence the conductivity of impulses in the nervous system. This article describes the Milgamma drug, an instruction for the use of this drug, which is released in various forms.
Forms of release
The drug is produced in the form of a dragee, there are packages of 30 and 60 pieces. The form - dragee compositum is also available, types of packages are the same as with a simple dragee. In addition, this product is released as a solution for injections in ampoules of 2 cm3, the package includes 5 ampoules.
Composition of preparations
The solution for injection contains thiamine (vitamin B1), pyridoxine (vitamin B6), cyanocobalamin (vitamin B12). The tablets contain vitamins B1 and B6. Compositum contains: 100 mg of benfotiamine, 100 mg of pyridoxine hydrochloride and auxiliary substances. Excipients include: povidone; MCC; Triglycerides; Colloidal silicon dioxide; Carmellose sodium; shellac; talc; Sucrose; Acacia gum; Calcium carbonate; corn starch; Titanium dioxide; Macrogol 6000; Glycerol 85%; Polysorbate-80; Wax glycolic mountain.
Therapeutic effect of Milgamma
Thiamine improves synaptic transmission, thereby optimizing nerve conduction. With its lack, there is an accumulation of elements of the decomposition of carbohydrates in the nervous tissue. From the body, the components of thiamine decomposition go through the urinary system. Pyridoxine is involved in the formation of active mediators: dopamine, histamine, adrenaline, tyramine, serotonin. In addition, this vitamin takes part in the metabolism of amino acids. After the phosphorylation process, pyridoxine appears in the blood plasma, from which it enters the cell. Cyanocobalamin takes part in the synthesis of creatinine, choline, nucleic acids, methionine. Prevents anemia and is involved in the metabolism. In addition, it is an analgetic substance. After entering the bloodstream, it is absorbed by the liver cells, accumulated in the bone marrow, penetrating the hemoplacental barrier, enters the intestine with bile, where some of it is absorbed again.
Indications for use
The main indication for the appointment of the drug milgamma instruction indicates various disorders of the nervous system, such as: neuralgia, pain syndromes, neuropathies of different genesis, neuritis and polyneuritis, peripheral paresis. Taking medication during pregnancy and lactation: At pregnancy, the acceptable amount of vitamin B6 intake is 25 mg. In the Milgramma pellet, its content is 100 mg. Therefore, the drug during pregnancy and feeding is not prescribed.
Side effects
Perhaps the emergence of allergic reactions, which are manifested in the form of itching, rash, bronchospasm, Quincke's edema and anaphylactic shock. In addition, there is an acne, sweating, tachycardia.
Instructions for use
Milgamma - instructions for the use of the solution: in severe pain syndrome, it is better to start therapy with intramuscular injection of milgamma in a dose of 2 cm3 daily for 5-10 days, with a further transition, either to take a dragee, or to a less frequent administration. The drug is injected deep in the / m.
Milgamma - tablets, instruction: prescribe one dragee 3 times a day for 30 days. Tablets should be taken with a sufficient amount of water or other liquid. At the end of the month, 1 pills a day are taken to the reception.
Milgamma - compositum, instructions for use: the scheme of reception milgamma compositum is the same as that of milgamma tablets.
Contraindications for use
The use of the Milgamma drug is prohibited in severe forms of heart failure, in newborns (especially with prematurity), and in hypersensitivity to any component of the drug. Milgamma should be administered with caution in the presence of Cycloserine and Penicillamine.
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