Enzyme preparation "Pancreatin". Analogues

Pain and heaviness in the abdomen are periodically found in almost every person. Usually this happens after taking fatty foods, overeating, with disorders of the gastrointestinal tract. The digestive system contains many enzymes that break down proteins, fats and carbohydrates. Then the ground substances enter the small intestine. There they are absorbed and spread through the circulatory system of the body. Sometimes the process of splitting is broken, and the basic elements of food reach the intestine in unchanged form. This leads to a violation of absorption, as well as dyspepsia (diarrhea, stool retention). In some cases, the body's own enzymes do not have time to perform their function in the required volume, which is expressed in the severity of the abdomen, painful sensations in the epigastric region, right and left hypochondrium. Most often this is due to malnutrition. In such cases, the drug "Pancreatin" helps to remove unpleasant sensations, analogues of which are known to many.

Mechanism of action of the drug

In order to improve the digestive process, it is necessary to fill the lack of enzymes. The drug "Pancreatin" acts on this principle. It consists of a number of enzymes of the pancreas of pigs and cattle, which in their composition are suitable for the human digestive tract. The main active ingredients of the drug:

1. Lipase - for the splitting of fats.
2. Pancreatic amylase - grinds carbohydrates of food.
3. Proteases, among which there is chymotrypsin and trypsin - these enzymes affect the proteins of food.

If the doctor prescribed this drug, but it is not available at the moment, then it is possible to easily replace the drug "Pancreatin", analogues of which are available in any pharmacy. These include the following medicinal substances: Mezim, Pancreasim, Creon, Panzinorm, Festal, Gastenorm Fort, etc.

Indications for use

Enzyme preparations are used for impaired secretion of the pancreas. The causes can be different, most often it is a disease of the organs of the gastrointestinal tract. Indications are: pancreatitis of various etiologies, including alcohol, cystic fibrosis - a disease associated with violations of protein metabolism. In addition, when removing the gland, to compensate for the enzyme loss, use the drug "Pancreatin". Analogues of the medication are prescribed for the same disorders. In addition, these drugs are effective for dyspeptic disorders, flatulence, diarrhea, cholecystitis, bile duct disease, insufficiency of the small intestine and stomach when they are removed.

Differences between analogues of the drug "Pancreatin"

All the listed medicines have the same basis and the active substance - enzymes of the pancreas of animals. Therefore, when buying these funds, patients often ask questions: "Pancreatin" or "Mezim," which is better? Why is there a difference in price and does it affect efficiency?

In fact, the differences in analogues are small: they consist in the dosage of the main enzymes, the presence or absence of bile and hemicellulose in the formulation. For example, the medication "Mezim-forte" contains 3500 or 10,000 units of lipase, and has no additional components. In turn, the drug "Festal" contains more bile and hemicellulose. If you choose that it is better to buy the drug "Creon" or "Pancreatin", then pay attention to the degree of lack of enzymes, since the first has a large concentration of lipase, so it can be used in smaller quantities.

Contraindications to the use of the drug "Pancreatin" and its analogues

All enzyme preparations, regardless of the concentration of the active substance, can not be taken by newborns and children up to two years of age. This is due to the fact that they have not fully developed the functions of the digestive tract. Also, when hypersensitivity to pork and beef, intestinal obstruction and exacerbations of chronic diseases, the drug "Pancreatin" should not be used. Analogues also have these contraindications. It should be remembered that medications are used only for chronic inflammation of the pancreas. Acute pancreatitis is a contraindication to the use of enzyme preparations, as they can cause the eradication of the disease and worsen its prognosis.

Side effects of the drug and its analogues

Medications that have an enzyme pancreatin in their composition can cause local and general effects on the body. The general effects of the use of drugs include: hypersensitivity reactions, positive symptoms of peritoneal irritation, as well as a violation of absorption of folic acid. If you use drugs "Pancreatin" or "Mezim", then there may be local side effects, that is, violations in the digestive system. These include: nausea, vomiting, diarrhea or constipation, discomfort in the epigastric region. In the treatment of cystic fibrosis, intestinal obstruction can be observed.

Interaction with other medicines

With the simultaneous use of antacids (reduce the acidity of the stomach), the action of the drug "Pancreatin" and its analogues is weakened. If the patient uses iron or folic acid preparations, then enzyme medicines will help slow down or disrupt their absorption in the intestine.

Medicinal substances should be used after consultation with the attending physician. Medication "Pancreatin" can be used for minor digestive disorders (severity after fatty foods), analogues "Creon" and "Mezim" are prescribed for more severe processes (chronic diseases, pancreas removal).