"Affida Fort" (powder): instructions, testimonials, testimonials and analogues

Pain accompanies a person throughout his life. Despite all its negative manifestations, it is pain that serves as an indicator that something is wrong in the body, somewhere a failure has occurred, and it needs help. A group of painkillers is probably the most extensive drug market. Producers are ready to offer consumers pain medication as a strictly directed action, as well as medicines of combined effect, which simultaneously have analgesic, antipyretic and anti-inflammatory effects. One such is the drug "Affida Fort", proposed to consumers by the Swiss company "Schonen" at the end of 2013.

Main purpose

The main active substance of the new drug is nimesulide in a volume of 100 mg in one sachet (sachet). This substance is classified as a group of non-steroidal anti-inflammatory drugs. Of the excipients in the drug are cetomacrogol, maltodextrin, sucrose, citric acid and flavor ("Orange").

The main purpose of "Affidita Fort" - it can be said, novelties in the pharmaceutical market is the removal of acute pain (joint pains of different genesis, primary dysmenorrhea, menstrual and toothache), symptomatic treatment of joint diseases with severe pain syndrome. In simple words, the main active substance of the drug (nimesulide) inhibits or suppresses the inflammatory process, thus having a pronounced anti-inflammatory effect.

Dosing regimen

The optimal option is the appointment of Affida Fort by a medical professional after a thorough assessment of the patient's health condition, taking into account all possible risks. In general, the medication is indicated to be taken in a minimally effective dosage to relieve the pain syndrome and for the shortest period of time. The period of therapy can last no more than 15 days. The maximum possible daily dose of the drug "Affida Fort" instructions for use regulates as 200 mg of the main component: 1 packet of nimesulide in a volume of 100 mg twice a day. However, this applies only to adult patients. Children under 12 years of age are not allowed to take the medication. For adolescents over 12 years of age, patients with mild to moderate renal impairment do not undergo a dose adjustment.

Take the medication inside after eating, before stirring the contents of the sachet in the water.

Nimesulide is the main active ingredient

"Nimesulide" manufacturers offer buyers in several forms of release. These are tablets, suspension, powders and gel. The area of application of this drug is much wider than that of "Affida Fort". The opinions of medical workers and patients are in solidarity with the fact that Nimesulide is very, very effective in a number of serious diseases accompanied by a fairly severe pain syndrome. The drug is prescribed for osteoarthritis, extra-articular rheumatic diseases.

A fairly good result can be achieved by using Nimesulide to relieve pain and inflammation after surgical intervention. It is able to minimize or completely suppress pain and fever during acute inflammatory processes in the upper respiratory organs. There is clinical evidence that the analgesic, analgesic effect with the "Nimesulide" is developing rapidly, literally in the first 20 minutes. For this reason, the drug can be taken with paroxysmal pain.

Tablets and powders are for adults. Suspension or syrup "Nimesulid" (as opposed to "Affida Fort" (powder)) instruction regulates for admission to children under 12 years old. Dosage of this form of the drug based on 1.5-3.0 mg per 1 kg of body weight per day. Usually the whole daily dose is divided into 2-3 doses. The maximum allowable dose for a child is 5 mg per 1 kg of body weight. The period of therapeutic therapy is no more than 2 weeks. Otherwise, side effects may occur.

Gel "Nimesulid" is effective for eliminating pain in soft tissues and joints, when injuring muscles and ligaments, with stretching. Apply the product on a dry clean skin with a thin layer, do not rub it, and apply bandages is also not recommended. You can use the gel up to 4 times a day. Sometimes, during application, there may be local reactions on the skin: itching, redness, peeling.

Contraindications to taking the drug

Like any drug, "Affida Fort" is contraindicated in those patients who are hypersensitive to its main active ingredient (nimesulide) or to auxiliary components. You should not take the medicine and those who have a history of increased sensitivity to the use of acetylsalicylic acid, manifested in bronchospasm, urticaria, rhinitis.

The same applies to the use in the treatment of other non-steroidal anti-inflammatory drugs. In addition, the "Affida Fort" (powder) instruction prohibits people who suffer frequent relapses of peptic ulcer of the stomach or duodenum, various other diseases accompanied by bleeding. Contraindicated "Affida Fort" patients with serious deviations from the norm of the process of blood coagulability, severe forms of failure in the functioning of the heart, kidneys, liver. In addition, "Affida Fort" is a drug that is inadmissible in use for dependence on alcohol and drugs, at elevated temperature and the presence of symptoms of an infection similar to influenza.

Possible side effects

Clinical studies have revealed the presence of certain side effects when using "Affidus Fort". They can manifest themselves from different body systems. The circulatory and lymphatic systems may respond to anemia, in rare cases, thrombocytopenia or pancytopenia may develop. Reactions of hypersensitivity may respond to the immune system, although in rare cases an anaphylactic shock may occur .

From the side of the nervous system, dizziness, drowsiness, headache, Reye's syndrome can sometimes appear. Like any other, including anti-inflammatory drugs, the gastrointestinal tract can respond. Here manifestations can be very different. More often there is a nausea, vomiting, a diarrhea, is more rare - a gastritis, a meteorism, locks. In exceptional cases, gastrointestinal bleeding, ulcers and perforation of the stomach and duodenum may occur.

The urinary system in some cases may respond to the drug by delayed urination, hematuria and dysuria. In rare cases, kidney failure, interstitial nephritis can develop.

From the side of the vascular system, sometimes (not often), the appearance of hypertension is possible. In rare cases, blood pressure may fluctuate and blood flow to the face may be felt under the influence of "Affidus Fort". The use of the drug may also affect the respiratory system. Sometimes there may be shortness of breath, in rare cases - bronchospasm, asthma. Sometimes patients complained of having a tachycardia.

Skin and subcutaneous tissues can have their own principles of responding to the medication. Sometimes there is increased sweating, rashes on the skin, itching. Occasionally, dermatitis or erythema may occur. In rare cases, the manifestation of urticaria, angioedema, edema of the face, toxic epidermal necrolysis.

Exceeding the maximum allowable dose: consequences

In most cases, exceeding the permissible dose is manifested by nausea, vomiting, pain in the epigastric region, drowsiness. Usually these manifestations are not catastrophic and completely reversible, even if some kind of supportive therapy is required. In rare cases, when using a large dose of "Affida Fort" (powder), the instruction warns about the possibility of occurrence of gastric bleeding. Also, there may be an increase in blood pressure, the development of acute liver failure, the state of oppression of respiratory function, coma. Anaphylactoid reactions can occur both with the administration of therapeutic doses of "Affidus Fort" and with an overdose.

In case of reception of an inadmissible large dose of the drug, patients should be assigned maintenance and symptomatic treatment. There is no specific antidote at present. There is also no information on the effectiveness of removing nimesulide from the body using the hemodialysis procedure. However, considering the fact that the degree of binding of the main active component of "Affidida Fort" with proteins is more than 97%, it can be concluded that hemodialysis will not give a noticeable positive effect. For the same reason, such measures as increased diuresis, alkalinization of urine, and hemoperfusion will be ineffective.

In the period up to 4 hours after taking a large dose of medicine experts recommend vomiting. It is justified in the case of an overdose of Affidah Fort, the use of activated charcoal (from 60 to 100 mg for adult patients). In the process of supporting and symptomatic therapy, you must closely monitor the functioning of the liver and kidneys.

Features of the application of "Affida Fort"

As mentioned earlier, in order to minimize the likelihood of side effects of the drug, it is necessary to take a minimally effective dose and in the shortest possible period. During the treatment course, you need to monitor your health. If a positive effect is not observed, and the patient's condition does not improve, the drug should be withdrawn.

The liver of the patient who receives the "Affida Fort" is subject to close monitoring by medical workers. This body can give a sufficiently serious reaction to the drug until the death (rarely). Therefore, "Affida Fort", as, indeed, other non-steroidal pain medications, with abdominal pain, nausea, vomiting, anorexia, staining of urine in a dark color must be canceled.

Similarly, specialists come when changing the indicators of functional liver tests. If the drug was taken for a short period of time, as a rule, lesions in the liver are reversible. In the future, "Affida Fort" for such patients is prohibited.

As a consequence of the above, experts recommend avoiding the simultaneous reception of "Affidus Fort" with any drugs that are hepatotoxic (damaging the liver, disrupting its operation). Also, such actions are not acceptable from the "Affida Fort", how to take it in parallel with alcohol (again because of the risk of developing adverse reactions from the liver).

Also, experts do not recommend combining the reception of "Affida Fort" with other nonsteroidal anesthetics. When bleeding occurs in the gastrointestinal tract, the drug is also canceled. Elderly patients in whom taking medication can cause abnormalities in the functioning of the heart, liver, kidneys, it is recommended to conduct constant clinical monitoring of the condition.

Another feature is the fact that Affida Fort influences the functioning of platelets. However, it is not necessary to prescribe it instead of acetylsalicylic acid for prophylaxis in the field of cardiology.

The drug has a depressing effect on fertility in women. For this reason, it is not prescribed to women planning to become pregnant. Patients who are being examined for infertility should also be designated "Affidita Fort".

"Affida Fort" and reproduction

"Affida Fort" instructions for use prohibit future mothers during the third trimester of pregnancy. The main active ingredient, nimesulide, is capable of provoking pulmonary hypertension, premature closure of the ductus arteriosus, and water scarcity. Against the background of the application of "Affida Fort" in pregnant women, the risk of bleeding, peripheral edema increases. Labor can be weakened. In addition, there are statistics on kidney failure in newborn babies, whose mothers took "Affida Fort" at the end of pregnancy. Specialists prefer not to prescribe medication during the entire pregnancy, because there is a potential risk for the body of a woman and a child.

Price range

The price range of the drug is quite extensive. 1 sachet, 6 and 30 sachets in the package - that's, in fact, the form of the drug "Affida Fort". The price, of course, depends on the volume of the package. In general, this drug is in great demand in Ukraine. However, pharmacy chains in Russia can offer their customers this drug as an effective non-steroidal anesthetic.

One packet of "Affida Fort" can be purchased for a sum of 10 to 15 rubles. Packing of 6 bags will cost the Russian consumer in the amount of 100 rubles to 200 depending on the region. The price for a package of 30 packages is in the range from 240 rubles to 500.

Consequently, "Affida Fort" - an analog of "Nimesil" - in price terms is more accessible to a wide range of consumers with different financial capabilities, which can not be said about the "Nimesil" itself. The cost of this drug, for example, for a package of 30 packets ranges from 640 rubles to 890.

The opinion of patients who took "Affida Fort"

The bulk of reviews about the drug has a positive color. Many patients regulate the drug as an effective analgesic medication for pain of very different origin. The effect can be felt already after 10-15 minutes after taking the drug, which is very important with a severe pain syndrome. A separate group positively assesses both Affida Fort and similar non-steroidal painkillers as effective anti-inflammatory in osteochondrosis, intervertebral hernia, various joint pain. A separate group of patients (women) assess the drug as highly effective in painful menstrual cycles.

But you can not say that the reviews are only positive. The drug has a number of side effects. And from time to time those or other of them manifest themselves in individual patients. Most often they complain of dizziness, drowsiness, manifestations of the gastrointestinal tract. As for the reaction in the gastrointestinal tract in the form of bleeding, they generally can occur suddenly, despite the fact that before such cases the patient was not, and in the anamnesis it is not fixed.

In any case, pure water can be absolutely safe. For any non-steroidal pain medication, even if the same "Affida Fort" (powder) - the instruction states a number of contraindications and side effects. And to understand all this variety of scientific words, terms and figures only a doctor can. Therefore, if all medications, whatever diseases they treat, simple or complex, will be prescribed by the attending physician, and the dosing regimen will be chosen, then the effect from them will be maximum with minimal risks of side effects.