Zinaprim: instructions for use, analogues and reviews

Zinaprim is a popular antibacterial drug used in veterinary practice for the treatment of a wide range of infectious diseases of domestic and farm animals. It is available in the form of an injection solution or a fine powder for dilution with water and oral administration.

The composition of the drug "Zinaprim"

Instructions for use indicate the content of the two main operating components, such as:

• Sulfamethasine;
• Trimethoprim.

Both substances are of synthetic origin. Their combination in the right concentration enhances the effect of each other (synergism) and gives a powerful bactericidal effect. The mechanism of action is aimed at blocking all important physicochemical processes occurring in the cell. Due to this spectrum of activity of the drug covers a large number of pathogenic bacteria-pathogens of dangerous diseases:

• Escherichia coli;
• Clostridium spp .;
• Salmonella spp .;
• Proteus mirabilis;
• Haemophilus influenza and gallinarum;
• Streptococcus pneumoniae, pyogenes, faecalis, and others;
• Staphylococcus aureus;
• Brucella spp.

Excipients may be citric acid, metabisulphite or sodium hydroxide, hydrochloric acid, deionized water.

As analogs can be called "Sulfatrim", "Sulfprim 48", "Trimetosul", "Dietrim". What kind of drug to choose in this or that case, the doctor should decide.

Indications for use

The drug is effective against a wide range of bacterial infections of domestic and farm animals. Among them:

• Infections of the lungs, bacterial infection of the blood (septicemia), enteritis in cats and dogs;
• Pneumonia, gastroenteritis, mastitis, vibriosis, brucellosis, salmonellosis, urogenital infections, purulent inflammation, skin diseases in large and small cattle ;
• Diarrhea, parotid inflammation (parotitis) and pneumonia in horses;
• Suppuration, malignant edema, dysentery, pig pneumonia;
• Pasteurellosis, pneumonia, rhinitis, colibacillosis, enteritis of rabbits;
• Infectious complications of viral diseases, pasteurellosis, salmonellosis, colibacillosis, streptococcal infections of poultry.

Judging by the reviews, this is a very effective drug. Rabbits say that this remedy helps with such a disease as coccidiosis. However, before starting treatment, you should always consult a veterinarian.

Zinaprim: instructions for use in veterinary medicine

The method of application is different for individual groups of animals. If necessary, pre-consult a veterinarian. The daily dose of the drug for cattle, goats, rams and pigs is 1 g of powder or 1 ml of solution per 10 kg of body weight. The same relationships apply to domestic animals. At first, the interval between doses should be at least 12 hours. The duration of such treatment is from 3 to 5 days. If necessary, increase the dose of Zinaprim.

Instructions for use for rabbits involves the use of 1 g of funds per 1 liter of water for drinking on the first day of treatment. In the next 2 or 3 days, the dose is reduced by half and limited to only a liter of water per day, with Zinaprim dissolved in it.

Instructions for use for birds are similar. However, it is forbidden to use it for the treatment of laying hens, since the product is attached to eggs, which makes this food unsafe. To treat the disorder of the gastrointestinal tract of chickens, you can use both powder and solution of the drug Zinaprim. Instructions for use for chickens are similar to those for adult birds.

The solutions are prepared daily in an amount that satisfies the natural needs of the animal. For the period of treatment, the diluted drug should be the only source of drinking water. Those who met all the requirements listed in the reviews most often characterize the drug effective and effective.

Being in the body

The drug is rapidly absorbed through the gastrointestinal tract or injection site and distributed throughout the body as soon as possible, penetrating all tissues and organs. Most of the sulfamethasin and trimethoprim are administered with urine in the form of compounds after a while, the smaller part with bile.

The components of the drug can settle in the tissues for a long time. For this reason, meat and milk of animals treated with Zinaprim should not be eaten. Instruction for use warns that slaughter of animals for meat should be made only after 5 days after the use of the product. Do not use the eggs of birds that have been treated. "Zinaprim" is a veterinary drug and, according to the degree of influence on the human body, was ranked in the 3rd class of danger.

Side effects and contraindications

Accurate and conscientious compliance with all recommended doses of application does not bear a negative result. However, prolonged use can lead to diarrhea, vomiting, nausea, impaired renal function, digestive disorders caused by the drug Zinaprim.

The instructions for use warn of the danger of intoxication during an overdose. In this case, the pathological damage of the kidney tissue and disruption of their work occurs. If this happens, the medication should be urgently discontinued and appropriate antidotes introduced to the affected animal. In case of unpleasant symptoms, with full observance of all established doses, individual intolerance of any components is possible.

Animals suffering from renal and hepatic insufficiency should be given the drug with great care, as this can cause serious disruptions in the operation of these systems. During pregnancy and feeding of cubs with milk it is impossible to use "Zinaprim".

Precautions when working with the drug

Instructions for use indicate the need to comply with basic hygiene measures. Before and after using Zinaprim, you should thoroughly wash your hands and open body parts to prevent the penetration of the drug into the human body or get on the mucous membranes of the eyes and nose. Also, care should be taken to ensure that this product is stored at home under temperature conditions and in a place inaccessible to children.

When using the powder, it must be prevented from getting on the skin, using protective gloves. It is advisable not to smoke, drink or eat during the procedure. It is highly not recommended to work with this product for pregnant and lactating women. And also apply the drug near food, tableware, household appliances. The ingestion of Zinaprima can cause severe poisoning. If this still happens, you need to see a doctor.