"Venlafaxine": reviews, instructions for use, analogues

Nowadays, most people are exposed to stress and depression, which not only interfere with normal living, but also have a detrimental effect on health. A strong personality can cope with troubles and difficulties on his own. Some do not succeed, and they fall into a depressed state, which requires the intervention of a professional specialist and treatment. One of the most common and popular antidepressants is the preparation "Venlafaxine". Instruction, feedback - all this information should be studied before starting therapy.

Effect of the drug

The remedy refers to a group of drugs that are prescribed to eliminate a depressive condition. The medication has a unique chemical composition that is not similar to other groups of antidepressants. The preparation has two active enantiomeric racemic forms.

Getting inside, the main substance enhances neurotransmitter activity in the central nervous system. Together with the metabolite of the drug, they are considered to be potent inhibitors of serotonin and norepinephrine and reduce the reuptake of dopamine by neurons, reducing beta-adrenergic reactions.

The drug, getting inside, quickly absorbed from the stomach. After a single application in a dose of up to 150 mg, the maximum effect of the drug in plasma is achieved after three hours. At the first passage through the liver, the Venlafaxine agent is strongly metabolized. The doctors' comments show that the medicine can show a good result already at the beginning of therapy.

Indications and contraindications

The drug is used for depressive states. There are contraindications. This includes:

• Kidney failure;
• Liver pathology;
• Age to 18 years;
• Hypersensitivity to the active ingredients;
• pregnancy;
• lactation.

Dosage

The product is intended for oral use. At the beginning of treatment it is recommended to drink 75 mg of the drug in two divided doses (morning and evening). If the positive dynamics of the disease is not observed, the dosage in a few weeks can be increased to 150 mg per day, also breaking it down twice. In severe forms of depression, when the patient is shown to be hospitalized, the dose of the drug can immediately be 150 mg in two divided doses. Then you need to reduce the dose to 75 mg per day and continue treatment until the desired result.

The maximum allowable dosage should not exceed 375 mg per day. The course of treatment depends on the individual characteristics of the body and the severity of the disease. Elderly, the dosage should be given in the lowest doses. All patients during the treatment process are under the supervision of a doctor. It is impossible to abolish the drug drastically, it is necessary to gradually reduce the dose to zero so as not to cause the "Venlafaxine" drug withdrawal syndrome . The instructions for use contain detailed information on the dosage.

Interaction with other drug groups

The drug should not be taken with the following medicines:

• MAO inhibitors;
• "Lithium";
• "Haloperidol";
• "Clozapine";
• "Cimetidine";
• Warfarin.

With simultaneous admission with an antidepressant, women should use reliable methods of protection from unwanted pregnancy. During the carrying of the fetus and during breastfeeding it is strictly forbidden to drink "Venlafaxine" tablets. The reviews show that the drug has a negative impact on the intrauterine development of the baby. The active ingredient is also given to the baby along with breast milk.

Side effects

In general, the occurrence of side effects depends on the prescribed dose of the drug and on the increased sensitivity to the drug. The most common symptoms of side effects are:

• nausea;
• Vomiting;
• Decreased appetite;
• Dry mouth;
• constipation;
• An increase in the cholesterol in the blood;
• weight loss;
• Redness of the skin;
• Increase in pressure indicators;
• tachycardia;
• Nightmarish dreams;
• sleep disturbance;
• Tremor of hands;
• headache;
• dizziness;
• In rare cases, anaphylactic reactions.

Before starting treatment, it is necessary to study all contraindications to the use of "Venlafaxine". The patients' comments indicate that the medicine in a short time helps to cope with the symptoms of depression and return to a normal way of life. But also side effects with wrong therapy develop quite often.

With caution, you need to prescribe medication under the following conditions:

• A recent heart attack;
• Severe heart failure;
• Hypertension;
• Manic states;
• tachycardia;
• glaucoma;
• Decreased body weight;
• Tendency to bleeding;
• epilepsy;
• It is not recommended during the treatment to drive vehicles and perform work related to the danger.

The drug is dispensed in a pharmacy under a prescription. The dosage of the drug can be adjusted and prescribed only by a doctor. Keep the medicine "Venlafaxine" in a dry and inaccessible place for children. Analogues of the drug can be purchased at an affordable price in any pharmacy. The most popular substitutes will be described below.

Duplex

Refers to the group of antidepressants. The chemical composition of the drug can not be attributed to any type of known remedy for depression. It has two active enantiomeric racemic forms. The drug is already within two hours after ingestion reaches the maximum concentration in the plasma. The main substance and its metabolites are potent inhibitors of the reuptake of serotonin and norepinephrine and quite weakly inhibit the reuptake of dopamine by neurons. The agent does not inhibit the activity of MAO inhibitors. Basically, the remedy is excreted by the kidneys. An identical effect on the central nervous system is provided by the preparation "Venlafaxine". Experts' reviews show that the drugs are very similar and can replace each other.

Indications and contraindications

The drug is prescribed to treat depression of a different nature. There are a number of contraindications when a medicine can not be taken:

• Severe kidney and liver pathology;
• Fruit bearing;
• lactation;
• Reception in the complex of MAO inhibitors;
• Hypersensitivity to the substance;
• Age to 18 years.

Tablets are intended for oral use. The recommended dose is 75 mg per day, in two divided doses. It is advisable to drink the medicine at the same time in the morning and in the evening. If the proper therapeutic effect is not observed within two weeks, the dosage of the agent can be increased to 150 mg per day, dividing it by two times. As the symptoms of depression improve, the drug decreases in a dose and maintenance therapy remains until full recovery. The maximum allowable dose should not exceed 375 mg per day.

The drug is recommended to be canceled gradually, so that the patient does not develop a sudden cancellation syndrome. Dapfix can cause weight loss. About this patients leave and about the preparation "Venlafaxine" reviews. Lose weight with these pills can be fast enough. However, it is not recommended to use a medicine for this purpose.

Interaction with other means

The admission with the following groups is prohibited:

• MAO inhibitors;
• "Lithium";
• "Clozapine";
• "Cimetidine";
• "Warfarin".

Patients who suffer from chronic diseases and are forced to constantly undergo medical therapy, it is worth consulting with a doctor about the possibility of combining drugs.

The drug is not recommended to drink during pregnancy. Therefore, during the period of therapy, reliable methods of contraception should be used. Also, when breastfeeding, it is not possible to use Dapfix medication, like its analogue, Venlafaxine. Instructions for using the tool will tell you in detail about the indications and contraindications to use.

Side effects

Basically, the medicine does not cause side effects and is well tolerated by patients. In exceptional cases, the following symptoms may develop:

• nausea;
• Vomiting;
• dizziness;
• constipation;
• Pain in the epigastric region;
• Decreased appetite;
• weight loss;
• Nightmarish dreams;
• Retention of urine;
• sleep disturbance;
• Manic reactions;
• Increased pressure, tachycardia.

If these symptoms occur, you should immediately consult a doctor. The "Venlafaxine" agent has identical recommendations. Analogues means, such as "Dapfix", can fully replace the original and remove in a short time the causes of depression.

The medicine is released in the pharmacy only on prescription. Keep the product in a dry and dark place where children can not reach it. Do not administer medication to patients with severe renal and hepatic insufficiency. Also in the elderly, the dosage should be minimal.

«Efektin»

Refers to a group of antidepressants of a new generation. By its chemical composition, this drug can not be compared with other drugs that are used to treat depression. The main substance of the tablets, venlafaxine, and its direct metabolite are considered to be increased inhibitors of the reuptake of serotonin and norepinephrine and to a lesser extent dopamine. The drug can cause increased transmission of impulses to the central nervous system.

After getting into the stomach, the substance is quickly absorbed. The maximum effect in plasma occurs in 2 hours. Basically, as metabolites, the drug "Efetin" is excreted with the kidneys, as is the medical device "Venlafaxine". Reviews about these two remedies can be heard mostly positive.

Indications and contraindications

A drug is prescribed to treat and prevent depression of various etiologies. Do not take the drug in the following cases:

• Recently suffered myocardial infarction;
• Hypersensitivity to components;
• pregnancy;
• lactation;
• Children under 18;
• high blood pressure;
• tachycardia;
• Convulsions;
• Tendency to bleed.

Dosage and overdose

At the beginning of the treatment process, the dose should not exceed 75 mg tablets per day. The drug is taken orally and divided into two doses, in the morning and in the evening. After a week if there is no improvement, the dosage is increased to 150 mg per day. It is necessary to drink 75 mg twice a day. The daily dose of the drug should not exceed 375 mg. In the future, if you receive a positive result and reduce the causes of depression, the drug should be reduced to the minimum consumption.

Continue the course of treatment is necessary until complete recovery. Cancel the remedy gradually. In the same dosage, the preparation "Venlafaxine Retard" is prescribed. The reviews show that the substitutes have the same recommendations.

In case of an overdose, the following symptoms occur:

• dizziness;
• nausea;
• Lowering of blood pressure;
• tachycardia;
• Convulsions.

With untimely care, the patient may die. If symptoms of an overdose need to wash the stomach, give a drink absorbent and connect detoxification therapy.

Women after 50 years of age are often prescribed drugs "Efektin", "Venlafaxine." Climax feedback provides an opportunity to understand that medication therapy helps to cope with depression that has emerged against the backdrop of hormonal changes. It should be borne in mind that elderly patients should be prescribed medication in a reduced dosage. Self-medication is undesirable.

Medication "Efetin" is not compatible with the following drugs:

• MAO inhibitors;
• "Cimetidine";
• Risperidone;
• "Caffeine";
• "Diazepam."

The drug can cause withdrawal syndrome in a newborn, so it is not recommended to take it during pregnancy and feeding.

Improper use of the drug may lead to the development of the following side effects:

• dizziness;
• nausea;
• Vomiting;
• constipation;
• stomach ache;
• sleep disturbance;
• Nightmarish dreams;
• weight loss;
• A decrease in blood pressure;
• tachycardia;
• Urine retention.

Reviews about the product "Venlafaxine" and its analogues

Basically, the drugs are well tolerated. With the development of side effects, the medicine should be canceled and symptomatic treatment should be prescribed. Before the beginning of therapy it is necessary to study all the side effects that drugs can cause.

Many experts recommend that when using depression, "Venlafaxine" tablets should be used. The reviews show that the medicine helps to restore the patient to normal life in the shortest possible time.

The described medicines are not addictive. The drugs are available in the form of tablets, which are convenient to take orally. In a short period of time, you can get rid of various forms of depression and return to normal life. It is worth consulting with a doctor before using the medication "Venlafaxine". The reviews show that side effects develop more often if the patient is self-treated.