"Tsinarin": instructions for use, reviews, analogues

Calcium channel blockers are called a heterogeneous group of drugs that have the same principle of action, but differ in some properties, including kinetic parameters, tissue selectivity and the effect on heart rate.

The main principle of action of such drugs is that they are able to inhibit the penetration of Ca ions from the intercellular space into blood vessels and heart muscle cells through calcium channels (slow ones). This leads to a pronounced vasodilating action.

The most popular calcium antagonist is the drug "Tsinarin." Instructions for use, cost, reviews and composition of this tool will be described below.

Form of release, packaging, description, composition

The drug "Tsinarin", reviews about which are positive, goes on sale in the form of biconcave, round and white tablets. Their main component is cinnarizine. In addition, the drug includes excipients in the form of povidone K25, lactose, wheat starch, silicon dioxide colloid and magnesium stearate.

You can purchase this tool in contour cells.

Characteristics of the preparation

Instruction for the use of the drug "Tsinarin" reports that it is a selective antagonist of calcium channels (slow). It reduces the flow of Ca ions into the cells and reduces their number in the depot of the plasmolemma, and also enhances the vasodilating effect of carbon dioxide and reduces the tone of the musculature of the arterioles.

By directly affecting the vessels, this drug significantly reduces their response to nutrients (norepinephrine, adrenaline, angiotensin, dopamine and vasopressin). It should also be noted that the medicament in question has vasodilating properties, including in relation to the vessels of the brain. In this case, it does not affect BP.

The drug "Tsinarin", the price of which is indicated below, shows moderate antihistamine activity, reduces the excitability of the vestibular apparatus and reduces the tone of the sympathetic NC. This drug effectively manifests itself in the initial failure of cerebral circulation, and in chronic. In people with impaired peripheral circulation, it improves the blood supply of all tissues and organs. It also reduces the viscosity of blood, increases the elasticity of erythrocyte membranes and muscle resistance to hypoxia.

Kinetics of the drug

What are the kinetic features of the drug "Tsinarin"? Instructions for use say that this remedy resorbed in the intestines and stomach. The peak of its concentration in plasma is reached after three hours. The connection of cinnarizine with plasma proteins is 91%. The drug is completely metabolized in the liver. Its half-life is four hours. There is a drug with urine and calves.

Indications

The drug "Tsinarin" is shown to be taken at:

• Senile dementia;
• Ischemic stroke;
• Craniocerebral trauma;
• Post-stroke states (including hemorrhagic stroke);
• Discirculatory encephalopathy;
• For the prevention of kinetosis (sea or air sickness, as well as during motion sickness);
• Vestibular disorders (including Meniere's disease, noise in the ears, dizziness, nystagmus, vomiting and nausea of labyrinthine origin);
• Migraine (for the prevention of seizures);
• Violation of peripheral circulation.

Contraindications to taking tablets

At what conditions can not prescribe the drug "Tsinarin"? Instruction for use informs that this remedy is contraindicated when:

• Hypersensitivity;
• Bearing of the fetus;
• Breastfeeding.

It should also be noted that this drug is administered with caution in Parkinson's disease.

Preparation "Tsinarin": instructions for use

Take these pills should be inside, preferably after a meal.

When the blood circulation of the brain is disturbed, the drug is prescribed in the amount of 25-50 mg three times a day, and in the case of impaired peripheral circulation - 50-75 mg with the same multiplicity.

With vestibular disorders, the drug is recommended to take 25 mg three times a day. With kinetosis or the so-called "road" disease, adult patients are prescribed 25 mg of the drug 30 minutes before the road. If required, the medicine is taken again after 6 hours (in the same amount).

For children, this drug is prescribed in an amount of 1/2 dose from an adult.

With high sensitivity to medicines, therapy starts with half the dosage, gradually increasing it. The course of treatment can last from 2-3 weeks to several months.

Adverse events

This drug can cause the following side reactions:

• Dry mouth, indigestion, epigastric pain, cholestatic jaundice;
• Drowsiness, headaches, fatigue and extrapyramidal disorders (eg, increased muscle tone, limb tremor, hypokinesia);
• Red flat lichen, sweating, lupus-like syndrome, skin rash;
• Allergic phenomena, weight gain, lowering blood pressure.

Price, product release, analogues and reviews about it

The release of drugs belonging to the group of calcium channel blockers is carried out according to the doctor's prescription. The price of this medicine is about 20-50 rubles.

If necessary, this drug can be replaced with drugs: Vertizin, Diziron, Stugesin, Stugeron, Cinazine, Cynedil, Cinnarizine, etc.

Most consumers who take this antagonist say that it is a very effective and effective drug. The reception of "Tsinarin" tablets contributes to the elimination of vestibular disorders and disorders in the process of circulation. In addition, this medicine positively affects the human body in migraines, senile dementia and post-stroke states.

It should also be noted that this remedy often causes side reactions. To avoid their development, all the doctor's recommendations should be strictly observed. Taking tablets "Tsinarin" in its personal discretion is prohibited. They should be prescribed only by the attending physician.